A draft genome of Yersinia pestis from victims of the Black Death KI Bos, VJ Schuenemann, GB Golding, HA Burbano, N Waglechner, ... Nature 478 (7370), 506-510, 2011 | 909 | 2011 |
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy L Ejim, MA Farha, SB Falconer, J Wildenhain, BK Coombes, M Tyers, ... Nature Chemical Biology 7 (6), 348-350, 2011 | 585 | 2011 |
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance AM King, SA Reid-Yu, W Wang, DT King, G De Pascale, NC Strynadka, ... Nature 510 (7506), 503-506, 2014 | 578 | 2014 |
Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance JM Stokes, CR MacNair, B Ilyas, S French, JP Côté, C Bouwman, ... Nature microbiology 2 (5), 1-8, 2017 | 328 | 2017 |
Targeted enrichment of ancient pathogens yielding the pPCP1 plasmid of Yersinia pestis from victims of the Black Death VJ Schuenemann, K Bos, S DeWitte, S Schmedes, J Jamieson, A Mittnik, ... Proceedings of the National Academy of Sciences 108 (38), E746-E752, 2011 | 318 | 2011 |
Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics CR MacNair, JM Stokes, LA Carfrae, AA Fiebig-Comyn, BK Coombes, ... Nature communications 9 (1), 458, 2018 | 292 | 2018 |
Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains BK Coombes, ME Wickham, M Mascarenhas, S Gruenheid, BB Finlay, ... Applied Environmental Microbiology 74 (7), 2153-2160, 2008 | 248 | 2008 |
Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling EJ Culp, N Waglechner, W Wang, AA Fiebig-Comyn, YP Hsu, K Koteva, ... Nature 578 (7796), 582-587, 2020 | 245 | 2020 |
Expression and secretion of Salmonella pathogenicity island-2 virulence genes in response to acidification exhibit differential requirements of a functional type III secretion … BK Coombes, NF Brown, Y Valdez, JH Brumell, BB Finlay Journal of Biological Chemistry 279 (48), 49804-49815, 2004 | 228 | 2004 |
Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes JHE Nash, A Villegas, AM Kropinski, R Aguilar-Valenzuela, P Konczy, ... BMC Genomics 11 (1), 667, 2010 | 221 | 2010 |
Analysis of the contribution of Salmonella pathogenicity islands 1 and 2 to enteric disease progression using a novel bovine ileal loop model and a murine model of infectious … BK Coombes, BA Coburn, AA Potter, S Gomis, K Mirakhur, Y Li, BB Finlay Infection and Immunity 73 (11), 7161-7169, 2005 | 210 | 2005 |
Muramyl dipeptide-based postbiotics mitigate obesity-induced insulin resistance via IRF4 JF Cavallari, MD Fullerton, BM Duggan, KP Foley, E Denou, BK Smith, ... Cell metabolism 25 (5), 1063-1074. e3, 2017 | 202 | 2017 |
Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis CLN Small, SA Reid-Yu, JB McPhee, BK Coombes Nature communications 4 (1), 1957, 2013 | 186 | 2013 |
Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii G Liu, DB Catacutan, K Rathod, K Swanson, W Jin, JC Mohammed, ... Nature Chemical Biology 19 (11), 1342-1350, 2023 | 182 | 2023 |
Salmonella pathogenicity island 2 is expressed prior to penetrating the intestine NF Brown, BA Vallance, BK Coombes, Y Valdez, BA Coburn, BB Finlay PLoS Pathogens 1 (3), e32, 2005 | 171 | 2005 |
Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis MS Ladinsky, LP Araujo, X Zhang, J Veltri, M Galan-Diez, S Soualhi, ... Science 363 (6431), eaat4042, 2019 | 166 | 2019 |
FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling AA Ashkar, KL Mossman, BK Coombes, CL Gyles, R Mackenzie PLoS Pathogens 4 (12), e1000233, 2008 | 154 | 2008 |
Identification of MEK‐and phosphoinositide 3‐kinase‐dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells BK Coombes, JB Mahony Cellular Microbiology 4 (7), 447-460, 2002 | 147 | 2002 |
Chlamydia pneumoniae infection of human endothelial cells induces proliferation of smooth muscle cells via an endothelial cell-derived soluble factor (s) BK Coombes, JB Mahony Infection and Immunity 67 (6), 2909-2915, 1999 | 142 | 1999 |
Crossing the line: selection and evolution of virulence traits NF Brown, ME Wickham, BK Coombes, BB Finlay PLoS Pathogens 2 (5), e42, 2006 | 140 | 2006 |