Biosynthesis, total synthesis, and biological profiles of Ergot alkaloids NR Tasker, P Wipf The Alkaloids: Chemistry and Biology 85, 1-112, 2021 | 30 | 2021 |
A Short Synthesis of Ergot Alkaloids and Evaluation of the 5-HT1/2 Receptor Selectivity of Lysergols and Isolysergols NR Tasker, P Wipf Organic Letters 24 (40), 7255-7259, 2022 | 17 | 2022 |
Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors NR Tasker, EJ Rastelli, JC Burnett, ER Sharlow, JS Lazo, P Wipf Bioorganic & medicinal chemistry letters 29 (16), 2008-2015, 2019 | 14 | 2019 |
In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors NR Tasker, EJ Rastelli, IK Blanco, JC Burnett, ER Sharlow, JS Lazo, ... Organic & Biomolecular Chemistry 17 (9), 2448-2466, 2019 | 14 | 2019 |
Next-generation cell-active inhibitors of the undrugged oncogenic PTP4A3 phosphatase JS Lazo, IK Blanco, NR Tasker, EJ Rastelli, JC Burnett, SR Garrott, ... Journal of Pharmacology and Experimental Therapeutics 371 (3), 652-662, 2019 | 12 | 2019 |
Credentialing and pharmacologically targeting PTP4A3 phosphatase as a molecular target for ovarian cancer JS Lazo, ER Sharlow, R Cornelison, DJ Hart, DC Llaneza, AJ Mendelson, ... Biomolecules 11 (7), 969, 2021 | 9 | 2021 |
Structure of the complex of an iminopyridinedione protein tyrosine phosphatase 4a3 phosphatase inhibitor with human serum albumin MP Czub, AM Boulton, EJ Rastelli, NR Tasker, TS Maskrey, IK Blanco, ... Molecular Pharmacology 98 (6), 648-657, 2020 | 8 | 2020 |
Biological studies of clavine alkaloids targeting CNS receptors NR Tasker, EJ Pazur, P Wipf Frontiers in Psychiatry 14, 1286941, 2023 | 3 | 2023 |
Photoflow preparation of PTP4A3 inhibitors, and concise total syntheses of ergot and clavine alkaloids NR Tasker University of Pittsburgh, 2023 | 2 | 2023 |
Concise total syntheses of lysergene, lysergine, isolysergine and festuclavine NR Tasker, P Wipf ARKIVOC 2, S1-S13, 2024 | 1 | 2024 |
C3-Functionalization of indoles with α-heteroaryl-substituted methyl alcohols EJ Pazur, NR Tasker, P Wipf Organic & Biomolecular Chemistry 21 (43), 8651-8657, 2023 | 1 | 2023 |
Synthesis of Iso-Dimethyltryptamines and Biological Analysis in a Model of Light-Induced Retinal Degeneration E Pazur, N Tasker, K Vainionpää, A Kalatanova, H Leinonen, P Wipf | | 2024 |
Direct C3-functionalization of indoles with alpha-heteroaryl-substituted methyl alcohols via a metal-free hydrogen autotransfer-type reaction E Pazur, N Tasker, P Wipf | | 2023 |
Shortest Synthesis of Lysergol and its Binding to 5-HT1/2Receptors NR Tasker, P Wipf Synfacts 19 (01), 0109, 2023 | | 2023 |
In-flow photooxygenation of aminothienopyridinones generates novel ptp4a3 phosphatase inhibitors JS Lazo, E Sharlow, P Wipf, N Tasker, E Rastelli US Patent App. 17/309,259, 2022 | | 2022 |
In-flow photooxygenation of aminothienopyridinones generates novel ptp4a3 phosphatase inhibitors JS Lazo, E Sharlow, P Wipf, N Tasker, E Rastelli US Patent App. 17/309,260, 2021 | | 2021 |
Structure of the Complex of an Iminopyridinedione Protein Tyrosine Phosphatase 4A3 Phosphatase Inhibitor with Human Serum Albumin (vol 98, pg 648, 2020) MP Czub, AM Boulton, EJ Rastelli, NR Tasker, TS Maskrey, IK Blanco, ... MOLECULAR PHARMACOLOGY 98 (6), 781-781, 2020 | | 2020 |
Small molecule PTP4A3 phosphatase inhibitors targeting acute myeloid leukemia J Lazo, N Tasker, E Rastelli, P Wipf, E Sharlow European Journal of Cancer 138, S55-S56, 2020 | | 2020 |
Next Generation Potent Cell‐active Inhibitors of the Oncogenic PTP4A3 Phosphatase IK Blanco, NR Tasker, EJ Rastelli, P Wipf, ER Sharlow, JS Lazo The FASEB Journal 33 (S1), 674.11-674.11, 2019 | | 2019 |
The Mechanism of Inhibition of the Undrugged Oncogenic Phosphatase PTP4A3 by a Novel Small Molecule JMS‐053 SR Garrott, IK Blanco, NR Tasker, EJ Rastelli, ER Sharlow, P Wipf, ... The FASEB Journal 33 (S1), 674.14-674.14, 2019 | | 2019 |