| Maturation of autophagosomes and endosomes: a key role for Rab7 JMT Hyttinen, M Niittykoski, A Salminen, K Kaarniranta Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (3), 503-510, 2013 | 433 | 2013 |
| The role of NMDA and mGluR5 receptors in calcium mobilization and neurotoxicity of homocysteine in trigeminal and cortical neurons and glial cells PA Abushik, M Niittykoski, R Giniatullina, A Shakirzyanova, G Bart, ... Journal of neurochemistry 129 (2), 264-274, 2014 | 100 | 2014 |
| DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells—Implications for age-related macular degeneration (AMD) JMT Hyttinen, J Błasiak, M Niittykoski, K Kinnunen, A Kauppinen, ... Ageing Research Reviews 36, 64-77, 2017 | 75 | 2017 |
| The regulation of NFE2L2 (NRF2) signalling and epithelial-to-mesenchymal transition in age-related macular degeneration pathology JMT Hyttinen, R Kannan, S Felszeghy, M Niittykoski, A Salminen, ... International journal of molecular sciences 20 (22), 5800, 2019 | 53 | 2019 |
| The expression of heat shock protein 27 in retinal ganglion and glial cells in a rat glaucoma model G Kalesnykas, M Niittykoski, J Rantala, R Miettinen, A Salminen, ... Neuroscience 150 (3), 692-704, 2007 | 49 | 2007 |
| Clonal variation in interferon response determines the outcome of oncolytic virotherapy in mouse CT26 colon carcinoma model JJ Ruotsalainen, MU Kaikkonen, M Niittykoski, MW Martikainen, ... Gene therapy 22 (1), 65-75, 2015 | 38 | 2015 |
| MicroRNA-attenuated clone of virulent Semliki Forest virus overcomes antiviral type I interferon in resistant mouse CT-2A glioma M Martikainen, M Niittykoski, M von und zu Fraunberg, A Immonen, ... Journal of virology 89 (20), 10637-10647, 2015 | 37 | 2015 |
| Lack of uniformity in the mutational spectra of chlorohydroxyfuranones in Salmonella typhimurium strain TA100 JMT Hyttinen, M Niittykoski, K Jansson Mutagenesis 10 (4), 321-323, 1995 | 29 | 1995 |
| Interferon-β sensitivity of tumor cells correlates with poor response to VA7 virotherapy in mouse glioma models J Ruotsalainen, M Martikainen, M Niittykoski, T Huhtala, T Aaltonen, ... Molecular Therapy 20 (8), 1529-1539, 2012 | 28 | 2012 |
| Mutagenicity in vitro of 3,4‐dichloro‐5‐hydroxy‐2(5H)‐furanone (mucochloric acid), a chlorine disinfection by‐product in drinking water K Jansson, JMT Hyttinen, M Niittykoski, J Mäki‐Paakkanen Environmental and molecular mutagenesis 25 (4), 284-287, 1995 | 27 | 1995 |
| Altered calcium signaling in an experimental model of glaucoma M Niittykoski, G Kalesnykas, KP Larsson, K Kaarniranta, KEO Åkerman, ... Investigative ophthalmology & visual science 51 (12), 6387-6393, 2010 | 25 | 2010 |
| The initiation knot is a signaling center required for molar tooth development I Mogollón, JE Moustakas-Verho, M Niittykoski, L Ahtiainen Development 148 (9), dev194597, 2021 | 22 | 2021 |
| Activation of muscarinic M3-like receptors and β-adrenoceptors, but not M2-like muscarinic receptors or α-adrenoceptors, directly modulates corticostriatal neurotransmission in … M Niittykoski, S Ruotsalainen, A Haapalinna, J Larson, J Sirviö Neuroscience 90 (1), 95-105, 1999 | 21 | 1999 |
| Attenuated Semliki Forest virus for cancer treatment in dogs: safety assessment in two laboratory Beagles KPM Autio, JJ Ruotsalainen, MO Anttila, M Niittykoski, M Waris, ... BMC Veterinary Research 11, 1-9, 2015 | 18 | 2015 |
| Unusually strong temperature dependence of P2X3 receptor traffic to the plasma membrane E Pryazhnikov, D Fayuk, M Niittykoski, R Giniatullin, L Khiroug Frontiers in Cellular Neuroscience 5, 27, 2011 | 17 | 2011 |
| Electrophysiologic changes in the lateral and basal amygdaloid nuclei in temporal lobe epilepsy: an in vitro study in epileptic rats M Niittykoski, J Nissinen, M Penttonen, A Pitkänen Neuroscience 124 (2), 269-281, 2004 | 14 | 2004 |
| Diminution of N-methyl-D-aspartate-induced perturbation of neurotransmission by dexmedetomidine in the CA1 field of rat hippocampus in vitro M Niittykoski, A Haapalinna, J Sirviö Neuroscience letters 281 (2-3), 95-98, 2000 | 14 | 2000 |
| Systemic administration of atipamezole, an α2-antagonist, can reduce scopolamine-induced hyperactivity in rats M Niittykoski, V Hakkarainen, T Puumala, R Lappalainen, S Ruotsalainen, ... Behavioural pharmacology 8 (5), 465-470, 1997 | 13 | 1997 |
| Systemic administration of atipamezole, a selective antagonist of alpha-2 adrenoceptors, facilitates behavioural activity but does not influence short-term or long-term memory … M Niittykoski, R Lappalainen, J Jolkkonen, A Haapalinna, P Riekkinen Sr, ... Neuroscience & Biobehavioral Reviews 22 (6), 735-750, 1998 | 12 | 1998 |
| Salmonella and mammalian-cell mutagenicity of 3-chloro-4-(chloromethyl)-5-hydroxy-2 (5H)-furanone M Niittykoski, JMT Hyttinen, K Jansson Mutation Research Letters 348 (1), 51-55, 1995 | 12 | 1995 |
Antti HaapalinnaVice President R&D,Head of External Research and PartneringVerified email at orionpharma.com
