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Maximilian Helf
Maximilian Helf
Principal Scientist at NIBR
Verified email at cornell.edu
Title
Cited by
Cited by
Year
An environmental bacterial taxon with a large and distinct metabolic repertoire
MC Wilson, T Mori, C Rückert, AR Uria, MJ Helf, K Takada, C Gernert, ...
Nature 506 (7486), 58-62, 2014
6172014
Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides
MF Freeman, C Gurgui, MJ Helf, BI Morinaka, AR Uria, NJ Oldham, ...
Science 338 (6105), 387-390, 2012
3802012
Radical S‐Adenosyl Methionine Epimerases: Regioselective Introduction of Diverse D‐Amino Acid Patterns into Peptide Natural Products
BI Morinaka, AL Vagstad, MJ Helf, M Gugger, C Kegler, MF Freeman, ...
Angewandte Chemie International Edition 53 (32), 8503-8507, 2014
127*2014
Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium
MF Freeman, MJ Helf, A Bhushan, BI Morinaka, J Piel
Nature chemistry 9 (4), 387-395, 2017
1222017
Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products
NS Van Der Velden, N Kälin, MJ Helf, J Piel, MF Freeman, M Künzler
Nature chemical biology 13 (8), 833-835, 2017
1182017
Natural noncanonical protein splicing yields products with diverse β-amino acid residues
BI Morinaka, E Lakis, M Verest, MJ Helf, T Scalvenzi, AL Vagstad, J Sims, ...
Science 359 (6377), 779-782, 2018
932018
A practical guide to metabolomics software development
HY Chang, SM Colby, X Du, JD Gomez, MJ Helf, K Kechris, ...
Analytical chemistry 93 (4), 1912-1923, 2021
402021
Comparative metabolomics with Metaboseek reveals functions of a conserved fat metabolism pathway in C. elegans
MJ Helf, BW Fox, AB Artyukhin, YK Zhang, FC Schroeder
Nature Communications 13 (1), 782, 2022
252022
Deep interrogation of metabolism using a pathway-targeted click-chemistry approach
JS Hoki, HH Le, KE Mellott, YK Zhang, BW Fox, PR Rodrigues, Y Yu, ...
Journal of the American Chemical Society 142 (43), 18449-18459, 2020
202020
Enzyme from an uncultivated sponge bacterium catalyzes s‐methylation in a ribosomal peptide
MJ Helf, A Jud, J Piel
ChemBioChem 18 (5), 444-450, 2017
182017
Modular metabolite assembly in Caenorhabditis elegans depends on carboxylesterases and formation of lysosome-related organelles
HH Le, CJJ Wrobel, SM Cohen, J Yu, H Park, MJ Helf, BJ Curtis, ...
Elife 9, e61886, 2020
172020
Investigations into PoyH, a promiscuous protease from polytheonamide biosynthesis
MJ Helf, MF Freeman, J Piel
Journal of Industrial Microbiology and Biotechnology 46 (3-4), 551-563, 2019
142019
Modular metabolite assembly in C. elegans lysosome-related organelles
HH Le, CJJ Wrobel, SM Cohen, J Yu, H Park, MJ Helf, BJ Curtis, ...
BioRxiv, in press.[Europe PMC free article][Abstract][Google Scholar], 2020
22020
Biosynthetic gene cluster for the production of peptide/protein analogues
J Piel, C Gurgui, MF Freeman, AR Uria, MJ Helf
US Patent App. 14/342,539, 2014
22014
Evolutionarily related host and microbial pathways regulate fat desaturation in C. elegans
BW Fox, MJ Helf, RN Burkhardt, AB Artyukhin, BJ Curtis, DF Palomino, ...
Nature Communications 15 (1), 1-15, 2024
2024
Evolutionarily related host and microbial pathways regulate fat desaturation
BW Fox, MJ Helf, RN Burkhardt, AB Artyukhin, BJ Curtis, DF Palomino, ...
bioRxiv, 2023
2023
Exploring the proteusin family of unusual ribosomal peptide natural products
MJ Helf
ETH Zurich, 2015
2015
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