An environmental bacterial taxon with a large and distinct metabolic repertoire MC Wilson, T Mori, C Rückert, AR Uria, MJ Helf, K Takada, C Gernert, ... Nature 506 (7486), 58-62, 2014 | 617 | 2014 |
Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides MF Freeman, C Gurgui, MJ Helf, BI Morinaka, AR Uria, NJ Oldham, ... Science 338 (6105), 387-390, 2012 | 380 | 2012 |
Radical S‐Adenosyl Methionine Epimerases: Regioselective Introduction of Diverse D‐Amino Acid Patterns into Peptide Natural Products BI Morinaka, AL Vagstad, MJ Helf, M Gugger, C Kegler, MF Freeman, ... Angewandte Chemie International Edition 53 (32), 8503-8507, 2014 | 127* | 2014 |
Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium MF Freeman, MJ Helf, A Bhushan, BI Morinaka, J Piel Nature chemistry 9 (4), 387-395, 2017 | 122 | 2017 |
Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products NS Van Der Velden, N Kälin, MJ Helf, J Piel, MF Freeman, M Künzler Nature chemical biology 13 (8), 833-835, 2017 | 118 | 2017 |
Natural noncanonical protein splicing yields products with diverse β-amino acid residues BI Morinaka, E Lakis, M Verest, MJ Helf, T Scalvenzi, AL Vagstad, J Sims, ... Science 359 (6377), 779-782, 2018 | 93 | 2018 |
A practical guide to metabolomics software development HY Chang, SM Colby, X Du, JD Gomez, MJ Helf, K Kechris, ... Analytical chemistry 93 (4), 1912-1923, 2021 | 40 | 2021 |
Comparative metabolomics with Metaboseek reveals functions of a conserved fat metabolism pathway in C. elegans MJ Helf, BW Fox, AB Artyukhin, YK Zhang, FC Schroeder Nature Communications 13 (1), 782, 2022 | 25 | 2022 |
Deep interrogation of metabolism using a pathway-targeted click-chemistry approach JS Hoki, HH Le, KE Mellott, YK Zhang, BW Fox, PR Rodrigues, Y Yu, ... Journal of the American Chemical Society 142 (43), 18449-18459, 2020 | 20 | 2020 |
Enzyme from an uncultivated sponge bacterium catalyzes s‐methylation in a ribosomal peptide MJ Helf, A Jud, J Piel ChemBioChem 18 (5), 444-450, 2017 | 18 | 2017 |
Modular metabolite assembly in Caenorhabditis elegans depends on carboxylesterases and formation of lysosome-related organelles HH Le, CJJ Wrobel, SM Cohen, J Yu, H Park, MJ Helf, BJ Curtis, ... Elife 9, e61886, 2020 | 17 | 2020 |
Investigations into PoyH, a promiscuous protease from polytheonamide biosynthesis MJ Helf, MF Freeman, J Piel Journal of Industrial Microbiology and Biotechnology 46 (3-4), 551-563, 2019 | 14 | 2019 |
Modular metabolite assembly in C. elegans lysosome-related organelles HH Le, CJJ Wrobel, SM Cohen, J Yu, H Park, MJ Helf, BJ Curtis, ... BioRxiv, in press.[Europe PMC free article][Abstract][Google Scholar], 2020 | 2 | 2020 |
Biosynthetic gene cluster for the production of peptide/protein analogues J Piel, C Gurgui, MF Freeman, AR Uria, MJ Helf US Patent App. 14/342,539, 2014 | 2 | 2014 |
Evolutionarily related host and microbial pathways regulate fat desaturation in C. elegans BW Fox, MJ Helf, RN Burkhardt, AB Artyukhin, BJ Curtis, DF Palomino, ... Nature Communications 15 (1), 1-15, 2024 | | 2024 |
Evolutionarily related host and microbial pathways regulate fat desaturation BW Fox, MJ Helf, RN Burkhardt, AB Artyukhin, BJ Curtis, DF Palomino, ... bioRxiv, 2023 | | 2023 |
Exploring the proteusin family of unusual ribosomal peptide natural products MJ Helf ETH Zurich, 2015 | | 2015 |