| SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging W Rut, K Groborz, L Zhang, X Sun, M Zmudzinski, B Pawlik, X Wang, ... Nature chemical biology 17 (2), 222-228, 2021 | 233 | 2021 |
| Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1 MLG Ramirez, M Poreba, SJ Snipas, K Groborz, M Drag, GS Salvesen Journal of Biological Chemistry 293 (18), 7058-7067, 2018 | 81 | 2018 |
| Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes M Poreba, W Rut, M Vizovisek, K Groborz, P Kasperkiewicz, D Finlay, ... Chemical Science 9 (8), 2113-2129, 2018 | 69 | 2018 |
| Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples M Poreba, K Groborz, M Vizovisek, M Maruggi, D Turk, B Turk, G Powis, ... Chemical science 10 (36), 8461-8477, 2019 | 56 | 2019 |
| Emerging challenges in the design of selective substrates, inhibitors and activity‐based probes for indistinguishable proteases P Kasperkiewicz, M Poreba, K Groborz, M Drag The FEBS journal 284 (10), 1518-1539, 2017 | 52 | 2017 |
| Caspase selective reagents for diagnosing apoptotic mechanisms M Poreba, K Groborz, M Navarro, SJ Snipas, M Drag, GS Salvesen Cell Death & Differentiation 26 (2), 229-244, 2019 | 50 | 2019 |
| Substrate specificity profiling of SARS-CoV-2 Mpro protease provides basis for anti-COVID-19 drug design W Rut, K Groborz, L Zhang, X Sun, M Zmudzinski, R Hilgenfeld, M Drag BioRxiv, 2020 | 47 | 2020 |
| Multiplexed probing of proteolytic enzymes using mass cytometry-compatible activity-based probes M Poreba, KM Groborz, W Rut, M Pore, SJ Snipas, M Vizovisek, B Turk, ... Journal of the American Chemical Society 142 (39), 16704-16715, 2020 | 33 | 2020 |
| Substrate specificity profiling of SARS-CoV-2 main protease enables design of activity-based probes for patient-sample imaging W Rut, K Groborz, L Zhang, X Sun, M Zmudzinski, B Pawlik, W Młynarski, ... Biorxiv, 2020.03. 07.981928, 2020 | 24 | 2020 |
| Recent advances and concepts in substrate specificity determination of proteases using tailored libraries of fluorogenic substrates with unnatural amino acids W Rut, P Kasperkiewicz, A Byzia, M Poreba, K Groborz, M Drag Biological Chemistry 396 (4), 329-337, 2015 | 24 | 2015 |
| Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells M Poreba, W Rut, K Groborz, SJ Snipas, GS Salvesen, M Drag Cell Death & Differentiation 26 (12), 2695-2709, 2019 | 23 | 2019 |
| Design of Optical‐Imaging Probes by Screening of Diverse Substrate Libraries Directly in Disease‐Tissue Extracts M Tholen, JJ Yim, K Groborz, E Yoo, BA Martin, NS van den Berg, M Drag, ... Angewandte Chemie International Edition 59 (43), 19143-19152, 2020 | 20 | 2020 |
| Profiling of flaviviral NS2B-NS3 protease specificity provides a structural basis for the development of selective chemical tools that differentiate Dengue from Zika and West … W Rut, K Groborz, L Zhang, S Modrzycka, M Poreba, R Hilgenfeld, M Drag Antiviral Research 175, 104731, 2020 | 17 | 2020 |
| Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes P Kasperkiewicz, S Kołt, T Janiszewski, K Groborz, M Poręba, SJ Snipas, ... Scientific reports 8 (1), 15998, 2018 | 15 | 2018 |
| Internally quenched fluorogenic substrates with unnatural amino acids for cathepsin G investigation K Groborz, S Kołt, P Kasperkiewicz, M Drag Biochimie 166, 103-111, 2019 | 12 | 2019 |
| Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells K Groborz, ML Gonzalez Ramirez, SJ Snipas, GS Salvesen, M Drąg, ... Cell Death & Differentiation 27 (2), 451-465, 2020 | 9 | 2020 |
| Cytotoxicity, early safety screening, and antimicrobial potential of minor oxime constituents of essential oils and aromatic extracts AK Surowiak, M Sowała, M Talma, K Groborz, L Balcerzak, S Lochyński, ... Scientific Reports 12 (1), 5319, 2022 | 7 | 2022 |
| Structural Determinants of Substrate Specificity of SplF Protease from Staphylococcus aureus N Stach, A Karim, P Golik, R Kitel, K Pustelny, N Gruba, K Groborz, ... International journal of molecular sciences 22 (4), 2220, 2021 | 7 | 2021 |
| Development of an advanced nanoformulation for the intracellular delivery of a caspase-3 selective activity-based probe F Cogo, M Poreba, W Rut, K Groborz, P Smyth, MC Johnston, R Williams, ... Nanoscale 11 (2), 742-751, 2019 | 6 | 2019 |
| Selective chemical reagents to investigate the role of caspase 6 in apoptosis in acute leukemia T cells KM Groborz, M Kalinka, J Grzymska, S Kołt, SJ Snipas, M Poręba Chemical Science 14 (9), 2289-2302, 2023 | 3 | 2023 |
