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Balint Kintses
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Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics
PY Colin, B Kintses, F Gielen, CM Miton, G Fischer, MF Mohamed, ...
Nature communications 6 (1), 1-12, 2015
2362015
Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides
V Lázár, A Martins, R Spohn, L Daruka, G Grézal, G Fekete, M Számel, ...
Nature microbiology 3 (6), 718-731, 2018
2352018
Picoliter cell lysate assays in microfluidic droplet compartments for directed enzyme evolution
B Kintses, C Hein, MF Mohamed, M Fischlechner, F Courtois, C Lainé, ...
Chemistry & biology 19 (8), 1001-1009, 2012
2302012
Microfluidic droplets: new integrated workflows for biological experiments
B Kintses, LD van Vliet, SRA Devenish, F Hollfelder
Current opinion in chemical biology 14 (5), 548-555, 2010
2082010
One in a million: flow cytometric sorting of single cell-lysate assays in monodisperse picolitre double emulsion droplets for directed evolution
A Zinchenko, SRA Devenish, B Kintses, PY Colin, M Fischlechner, ...
Analytical chemistry 86 (5), 2526-2533, 2014
2002014
Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance
R Spohn, L Daruka, V Lázár, A Martins, F Vidovics, G Grézal, O Méhi, ...
Nature communications 10 (1), 1-13, 2019
1592019
Network-level architecture and the evolutionary potential of underground metabolism
RA Notebaart, B Szappanos, B Kintses, F Pál, Á Györkei, B Bogos, ...
Proceedings of the National Academy of Sciences 111 (32), 11762-11767, 2014
1082014
A novel actin binding site of myosin required for effective muscle contraction
BH Várkuti, Z Yang, B Kintses, P Erdélyi, I Bárdos-Nagy, AL Kovács, ...
Nature structural & molecular biology 19 (3), 299-306, 2012
692012
Reversible movement of switch 1 loop of myosin determines actin interaction
B Kintses, M Gyimesi, DS Pearson, MA Geeves, W Zeng, CR Bagshaw, ...
The EMBO journal 26 (1), 265-274, 2007
662007
Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance
Á Nyerges, B Csörgő, G Draskovits, B Kintses, P Szili, G Ferenc, T Révész, ...
Proceedings of the National Academy of Sciences 115 (25), E5726-E5735, 2018
652018
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke
B Takács, N Billington, M Gyimesi, B Kintses, A Málnási-Csizmadia, ...
Proceedings of the National Academy of Sciences 107 (15), 6799-6804, 2010
652010
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II
M Gyimesi, B Kintses, A Bodor, A Perczel, S Fischer, CR Bagshaw, ...
Journal of Biological Chemistry 283 (13), 8153-8163, 2008
642008
Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota
B Kintses, O Méhi, E Ari, M Számel, Á Györkei, PK Jangir, I Nagy, F Pál, ...
Nature microbiology 4 (3), 447-458, 2019
492019
Underground metabolism: network-level perspective and biotechnological potential
RA Notebaart, B Kintses, AM Feist, B Papp
Current Opinion in Biotechnology 49, 108-114, 2018
432018
Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins
E Natan, T Endoh, L Haim-Vilmovsky, T Flock, G Chalancon, JTS Hopper, ...
Nature structural & molecular biology 25 (3), 279-288, 2018
352018
Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset
CM Miton, S Jonas, G Fischer, F Duarte, MF Mohamed, B van Loo, ...
Proceedings of the National Academy of Sciences 115 (31), E7293-E7302, 2018
282018
Experimental investigation of the seesaw mechanism of the relay region that moves the myosin lever arm
B Kintses, Z Yang, A Málnási-Csizmadia
Journal of Biological Chemistry 283 (49), 34121-34128, 2008
282008
Enzyme kinetics above denaturation temperature: a temperature-jump/stopped-flow apparatus
B Kintses, Z Simon, M Gyimesi, J Tóth, B Jelinek, C Niedetzky, M Kovács, ...
Biophysical journal 91 (12), 4605-4610, 2006
232006
Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action
B Kintses, PK Jangir, G Fekete, M Számel, O Méhi, R Spohn, L Daruka, ...
Nature communications 10 (1), 1-13, 2019
212019
Rapid evolution of reduced susceptibility against a balanced dual-targeting antibiotic through stepping-stone mutations
P Szili, G Draskovits, T Révész, F Bogár, D Balogh, T Martinek, L Daruka, ...
Antimicrobial agents and chemotherapy 63 (9), e00207-19, 2019
182019
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