David J Irwin
David J Irwin
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Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria
GU Höglinger, G Respondek, M Stamelou, C Kurz, KA Josephs, AE Lang, ...
Movement disorders 32 (6), 853-864, 2017
Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis
J Brettschneider, K Del Tredici, JB Toledo, JL Robinson, DJ Irwin, ...
Annals of neurology 74 (1), 20-38, 2013
Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
DJ Irwin, VMY Lee, JQ Trojanowski
Nature Reviews Neuroscience 14 (9), 626-636, 2013
Neuropathologic substrates of Parkinson disease dementia
DJ Irwin, MT White, JB Toledo, SX Xie, JL Robinson, V Van Deerlin, ...
Annals of neurology 72 (4), 587-598, 2012
Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated
JL Robinson, EB Lee, SX Xie, L Rennert, ER Suh, C Bredenberg, ...
Brain 141 (7), 2181-2193, 2018
Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
DJ Irwin, M Grossman, D Weintraub, HI Hurtig, JE Duda, SX Xie, EB Lee, ...
The Lancet Neurology 16 (1), 55-65, 2017
Association of cerebrospinal fluid β-amyloid 1-42, T-tau, P-tau181, and α-synuclein levels with clinical features of drug-naive patients with early Parkinson disease
JH Kang, DJ Irwin, AS Chen-Plotkin, A Siderowf, C Caspell, CS Coffey, ...
JAMA neurology 70 (10), 1277-1287, 2013
APOE ϵ4 increases risk for dementia in pure synucleinopathies
D Tsuang, JB Leverenz, OL Lopez, RL Hamilton, DA Bennett, ...
JAMA neurology 70 (2), 223-228, 2013
SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network
J Hu, X Li, K Coleman, A Schroeder, N Ma, DJ Irwin, EB Lee, ...
Nature methods 18 (11), 1342-1351, 2021
Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
DJ Irwin, TJ Cohen, M Grossman, SE Arnold, SX Xie, VMY Lee, ...
Brain 135 (3), 807-818, 2012
Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD)
J Brettschneider, K Del Tredici, DJ Irwin, M Grossman, JL Robinson, ...
Acta neuropathologica 127, 423-439, 2014
Positron emission tomography imaging with [18F] flortaucipir and postmortem assessment of Alzheimer disease neuropathologic changes
AS Fleisher, MJ Pontecorvo, MD Devous, M Lu, AK Arora, SP Truocchio, ...
JAMA neurology 77 (7), 829-839, 2020
Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine
DJ Irwin, NJ Cairns, M Grossman, CT McMillan, EB Lee, VM Van Deerlin, ...
Acta neuropathologica 129, 469-491, 2015
Distribution patterns of tau pathology in progressive supranuclear palsy
GG Kovacs, MJ Lukic, DJ Irwin, T Arzberger, G Respondek, EB Lee, ...
Acta neuropathologica 140, 99-119, 2020
TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord
J Brettschneider, K Arai, K Del Tredici, JB Toledo, JL Robinson, EB Lee, ...
Acta neuropathologica 128, 423-437, 2014
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study
KM Moore, J Nicholas, M Grossman, CT McMillan, DJ Irwin, L Massimo, ...
The Lancet Neurology 19 (2), 145-156, 2020
Tauopathies as clinicopathological entities
DJ Irwin
Parkinsonism & related disorders 22, S29-S33, 2016
C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD
EY Liu, J Russ, K Wu, D Neal, E Suh, AG McNally, DJ Irwin, ...
Acta neuropathologica 128, 525-541, 2014
Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion
J Brettschneider, VM Van Deerlin, JL Robinson, L Kwong, EB Lee, YO Ali, ...
Acta neuropathologica 123, 825-839, 2012
Expansion of the classification of FTLD-TDP: distinct pathology associated with rapidly progressive frontotemporal degeneration
EB Lee, S Porta, G Michael Baer, Y Xu, ER Suh, LK Kwong, L Elman, ...
Acta neuropathologica 134, 65-78, 2017
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