| α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B DG Ferreira, M Temido-Ferreira, H Vicente Miranda, VL Batalha, ... Nature neuroscience 20 (11), 1569-1579, 2017 | 276 | 2017 |
| Meningeal γδ T cell–derived IL-17 controls synaptic plasticity and short-term memory M Ribeiro, HC Brigas, M Temido-Ferreira, PA Pousinha, T Regen, ... Science immunology 4 (40), eaay5199, 2019 | 242 | 2019 |
| Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms L Yu, HY Shen, JE Coelho, IM Araújo, QY Huang, YJ Day, N Rebola, ... Annals of neurology 63 (3), 338-346, 2008 | 189 | 2008 |
| A2A adenosine receptor deletion is protective in a mouse model of Tauopathy C Laurent, S Burnouf, B Ferry, VL Batalha, JE Coelho, Y Baqi, E Malik, ... Molecular psychiatry 21 (1), 97-107, 2016 | 183 | 2016 |
| A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A … HY Shen, JE Coelho, N Ohtsuka, PM Canas, YJ Day, QY Huang, ... Journal of Neuroscience 28 (12), 2970-2975, 2008 | 183 | 2008 |
| Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors M Temido-Ferreira, DG Ferreira, VL Batalha, I Marques-Morgado, ... Molecular psychiatry 25 (8), 1876-1900, 2020 | 170 | 2020 |
| Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats N Rebola, JE Coelho, AR Costenla, LV Lopes, A Parada, CR Oliveira, ... European Journal of Neuroscience 18 (4), 820-828, 2003 | 142 | 2003 |
| IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease HC Brigas, M Ribeiro, JE Coelho, R Gomes, V Gomez-Murcia, K Carvalho, ... Cell reports 36 (9), 2021 | 123 | 2021 |
| A novel resistance mechanism to triclosan that suggests horizontal gene transfer and demonstrates a potential selective pressure for reduced biocide susceptibility in clinical … ML Ciusa, L Furi, D Knight, F Decorosi, M Fondi, C Raggi, JR Coelho, ... International journal of antimicrobial agents 40 (3), 210-220, 2012 | 123 | 2012 |
| Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety JE Coelho, P Alves, PM Canas, JS Valadas, T Shmidt, VL Batalha, ... Frontiers in psychiatry 5, 67, 2014 | 119 | 2014 |
| Selective inactivation of adenosine A2A receptors in striatal neurons enhances working memory and reversal learning CJ Wei, P Singer, J Coelho, D Boison, J Feldon, BK Yee, JF Chen Learning & memory 18 (7), 459-474, 2011 | 110 | 2011 |
| Adenosine A2A receptors control the extracellular levels of adenosine through modulation of nucleoside transporters activity in the rat hippocampus A Pinto‐Duarte, JE Coelho, RA Cunha, JA Ribeiro, AM Sebastiao Journal of neurochemistry 93 (3), 595-604, 2005 | 109 | 2005 |
| Adenosine A2A Receptors Modulate α-Synuclein Aggregation and Toxicity DG Ferreira, VL Batalha, H Vicente Miranda, JE Coelho, R Gomes, ... Cerebral Cortex 27 (1), 718-730, 2017 | 101 | 2017 |
| Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease E Faivre, JE Coelho, K Zornbach, E Malik, Y Baqi, M Schneider, L Cellai, ... Frontiers in molecular neuroscience 11, 235, 2018 | 87 | 2018 |
| Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus JE Coelho, N Rebola, I Fragata, JA Ribeiro, A De Mendonça, RA Cunha Neuroscience 138 (4), 1195-1203, 2006 | 87 | 2006 |
| Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor K Carvalho, E Faivre, MJ Pietrowski, X Marques, V Gomez-Murcia, ... Brain 142 (11), 3636-3654, 2019 | 85 | 2019 |
| Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains G Bai, I Cheung, HP Shulha, JE Coelho, P Li, X Dong, M Jakovcevski, ... Human molecular genetics 24 (5), 1441-1456, 2015 | 84 | 2015 |
| Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A2A receptor knockout mice with microarray profiling L Yu, JE Coelho, X Zhang, Y Fu, A Tillman, U Karaoz, BB Fredholm, ... Physiological genomics 37 (3), 199-210, 2009 | 68 | 2009 |
| The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function VL Batalha, DG Ferreira, JE Coelho, JS Valadas, R Gomes, ... Scientific Reports 6 (1), 31493, 2016 | 65 | 2016 |
| From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease? V Flaten, C Laurent, JE Coelho, U Sandau, VL Batalha, S Burnouf, ... Biochemical Society Transactions 42 (2), 587-592, 2014 | 61 | 2014 |
