Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways H Ichijo, E Nishida, K Irie, P Dijke, M Saitoh, T Moriguchi, M Takagi, ... Science 275 (5296), 90-94, 1997 | 2829 | 1997 |
Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction K Yamaguchi, K Shirakabe, H Shibuya, K Irie, I Oishi, N Ueno, ... Science 270 (5244), 2008-2011, 1995 | 1708 | 1995 |
TAB1: an activator of the TAK1 MAPKKK in TGF-β signal transduction H Shibuya, K Yamaguchi, K Shirakabe, A Tonegawa, Y Gotoh, N Ueno, ... Science 272 (5265), 1179-1182, 1996 | 803 | 1996 |
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway G Takaesu, S Kishida, A Hiyama, K Yamaguchi, H Shibuya, K Irie, ... Molecular cell 5 (4), 649-658, 2000 | 752 | 2000 |
A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase … T Mizoguchi, K Irie, T Hirayama, N Hayashida, K Yamaguchi-Shinozaki, ... Proceedings of the National Academy of Sciences 93 (2), 765-769, 1996 | 636 | 1996 |
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3 T Moriguchi, N Kuroyanagi, K Yamaguchi, Y Gotoh, K Irie, T Kano, ... Journal of Biological Chemistry 271 (23), 13675-13679, 1996 | 588 | 1996 |
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1–TAK1 in the BMP signaling pathway K Yamaguchi, S Nagai, J Ninomiya-Tsuji, M Nishita, K Tamai, K Irie, ... The EMBO journal 18 (1), 179-187, 1999 | 525 | 1999 |
A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C KS Lee, K Irie, Y Gotoh, Y Watanabe, H Araki, E Nishida, K Matsumoto, ... Molecular and cellular biology 13 (5), 3067-3075, 1993 | 486 | 1993 |
The oncoprotein Evi-1 represses TGF-β signalling by inhibiting Smad3 M Kurokawa, K Mitani, K Irie, T Matsuyama, T Takahashi, S Chiba, ... Nature 394 (6688), 92-96, 1998 | 440 | 1998 |
TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase K Shirakabe, K Yamaguchi, H Shibuya, K Irie, S Matsuda, T Moriguchi, ... Journal of Biological Chemistry 272 (13), 8141-8144, 1997 | 433 | 1997 |
MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C K Irie, M Takase, KS Lee, DE Levin, H Araki, K Matsumoto, Y Oshima Molecular and cellular biology, 1993 | 387 | 1993 |
Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase K Irie, Y Gotoh, BM Yashar, B Errede, E Nishida, K Matsumoto Science 265 (5179), 1716-1719, 1994 | 374 | 1994 |
Nectins and nectin‐like molecules: roles in cell adhesion, migration, and polarization Y Takai, K Irie, K Shimizu, T Sakisaka, W Ikeda Cancer science 94 (8), 655-667, 2003 | 364 | 2003 |
Role of TAK1 and TAB1 in BMP signaling in early Xenopus development H Shibuya, H Iwata, N Masuyama, Y Gotoh, K Yamaguchi, K Irie, ... The EMBO Journal, 1998 | 296 | 1998 |
Yeast RLM1 Encodes a Serum Response Factor-Like Protein That May Function Downstream of the Mpk1 (Slt2) Mitogen-Activated Protein Kinase Pathway Y Watanabe, K Irie, K Matsumoto Molecular and cellular biology 15 (10), 5740-5749, 1995 | 271 | 1995 |
Nectin couples cell-cell adhesion and the actin scaffold at heterotypic testicular junctions K Ozaki-Kuroda, H Nakanishi, H Ohta, H Tanaka, H Kurihara, S Mueller, ... Current Biology 12 (13), 1145-1150, 2002 | 269 | 2002 |
Isolation of ATMEKK1 (a MAP Kinase Kinase Kinase)-Interacting Proteins and Analysis of a MAP Kinase Cascade inArabidopsis K Ichimura, T Mizoguchi, K Irie, P Morris, J Giraudat, K Matsumoto, ... Biochemical and biophysical research communications 253 (2), 532-543, 1998 | 254 | 1998 |
Expansion of the cell plate in plant cytokinesis requires a kinesin-like protein/MAPKKK complex R Nishihama, T Soyano, M Ishikawa, S Araki, H Tanaka, T Asada, K Irie, ... Cell 109 (1), 87-99, 2002 | 249 | 2002 |
Characterization of a Serum Response Factor-Like Protein in Saccharomyces cerevisiae, Rlm1, Which Has Transcriptional Activity Regulated by the Mpk1 (Slt2 … Y Watanabe, G Takaesu, M Hagiwara, K Irie, K Matsumoto Molecular and cellular biology 17 (5), 2615-2623, 1997 | 248 | 1997 |
p38 Mitogen-Activated Protein Kinase Can Be Involved in Transforming Growth Factor β Superfamily Signal Transduction in Drosophila Wing Morphogenesis T Adachi-Yamada, M Nakamura, K Irie, Y Tomoyasu, Y Sano, E Mori, ... Molecular and cellular biology 19 (3), 2322-2329, 1999 | 211 | 1999 |