Diverse relations between ABC transporters and lipids: An overview J Neumann, D Rose-Sperling, UA Hellmich Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (4), 605-618, 2017 | 157 | 2017 |
Phosphatidylinositol-4, 5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli A Garcia-Elias, S Mrkonjić, C Pardo-Pastor, H Inada, UA Hellmich, ... Proceedings of the National Academy of Sciences 110 (23), 9553-9558, 2013 | 140 | 2013 |
Comparison of mechanistic transport cycle models of ABC exporters D Szöllősi, D Rose-Sperling, UA Hellmich, T Stockner Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (4), 818-832, 2018 | 113 | 2018 |
Structural biology of TRP channels UA Hellmich, R Gaudet Mammalian Transient Receptor Potential (TRP) Cation Channels: Volume II, 963-990, 2014 | 106 | 2014 |
Quantum chemical-based protocol for the rational design of covalent inhibitors T Schirmeister, J Kesselring, S Jung, TH Schneider, A Weickert, J Becker, ... Journal of the American Chemical Society 138 (27), 8332-8335, 2016 | 77 | 2016 |
Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus A Zutz, J Hoffmann, UA Hellmich, C Glaubitz, B Ludwig, B Brutschy, ... Journal of biological chemistry 286 (9), 7104-7115, 2011 | 74 | 2011 |
Proline-based allosteric inhibitors of Zika and Dengue virus NS2B/NS3 proteases B Millies, F von Hammerstein, A Gellert, S Hammerschmidt, F Barthels, ... Journal of Medicinal Chemistry 62 (24), 11359-11382, 2019 | 73 | 2019 |
Solid-state NMR and functional studies on proteorhodopsin N Pfleger, AC Wörner, J Yang, S Shastri, UA Hellmich, L Aslimovska, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (6), 697-705, 2009 | 67 | 2009 |
Probing the ATP hydrolysis cycle of the ABC multidrug transporter LmrA by pulsed EPR spectroscopy UA Hellmich, S Lyubenova, E Kaltenborn, R Doshi, HW van Veen, ... Journal of the American Chemical Society 134 (13), 5857-5862, 2012 | 64 | 2012 |
Dipeptidyl nitroalkenes as potent reversible inhibitors of cysteine proteases rhodesain and cruzain A Latorre, T Schirmeister, J Kesselring, S Jung, P Johe, UA Hellmich, ... ACS medicinal chemistry letters 7 (12), 1073-1076, 2016 | 60 | 2016 |
Development of novel peptide-based Michael acceptors targeting rhodesain and falcipain-2 for the treatment of Neglected Tropical Diseases (NTDs) S Previti, R Ettari, S Cosconati, G Amendola, K Chouchene, A Wagner, ... Journal of Medicinal Chemistry 60 (16), 6911-6923, 2017 | 56 | 2017 |
Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR SJ Ullrich, UA Hellmich, S Ullrich, C Glaubitz Nature chemical biology 7 (5), 263-270, 2011 | 53 | 2011 |
Essential ribosome assembly factor Fap7 regulates a hierarchy of RNA–protein interactions during small ribosomal subunit biogenesis UA Hellmich, BL Weis, A Lioutikov, JP Wurm, M Kaiser, NA Christ, ... Proceedings of the National Academy of Sciences 110 (38), 15253-15258, 2013 | 41 | 2013 |
19F NMR as a versatile tool to study membrane protein structure and dynamics D Rose-Sperling, MA Tran, LM Lauth, B Goretzki, UA Hellmich Biological chemistry 400 (10), 1277-1288, 2019 | 39 | 2019 |
The solution structure of the lantibiotic immunity protein NisI and its interactions with nisin C Hacker, NA Christ, E Duchardt-Ferner, S Korn, C Göbl, L Berninger, ... Journal of Biological Chemistry 290 (48), 28869-28886, 2015 | 37 | 2015 |
NMR and EPR studies of membrane transporters UA Hellmich, C Glaubitz Walter de Gruyter 390 (8), 815-834, 2009 | 35 | 2009 |
Structural basis of TRPV4 N terminus interaction with syndapin/PACSIN1-3 and PIP2 B Goretzki, NA Glogowski, E Diehl, E Duchardt-Ferner, C Hacker, ... Structure 26 (12), 1583-1593. e5, 2018 | 33 | 2018 |
Unstructural biology of TRP ion channels: the role of intrinsically disordered regions in channel function and regulation B Goretzki, C Guhl, F Tebbe, JM Harder, UA Hellmich Journal of Molecular Biology 433 (17), 166931, 2021 | 31 | 2021 |
Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk JC Heiby, B Goretzki, CM Johnson, UA Hellmich, H Neuweiler Nature communications 10 (1), 4378, 2019 | 31 | 2019 |
Probing the molecular dynamics of the ABC multidrug transporter LmrA by deuterium solid-state nuclear magnetic resonance A Siarheyeva, JJ Lopez, I Lehner, UA Hellmich, HW van Veen, C Glaubitz Biochemistry 46 (11), 3075-3083, 2007 | 31 | 2007 |