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Dr Hui Hong
Dr Hui Hong
Department of Biochemistry, University of Cambridge
Подтвержден адрес электронной почты в домене cam.ac.uk
Название
Процитировано
Процитировано
Год
Prediction and manipulation of the stereochemistry of enoylreduction in modular polyketide synthases
DH Kwan, Y Sun, F Schulz, H Hong, B Popovic, JCC Sim-Stark, ...
Chemistry & biology 15 (11), 1231-1240, 2008
1602008
Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137
BM Harvey, T Mironenko, Y Sun, H Hong, Z Deng, PF Leadlay, ...
Chemistry & biology 14 (6), 703-714, 2007
1352007
Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria
H Hong, C Demangel, SJ Pidot, PF Leadlay, T Stinear
Natural product reports 25 (3), 447-454, 2008
1322008
Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation
L Guenin-Macé, R Veyron-Churlet, MI Thoulouze, G Romet-Lemonne, ...
The Journal of clinical investigation 123 (4), 1501-1512, 2013
1082013
Mycolactone Diffuses from Mycobacterium ulcerans–Infected Tissues and Targets Mononuclear Cells in Peripheral Blood and Lymphoid Organs
H Hong, E Coutanceau, M Leclerc, L Caleechurn, PF Leadlay, ...
PLoS neglected tropical diseases 2 (10), e325, 2008
1032008
Common Evolutionary Origin for the Unstable Virulence Plasmid pMUM Found in Geographically Diverse Strains of Mycobacterium ulcerans
TP Stinear, H Hong, W Frigui, MJ Pryor, R Brosch, T Garnier, PF Leadlay, ...
Journal of bacteriology 187 (5), 1668-1676, 2005
1002005
Analysis of the tetronomycin gene cluster: insights into the biosynthesis of a polyether tetronate antibiotic
Y Demydchuk, Y Sun, H Hong, J Staunton, JB Spencer, PF Leadlay
ChemBioChem 9 (7), 1136-1145, 2008
912008
A late‐stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster
ME Yurkovich, PA Tyrakis, H Hong, Y Sun, M Samborskyy, K Kamiya, ...
ChemBioChem 13 (1), 66-71, 2012
802012
Identification of a Phosphopantetheinyl Transferase for Erythromycin Biosynthesis in Saccharopolyspora erythraea
KJ Weissman, H Hong, M Oliynyk, AP Siskos, PF Leadlay
ChemBioChem 5 (1), 116-125, 2004
782004
Analysis of specific mutants in the lasalocid gene cluster: evidence for enzymatic catalysis of a disfavoured polyether ring closure
L Smith, H Hong, JB Spencer, PF Leadlay
ChemBioChem 9 (18), 2967-2975, 2008
752008
Glyceryl‐S‐Acyl Carrier Protein as an Intermediate in the Biosynthesis of Tetronate Antibiotics
Y Sun, H Hong, F Gillies, JB Spencer, PF Leadlay
ChemBioChem 9 (1), 150-156, 2008
742008
Fragmentation studies on monensin A and B by accurate‐mass electrospray tandem mass spectrometry
NP Lopes, CBW Stark, H Hong, PJ Gates, J Staunton
Rapid communications in mass spectrometry 16 (5), 414-420, 2002
732002
Evidence that a novel thioesterase is responsible for polyketide chain release during biosynthesis of the polyether ionophore monensin
BM Harvey, H Hong, MA Jones, ZA Hughes‐Thomas, RM Goss, ...
ChemBioChem 7 (9), 1435-1442, 2006
722006
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones
SJ Pidot, H Hong, T Seemann, JL Porter, MJ Yip, A Men, M Johnson, ...
BMC genomics 9, 1-15, 2008
712008
The fragmentation mechanism of five-membered lactones by electrospray ionisation tandem mass spectrometry
AEM Crotti, T Fonseca, H Hong, J Staunton, SE Galembeck, NP Lopes, ...
International Journal of Mass Spectrometry 232 (3), 271-276, 2004
692004
A common origin for guanidinobutanoate starter units in antifungal natural products.
H Hong, T Fill, PF Leadlay
Angewandte Chemie 125 (49), 2013
662013
Rapamycin biosynthesis: elucidation of gene product function
MA Gregory, H Hong, RE Lill, S Gaisser, H Petkovic, L Low, LS Sheehan, ...
Organic & biomolecular chemistry 4 (19), 3565-3568, 2006
652006
Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus
MA Gregory, S Gaisser, RE Lill, H Hong, RM Sheridan, B Wilkinson, ...
Angewandte Chemie (International ed. in English) 43 (19), 2551-2553, 2004
602004
A Novel Mycolactone from a Clinical Isolate of Mycobacterium ulcerans Provides Evidence for Additional Toxin Heterogeneity as a Result of Specific Changes in …
H Hong, JB Spencer, JL Porter, PF Leadlay, T Stinear
Chembiochem 6 (4), 643-648, 2005
562005
Unusual acetylation–elimination in the formation of tetronate antibiotics
C Kanchanabanca, W Tao, H Hong, Y Liu, F Hahn, M Samborskyy, ...
Angewandte Chemie 125 (22), 5897-5900, 2013
552013
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Статьи 1–20