Jörg Menche

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Albert-László BarabásiNortheastern University, Harvard Medical SchoolVerified email at neu.edu
Amitabh SharmaAssistant Professor of Medicine, Harvard Medical SchoolVerified email at channing.harvard.edu
Susan Dina GhiassianScipher MedicineVerified email at sciphermedicine.com
Marc VidalProfessor of Genetics, Harvard Medical SchoolVerified email at dfci.harvard.edu
Emre GuneyCTO, Head of Discovery and Data Science at STALICLAVerified email at stalicla.com
Maksim KitsakAssistant Professor, Faculty of Electrical Engineering, Mathematics and Computer Science, TU DelftVerified email at tudelft.nl
Michael CalderaMax Perutz LabsVerified email at univie.ac.at
Joseph LoscalzoProfessor of Medicine, Harvard Medical SchoolVerified email at partners.org
Loan VulliardMax Perutz LabsVerified email at cemm.oeaw.ac.at
Stefan KubicekCeMM Research Center for Molecular Medicine of the Austrian Academy of SciencesVerified email at cemm.oeaw.ac.at
Ed SilvermanVerified email at channing.harvard.edu
Xuezhong ZhouBeijing Jiaotong UniversityVerified email at bjtu.edu.cn
Christoph BockCeMM Research Center for Molecular Medicine & Medical University of Vienna, AustriaVerified email at bock.name
Joanna LoizouGroup Leader, Institute of Cancer Research, Medical University of ViennaVerified email at meduniwien.ac.at
Radu DobrinBristol-Myers Squibb CoVerified email at mssm.edu
Frederic BaribaudJanssen R&DVerified email at its.jnj.com
Natali GulbahceUniversity of California, San FranciscoVerified email at ucsf.edu
Harald H.H.W. SchmidtProfessor & Chair of Pharmacology and Personalised Medicine, University of MaastrichtVerified email at maastrichtuniversity.nl
Scott T. WeissProfessor of Medicine, Harvard Medical SchoolVerified email at channing.harvard.edu
Michel OwusuPhD student, CeMMVerified email at cemm.oeaw.ac.at

Jörg Menche

University of Vienna, Max Perutz Labs

Verified email at univie.ac.at - Homepage

Network Medicine Systems Biology Computational Biology Network Science Virtual Reality


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A proteome-scale map of the human interactome network T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ... Cell 159 (5), 1212-1226, 2014	1233	2014
Uncovering disease-disease relationships through the incomplete interactome J Menche, A Sharma, M Kitsak, SD Ghiassian, M Vidal, J Loscalzo, ... Science 347 (6224), 1257601, 2015	1106	2015
Human symptoms–disease network XZ Zhou, J Menche, AL Barabási, A Sharma Nature communications 5 (1), 1-10, 2014	557	2014
Canonical Genetic Signatures of the Adult Human Brain M Hawrylycz, JA Miller, V Menon, D Feng, T Dolbeare, ... Nature Neuroscience, 2015	405	2015
Network-based in silico drug efficacy screening E Guney, J Menche, M Vidal, AL Barábasi Nature communications 7 (1), 1-13, 2016	349	2016
A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome SD Ghiassian, J Menche, AL Barabási PLoS computational biology 11 (4), e1004120, 2015	294	2015
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma A Sharma, J Menche, CC Huang, T Ort, X Zhou, M Kitsak, N Sahni, ... Human molecular genetics 24 (11), 3005-3020, 2015	166	2015
Assessment of network module identification across complex diseases S Choobdar, ME Ahsen, J Crawford, M Tomasoni, T Fang, D Lamparter, ... Nature methods 16 (9), 843-852, 2019	165*	2019
Tissue specificity of human disease module M Kitsak, A Sharma, J Menche, E Guney, SD Ghiassian, J Loscalzo, ... Scientific reports 6 (1), 1-12, 2016	89	2016
Interactome-based approaches to human disease M Caldera, P Buphamalai, F Müller, J Menche Current Opinion in Systems Biology 3, 88-94, 2017	79	2017
Endophenotype network models: common core of complex diseases SD Ghiassian, J Menche, DI Chasman, F Giulianini, R Wang, P Ricchiuto, ... Scientific reports 6 (1), 1-13, 2016	68	2016
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers S Schick, AF Rendeiro, K Runggatscher, A Ringler, B Boidol, M Hinkel, ... Nature genetics 51 (9), 1399-1410, 2019	65	2019
Asymptotic properties of degree-correlated scale-free networks J Menche, A Valleriani, R Lipowsky Physical Review E 81 (4), 046103, 2010	57	2010
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation S Sdelci, AF Rendeiro, P Rathert, W You, JMG Lin, A Ringler, G Hofstätter, ... Nature genetics 51 (6), 990-998, 2019	48	2019
B cell–activating factor neutralization aggravates atherosclerosis D Tsiantoulas, AP Sage, L Göderle, M Ozsvar-Kozma, D Murphy, ... Circulation 138 (20), 2263-2273, 2018	47	2018
Type I interferon signaling disrupts the hepatic urea cycle and alters systemic metabolism to suppress T cell function A Lercher, A Bhattacharya, AM Popa, M Caldera, MF Schlapansky, ... Immunity 51 (6), 1074-1087. e9, 2019	46	2019
Mutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasms F Schischlik, R Jäger, F Rosebrock, E Hug, M Schuster, R Holly, E Fuchs, ... Blood, The Journal of the American Society of Hematology 134 (2), 199-210, 2019	46	2019
Integrating personalized gene expression profiles into predictive disease-associated gene pools J Menche, E Guney, A Sharma, PJ Branigan, MJ Loza, F Baribaud, ... NPJ systems biology and applications 3 (1), 1-10, 2017	46	2017
An inter‐species protein–protein interaction network across vast evolutionary distance Q Zhong, SJ Pevzner, T Hao, Y Wang, R Mosca, J Menche, M Taipale, ... Molecular systems biology 12 (4), 865, 2016	43	2016
Plasticity of the cullin-RING ligase repertoire shapes sensitivity to ligand-induced protein degradation C Mayor-Ruiz, MG Jaeger, S Bauer, M Brand, C Sin, A Hanzl, AC Mueller, ... Molecular cell 75 (4), 849-858. e8, 2019	41	2019

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