| The repertoire of mutational signatures in human cancer LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AWT Ng, Y Wu, A Boot, ... Nature 578 (7793), 94-101, 2020 | 2377 | 2020 |
| Pan-cancer analysis of whole genomes I The, TPCA of Whole, Genomes Consortium Nature 578 (7793), 82, 2020 | 1499 | 2020 |
| Integrated genomic and molecular characterization of cervical cancer TCGAR Network Nature 543, 378-384, 2017 | 1011* | 2017 |
| Patterns of somatic structural variation in human cancer genomes Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ... Nature 578 (7793), 112-121, 2020 | 689 | 2020 |
| Analyses of non-coding somatic drivers in 2,658 cancer whole genomes E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ... Nature 578 (7793), 102-111, 2020 | 499 | 2020 |
| An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers K Chan, SA Roberts, LJ Klimczak, JF Sterling, N Saini, EP Malc, J Kim, ... Nature genetics 47 (9), 1067, 2015 | 404 | 2015 |
| The repertoire of mutational signatures in human cancer L Alexandrov, J Kim, NJ Haradhvala, MN Huang, AWT Ng, A Boot, ... BioRxiv, 322859, 2018 | 174 | 2018 |
| Large multi-chromosomal duplications encompass many members of the olfactory receptor gene family in the human genome BJ Trask, H Massa, V Brand-Arpon, K Chan, C Friedman, OT Nguyen, ... Human molecular genetics 7 (13), 2007-2020, 1998 | 135 | 1998 |
| Clusters of multiple mutations: incidence and molecular mechanisms K Chan, DA Gordenin Annual review of genetics 49, 243-267, 2015 | 131 | 2015 |
| Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent K Chan, JF Sterling, SA Roberts, AS Bhagwat, MA Resnick, DA Gordenin PLoS genetics 8 (12), e1003149, 2012 | 104 | 2012 |
| Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure KC Akdemir, VT Le, JM Kim, S Killcoyne, DA King, YP Lin, Y Tian, A Inoue, ... Nature genetics 52 (11), 1178-1188, 2020 | 103 | 2020 |
| The impact of environmental and endogenous damage on somatic mutation load in human skin fibroblasts N Saini, SA Roberts, LJ Klimczak, K Chan, SA Grimm, S Dai, DC Fargo, ... PLoS genetics 12 (10), e1006385, 2016 | 101 | 2016 |
| The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis K Chan, MA Resnick, DA Gordenin DNA repair 12 (11), 878-889, 2013 | 95 | 2013 |
| Sex differences in oncogenic mutational processes CH Li, SD Prokopec, RX Sun, F Yousif, N Schmitz, PC Boutros Nature communications 11 (1), 1-24, 2020 | 65 | 2020 |
| Multiple specific binding targets for inhaled anesthetics in the mammalian brain MF Eckenhoff, K Chan, RG Eckenhoff Journal of Pharmacology and Experimental Therapeutics 300 (1), 172-179, 2002 | 45 | 2002 |
| Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples MH Bailey, WU Meyerson, LJ Dursi, LB Wang, G Dong, WW Liang, ... Nature communications 11 (1), 1-27, 2020 | 38 | 2020 |
| Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation CJ Sakofsky, N Saini, LJ Klimczak, K Chan, EP Malc, PA Mieczkowski, ... PLoS Biology 17 (9), e3000464, 2019 | 38 | 2019 |
| Germline determinants of the somatic mutation landscape in 2,642 cancer genomes SM Waszak, G Tiao, B Zhu, T Rausch, F Muyas, B Rodriguez-Martin, ... bioRxiv, 2017 | 34 | 2017 |
| Selective and mechanistic sources of recurrent rearrangements across the cancer genome JA Wala, O Shapira, Y Li, D Craft, SE Schumacher, M Imielinski, JE Haber, ... BioRxiv, 187609, 2017 | 29 | 2017 |
| Low-affinity analytical chromatography for measuring inhaled anesthetic binding to isolated proteins K Chan, QC Meng, JS Johansson, RG Eckenhoff Analytical biochemistry 301 (2), 308-313, 2002 | 13 | 2002 |
