| Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer I Garcia-Murillas, G Schiavon, B Weigelt, C Ng, S Hrebien, RJ Cutts, ... Science translational medicine 7 (302), 302ra133-302ra133, 2015 | 1186 | 2015 |
| Plasma ESR1 mutations and the treatment of estrogen receptor-positive advanced breast cancer. C Fribbens, B O'Leary, L Kilburn, S Hrebien, I Garcia-Murillas, M Beaney, ... | 695 | 2016 |
| Early adaptation and acquired resistance to CDK4/6 inhibition in estrogen receptor–positive breast cancer MT Herrera-Abreu, M Palafox, U Asghar, MA Rivas, RJ Cutts, ... Cancer research 76 (8), 2301-2313, 2016 | 640 | 2016 |
| Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer G Schiavon, S Hrebien, I Garcia-Murillas, RJ Cutts, A Pearson, ... Science translational medicine 7 (313), 313ra182-313ra182, 2015 | 573 | 2015 |
| The genetic landscape and clonal evolution of breast cancer resistance to palbociclib plus fulvestrant in the PALOMA-3 trial B O'Leary, RJ Cutts, Y Liu, S Hrebien, X Huang, K Fenwick, F André, ... Cancer discovery 8 (11), 1390-1403, 2018 | 464 | 2018 |
| Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer B O’Leary, S Hrebien, JP Morden, M Beaney, C Fribbens, X Huang, Y Liu, ... Nature communications 9 (1), 896, 2018 | 368 | 2018 |
| Forced mitotic entry of S-phase cells as a therapeutic strategy induced by inhibition of WEE1 M Aarts, R Sharpe, I Garcia-Murillas, H Gevensleben, MS Hurd, ... Cancer discovery 2 (6), 524-539, 2012 | 306 | 2012 |
| Assessment of molecular relapse detection in early-stage breast cancer I Garcia-Murillas, N Chopra, I Comino-Méndez, M Beaney, H Tovey, ... JAMA oncology 5 (10), 1473-1478, 2019 | 277 | 2019 |
| Diverse BRCA1 and BRCA2 Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer B Weigelt, I Comino-Méndez, I de Bruijn, L Tian, JL Meisel, ... Clinical Cancer Research 23 (21), 6708-6720, 2017 | 236 | 2017 |
| Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR H Gevensleben, I Garcia-Murillas, MK Graeser, G Schiavon, P Osin, ... Clinical Cancer Research 19 (12), 3276-3284, 2013 | 209 | 2013 |
| Serial next-generation sequencing of circulating cell-free DNA evaluating tumor clone response to molecularly targeted drug administration JS Frenel, S Carreira, J Goodall, D Roda, R Perez-Lopez, N Tunariu, ... Clinical Cancer Research 21 (20), 4586-4596, 2015 | 201 | 2015 |
| Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer C Fribbens, IG Murillas, M Beaney, S Hrebien, B O’Leary, L Kilburn, ... Annals of Oncology 29 (1), 145-153, 2018 | 161 | 2018 |
| Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance LA Martin, R Ribas, N Simigdala, E Schuster, S Pancholi, T Tenev, ... Nature communications 8 (1), 1865, 2017 | 136 | 2017 |
| Early ctDNA dynamics as a surrogate for progression-free survival in advanced breast cancer in the BEECH trial S Hrebien, V Citi, I Garcia-Murillas, R Cutts, K Fenwick, I Kozarewa, ... Annals of Oncology 30 (6), 945-952, 2019 | 122 | 2019 |
| Predicting response to radical (chemo) radiotherapy with circulating HPV DNA in locally advanced head and neck squamous carcinoma JY Lee, I Garcia-Murillas, RJ Cutts, DG De Castro, L Grove, T Hurley, ... British journal of cancer 117 (6), 876-883, 2017 | 110 | 2017 |
| ESR1 Mutations and Overall Survival on Fulvestrant versus Exemestane in Advanced Hormone Receptor–Positive Breast Cancer: A Combined Analysis of the … NC Turner, C Swift, L Kilburn, C Fribbens, M Beaney, I Garcia-Murillas, ... Clinical Cancer Research 26 (19), 5172-5177, 2020 | 105 | 2020 |
| The genetic landscape and clonal evolution of breast cancer resistance to palbociclib plus fulvestrant in the PALOMA-3 trial. Cancer Discov. 2018; 8: 1390–1403. doi: 10.1158 … B O’leary, RJ Cutts, Y Liu, S Hrebien, X Huang, K Fenwick, F André, ... A comprehensive manuscript describing various mechanisms of resistance to …, 0 | 101 | |
| Inactivating NF1 Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance A Pearson, P Proszek, J Pascual, C Fribbens, MK Shamsher, B Kingston, ... Clinical Cancer Research 26 (3), 608-622, 2020 | 97 | 2020 |
| lazaro encodes a lipid phosphate phosphohydrolase that regulates phosphatidylinositol turnover during Drosophila phototransduction I Garcia-Murillas, T Pettitt, E Macdonald, H Okkenhaug, P Georgiev, ... Neuron 49 (4), 533-546, 2006 | 77 | 2006 |
| Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels P Raghu, E Coessens, M Manifava, P Georgiev, T Pettitt, E Wood, ... Journal of cell biology 185 (1), 129-145, 2009 | 74 | 2009 |
