| PROTAC targeted protein degraders: the past is prologue M Békés, DR Langley, CM Crews Nature Reviews Drug Discovery 21 (3), 181-200, 2022 | 1099 | 2022 |
| Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ... Science advances 6 (42), eabd4596, 2020 | 329 | 2020 |
| Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs J Mikolajczyk, M Drag, M Békés, JT Cao, Z Ronai, GS Salvesen Journal of Biological Chemistry 282 (36), 26217-26224, 2007 | 194 | 2007 |
| Deubiquitinases as a signaling target of oxidative stress XM Cotto-Rios, M Bekes, J Chapman, B Ueberheide, TT Huang Cell reports 2 (6), 1475-1484, 2012 | 161 | 2012 |
| Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase JR Horton, K Liebert, M Bekes, A Jeltsch, X Cheng Journal of molecular biology 358 (2), 559-570, 2006 | 148 | 2006 |
| Recognition of Lys48-linked di-ubiquitin and deubiquitinating activities of the SARS coronavirus papain-like protease M Békés, R Ekkebus, H Ovaa, TT Huang, CD Lima Molecular cell 62 (4), 572-585, 2016 | 138 | 2016 |
| Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design W Rut, Z Lv, M Zmudzinski, S Patchett, D Nayak, SJ Snipas, F El Oualid, ... biorxiv, 2020.04. 29.068890, 2020 | 113 | 2020 |
| The dynamics and mechanism of SUMO chain deconjugation by SUMO-specific proteases M Békés, J Prudden, T Srikumar, B Raught, MN Boddy, GS Salvesen Journal of Biological Chemistry 286 (12), 10238-10247, 2011 | 93 | 2011 |
| Protection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1 S Zhu, J Goeres, KM Sixt, M Békés, XD Zhang, GS Salvesen, MJ Matunis Molecular cell 33 (5), 570-580, 2009 | 90 | 2009 |
| Development of small molecule inhibitors and probes of human SUMO deconjugating proteases VE Albrow, EL Ponder, D Fasci, M Békés, E Deu, GS Salvesen, M Bogyo Chemistry & biology 18 (6), 722-732, 2011 | 74 | 2011 |
| The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway KI Piatkov, L Colnaghi, M Békés, A Varshavsky, TT Huang Molecular cell 48 (6), 926-933, 2012 | 72 | 2012 |
| Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes) M Drag, J Mikolajczyk, M Bekes, FE Reyes-Turcu, JA Ellman, ... Biochemical Journal 415 (3), 367-375, 2008 | 72 | 2008 |
| SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme M Békés, W Rut, P Kasperkiewicz, MPC Mulder, H Ovaa, M Drag, ... Biochemical Journal 468 (2), 215-226, 2015 | 66 | 2015 |
| Synthetic substrates for measuring activity of autophagy proteases-autophagins (Atg4) Autophagins (Atg4) CW Shu, M Drag, M Bekes, D Zhai, GS Salvesen, JC Reed Autophagy 6 (7), 936-947, 2010 | 57 | 2010 |
| Functional characterization of a SUMO deconjugating protease of Plasmodium falciparum using newly identified small molecule inhibitors EL Ponder, VE Albrow, BA Leader, M Békés, J Mikolajczyk, UP Fonović, ... Chemistry & biology 18 (6), 711-721, 2011 | 55 | 2011 |
| Engineered hybrid dimers: tracking the activation pathway of caspase-7 JB Denault, M Békés, FL Scott, KMB Sexton, M Bogyo, GS Salvesen Molecular cell 23 (4), 523-533, 2006 | 50 | 2006 |
| SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function KE Coleman, M Bekes, JR Chapman, SB Crist, MJK Jones, ... Elife 6, e24325, 2017 | 44 | 2017 |
| DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells M Békés, K Okamoto, SB Crist, MJ Jones, JR Chapman, BB Brasher, ... Cell reports 5 (3), 826-838, 2013 | 42 | 2013 |
| A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease S Patchett, Z Lv, W Rut, M Békés, M Drag, SK Olsen, TT Huang Cell Reports 36 (13), 2021 | 35 | 2021 |
| Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes W Rut, M Zmudzinski, SJ Snipas, M Bekes, TT Huang, M Drag Chemical Science 11 (23), 6058-6069, 2020 | 26 | 2020 |
