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Bárbara B. Sousa
Bárbara B. Sousa
Подтвержден адрес электронной почты в домене medicina.ulisboa.pt
Название
Процитировано
Процитировано
Год
Allosteric antagonist modulation of TRPV2 by piperlongumine impairs glioblastoma progression
J Conde, RA Pumroy, C Baker, T Rodrigues, A Guerreiro, BB Sousa, ...
ACS Central Science 7 (5), 868-881, 2021
432021
Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents
A Istrate, MB Geeson, CD Navo, BB Sousa, MC Marques, RJ Taylor, ...
Journal of the American Chemical Society 144 (23), 10396-10406, 2022
312022
Structural insights into TRPV2 activation by small molecules
RA Pumroy, AD Protopopova, TC Fricke, IU Lange, FM Haug, PT Nguyen, ...
Nature communications 13 (1), 2334, 2022
272022
Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors
JD Seixas, BB Sousa, MC Marques, A Guerreiro, R Traquete, T Rodrigues, ...
RSC Chemical Biology 1 (4), 251-262, 2020
9*2020
TRPV2 interaction with small molecules and lipids revealed by cryo-EM
AD Protopopova, RA Pumroy, J de la Roche, FM Haug, BB Sousa, ...
BioRxiv, 2020.08. 10.242008, 2020
72020
Ibrutinib Inhibits BMX-Dependent Endothelial VCAM-1 Expression In Vitro and Pro-Atherosclerotic Endothelial Activation and Platelet Adhesion In Vivo
TCL Kohs, SR Olson, J Pang, KR Jordan, TJ Zheng, A Xie, J Hodovan, ...
Cellular and Molecular Bioengineering 15 (3), 231-243, 2022
62022
Unlocking the Potential of Bio‐Based Nitrogen‐Rich Furanic Platforms as Biomass Synthons
RFA Gomes, BMF Gonçalves, KHS Andrade, BB Sousa, N Maulide, ...
Angewandte Chemie 135 (28), e202304449, 2023
52023
Selective inhibition of Bruton’s tyrosine kinase by a designed covalent ligand leads to potent therapeutic efficacy in blood cancers relative to clinically used inhibitors
BB Sousa, CR de Almeida, AF Barahona, R Lopes, A Martins-Logrado, ...
ACS Pharmacology & Translational Science 5 (11), 1156-1168, 2022
32022
Merging the Isonitrile‐Tetrazine (4+ 1) Cycloaddition and the Ugi Four‐Component Reaction into a Single Multicomponent Process
Y Méndez, AV Vasco, G Ivey, AL Dias, P Gierth, BB Sousa, CD Navo, ...
Angewandte Chemie International Edition 62 (44), e202311186, 2023
12023
A scalable insect cell-based production process of the human recombinant BMX for in-vitro covalent ligand high-throughput screening
BB Sousa, MFQ Sousa, MC Marques, JD Seixas, JA Brito, PM Matias, ...
Bioprocess and biosystems engineering 44, 209-215, 2021
12021
Design and Evaluation of PROTACs Targeting Acyl Protein Thioesterase 1
LAR Carvalho, BB Sousa, D Zaidman, H Kiely‐Collins, GJL Bernardes
ChemBioChem 25 (4), e202300736, 2024
2024
TRPV2 Modulation by Small Molecules and Lipids
AD Protopopova, RA Pumroy, J de la Roche, FM Haug, BB Sousa, ...
Biophysical Journal 120 (3), 112a, 2021
2021
CRYSTAL STRUCTURE OF BONE MARROW TYROSINE KINASE FROM CHROMOSOME X WITH COVALENT LIGANDS
BBDACB SOUSA
2018
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Статьи 1–13