Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways M Simons, J Gloy, A Ganner, A Bullerkotte, M Bashkurov, C Krönig, ... Nature genetics 37 (5), 537-543, 2005 | 908 | 2005 |
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination EA Otto, B Schermer, T Obara, JF O'Toole, KS Hiller, AM Mueller, RG Ruf, ... Nature genetics 34 (4), 413-420, 2003 | 737 | 2003 |
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease SH Low, S Vasanth, CH Larson, S Mukherjee, N Sharma, MT Kinter, ... Developmental cell 10 (1), 57-69, 2006 | 430 | 2006 |
FGF-7 modulates ureteric bud growth and nephron number in the developing kidney J Qiao, R Uzzo, T Obara-Ishihara, L Degenstein, E Fuchs, D Herzlinger Development 126 (3), 547-554, 1999 | 282 | 1999 |
roundabout4 is essential for angiogenesis in vivo VM Bedell, SY Yeo, KW Park, J Chung, P Seth, V Shivalingappa, J Zhao, ... Proceedings of the National Academy of Sciences 102 (18), 6373-6378, 2005 | 262 | 2005 |
Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry S Kim, NA Zaghloul, E Bubenshchikova, EC Oh, S Rankin, N Katsanis, ... Nature cell biology 13 (4), 351-360, 2011 | 254 | 2011 |
Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions. M Nakafuku, T Obara, K Kaibuchi, I Miyajima, A Miyajima, H Itoh, ... Proceedings of the National Academy of Sciences 85 (5), 1374-1378, 1988 | 254 | 1988 |
A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish S Liu, W Lu, T Obara, S Kuida, J Lehoczky, K Dewar, IA Drummond, ... Oxford University Press for The Company of Biologists Limited 129 (24), 5839 …, 2002 | 222 | 2002 |
The Zebrafish fleer Gene Encodes an Essential Regulator of Cilia Tubulin Polyglutamylation N Pathak, T Obara, S Mangos, Y Liu, IA Drummond Molecular biology of the cell 18 (11), 4353-4364, 2007 | 216 | 2007 |
The surface ectoderm is essential for nephric duct formation in intermediate mesoderm T Obara-Ishihara, J Kuhlman, L Niswander, D Herzlinger Development 126 (6), 1103-1108, 1999 | 192 | 1999 |
Isolation and characterization of a gene encoding a G-protein alpha subunit from Schizosaccharomyces pombe: involvement in mating and sporulation pathways. T Obara, M Nakafuku, M Yamamoto, Y Kaziro Proceedings of the National Academy of Sciences 88 (13), 5877-5881, 1991 | 192 | 1991 |
Polycystin-2 immunolocalization and function in zebrafish T Obara, S Mangos, Y Liu, J Zhao, S Wiessner, AG Kramer-Zucker, ... Journal of the American Society of Nephrology 17 (10), 2706-2718, 2006 | 130 | 2006 |
AB‐type cyclin negatively regulates conjugation via interacting with cell cycle ‘start’genes in fission yeast. T Obara‐Ishihara, H Okayama The EMBO journal 13 (8), 1863-1872, 1994 | 120 | 1994 |
Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localization of polycystin-2 in vivo and in vitro AJ Streets, DJ Moon, ME Kane, T Obara, ACM Ong Human molecular genetics 15 (9), 1465-1473, 2006 | 106 | 2006 |
A polycystin‐2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes A Giamarchi, S Feng, L Rodat‐Despoix, Y Xu, E Bubenshchikova, ... The EMBO journal 29 (7), 1176-1191, 2010 | 96 | 2010 |
Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2 S Feng, GM Okenka, CX Bai, AJ Streets, LJ Newby, BT DeChant, ... Journal of Biological Chemistry 283 (42), 28471-28479, 2008 | 67 | 2008 |
Nephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros Y Fukuyo, T Nakamura, E Bubenshchikova, R Powell, T Tsuji, ... Molecular medicine reports 9 (2), 457-465, 2014 | 50 | 2014 |
Fish and frogs: models for vertebrate cilia signaling O Wessely, T Obara Frontiers in bioscience: a journal and virtual library 13, 1866, 2008 | 40 | 2008 |
A comparative analysis of glomerulus development in the pronephros of medaka and zebrafish K Ichimura, E Bubenshchikova, R Powell, Y Fukuyo, T Nakamura, U Tran, ... Public Library of Science 7 (9), e45286, 2012 | 36 | 2012 |
Medaka fish, Oryzias latipes, as a model for human obesity-related glomerulopathy K Ichimura, Y Kawashima, T Nakamura, R Powell, Y Hidoh, S Terai, ... Biochemical and biophysical research communications 431 (4), 712-717, 2013 | 32 | 2013 |