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Peter C Tyler
Peter C Tyler
Ferrier Research Institute, Victoria University of Wellington
Verified email at vuw.ac.nz
Title
Cited by
Cited by
Year
Iminosugars as glycosidase inhibitors
A Stütz
Wiley-VCH, 1999
7051999
Iminosugars: From synthesis to therapeutic applications
P Compain, OR Martin
John Wiley & Sons, 2007
6292007
One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase
RW Miles, PC Tyler, RH Furneaux, CK Bagdassarian, VL Schramm
Biochemistry 37 (24), 8615-8621, 1998
3351998
Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes
GA Kicska, L Long, H Hörig, C Fairchild, PC Tyler, RH Furneaux, ...
Proceedings of the National Academy of Sciences 98 (8), 4593-4598, 2001
2412001
Transition State Structure of Purine Nucleoside Phosphorylase and Principles of Atomic Motion in Enzymatic Catalysis,
A Fedorov, W Shi, G Kicska, E Fedorov, PC Tyler, RH Furneaux, ...
Biochemistry 40 (4), 853-860, 2001
2412001
Liposomal delivery of antigen to human dendritic cells
MJ Copland, MA Baird, T Rades, JL McKenzie, B Becker, F Reck, ...
Vaccine 21 (9-10), 883-890, 2003
2222003
The 2.0 Å structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor
W Shi, CM Li, PC Tyler, RH Furneaux, C Grubmeyer, VL Schramm, ...
Nature structural biology 6 (6), 588-593, 1999
2041999
Femtomolar transition state analogue inhibitors of 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli
V Singh, GB Evans, DH Lenz, JM Mason, K Clinch, S Mee, GF Painter, ...
Journal of Biological Chemistry 280 (18), 18265-18273, 2005
1842005
Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase
A Lewandowicz, PC Tyler, GB Evans, RH Furneaux, VL Schramm
Journal of Biological Chemistry 278 (34), 31465-31468, 2003
1772003
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function
W Shi, LM Ting, GA Kicska, A Lewandowicz, PC Tyler, GB Evans, ...
Journal of Biological Chemistry 279 (18), 18103-18106, 2004
1762004
The 2.0 Å Structure of Malarial Purine Phosphoribosyltransferase in Complex with a Transition-State Analogue Inhibitor,
W Shi, CM Li, PC Tyler, RH Furneaux, SM Cahill, ME Girvin, C Grubmeyer, ...
Biochemistry 38 (31), 9872-9880, 1999
1741999
Purine-less Death in Plasmodium falciparumInduced by Immucillin-H, a Transition State Analogue of Purine Nucleoside Phosphorylase
GA Kicska, PC Tyler, GB Evans, RH Furneaux, VL Schramm, K Kim
Journal of Biological Chemistry 277 (5), 3226-3231, 2002
1632002
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins
LM Ting, W Shi, A Lewandowicz, V Singh, A Mwakingwe, MR Birck, ...
Journal of Biological Chemistry 280 (10), 9547-9554, 2005
1492005
Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases
CM Li, PC Tyler, RH Furneaux, G Kicska, Y Xu, C Grubmeyer, ME Girvin, ...
nature structural biology 6 (6), 582-587, 1999
1341999
Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum
GA Kicska, PC Tyler, GB Evans, RH Furneaux, K Kim, VL Schramm
Journal of Biological Chemistry 277 (5), 3219-3225, 2002
1312002
Prostaglandin E2-bisphosphonate conjugates: potential agents for treatment of osteoporosis
L Gil, Y Han, EE Opas, GA Rodan, R Ruel, JG Seedor, PC Tyler, ...
Bioorganic & medicinal chemistry 7 (5), 901-919, 1999
1261999
Exploring structure− activity relationships of transition state analogues of human purine nucleoside phosphorylase
GB Evans, RH Furneaux, A Lewandowicz, VL Schramm, PC Tyler
Journal of medicinal chemistry 46 (15), 3412-3423, 2003
1242003
Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine:  Convergent Synthesis of the Aza-C-nucleoside Immucillins
GB Evans, RH Furneaux, TL Hutchison, HS Kezar, PE Morris, ...
The Journal of organic chemistry 66 (17), 5723-5730, 2001
1232001
Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase
GB Evans, RH Furneaux, A Lewandowicz, VL Schramm, PC Tyler
Journal of medicinal chemistry 46 (24), 5271-5276, 2003
1222003
Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells
KL White, T Rades, RH Furneaux, PC Tyler, S Hook
Journal of pharmacy and pharmacology 58 (6), 729-737, 2006
1082006
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