Axicabtagene ciloleucel CAR T-cell therapy in refractory large B-cell lymphoma SS Neelapu, FL Locke, NL Bartlett, LJ Lekakis, DB Miklos, CA Jacobson, ... New England Journal of Medicine 377 (26), 2531-2544, 2017 | 4834 | 2017 |
ASTCT consensus grading for cytokine release syndrome and neurologic toxicity associated with immune effector cells DW Lee, BD Santomasso, FL Locke, A Ghobadi, CJ Turtle, JN Brudno, ... Biology of blood and marrow transplantation 25 (4), 625-638, 2019 | 2209 | 2019 |
Chimeric antigen receptor T-cell therapy—assessment and management of toxicities SS Neelapu, S Tummala, P Kebriaei, W Wierda, C Gutierrez, FL Locke, ... Nature reviews Clinical oncology 15 (1), 47-62, 2018 | 2078 | 2018 |
Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial FL Locke, A Ghobadi, CA Jacobson, DB Miklos, LJ Lekakis, OO Oluwole, ... The lancet oncology 20 (1), 31-42, 2019 | 1892 | 2019 |
KTE-X19 CAR T-cell therapy in relapsed or refractory mantle-cell lymphoma M Wang, J Munoz, A Goy, FL Locke, CA Jacobson, BT Hill, ... New England journal of medicine 382 (14), 1331-1342, 2020 | 1386 | 2020 |
Axicabtagene ciloleucel as second-line therapy for large B-cell lymphoma FL Locke, DB Miklos, CA Jacobson, MA Perales, MJ Kersten, OO Oluwole, ... New England Journal of Medicine 386 (7), 640-654, 2022 | 819 | 2022 |
Phase 1 results of ZUMA-1: a multicenter study of KTE-C19 anti-CD19 CAR T cell therapy in refractory aggressive lymphoma FL Locke, SS Neelapu, NL Bartlett, T Siddiqi, JC Chavez, CM Hosing, ... Molecular Therapy 25 (1), 285-295, 2017 | 665 | 2017 |
Standard-of-care axicabtagene ciloleucel for relapsed or refractory large B-cell lymphoma: results from the US Lymphoma CAR T Consortium LJ Nastoupil, MD Jain, L Feng, JY Spiegel, A Ghobadi, Y Lin, S Dahiya, ... Journal of Clinical Oncology 38 (27), 3119, 2020 | 594 | 2020 |
Management of immunotherapy-related toxicities, version 1.2019, NCCN clinical practice guidelines in oncology JA Thompson, BJ Schneider, J Brahmer, S Andrews, P Armand, S Bhatia, ... Journal of the National Comprehensive Cancer Network 17 (3), 255-289, 2019 | 492 | 2019 |
Real-world evidence of tisagenlecleucel for pediatric acute lymphoblastic leukemia and non-Hodgkin lymphoma MC Pasquini, ZH Hu, K Curran, T Laetsch, F Locke, R Rouce, ... Blood advances 4 (21), 5414-5424, 2020 | 331 | 2020 |
Tumor burden, inflammation, and product attributes determine outcomes of axicabtagene ciloleucel in large B-cell lymphoma FL Locke, JM Rossi, SS Neelapu, CA Jacobson, DB Miklos, A Ghobadi, ... Blood advances 4 (19), 4898-4911, 2020 | 279 | 2020 |
Cardiovascular events among adults treated with chimeric antigen receptor T-cells (CAR-T) RM Alvi, MJ Frigault, MG Fradley, MD Jain, SS Mahmood, M Awadalla, ... Journal of the American College of Cardiology 74 (25), 3099-3108, 2019 | 269 | 2019 |
CAR-HEMATOTOX: a model for CAR T-cell–related hematologic toxicity in relapsed/refractory large B-cell lymphoma K Rejeski, A Perez, P Sesques, E Hoster, C Berger, L Jentzsch, ... Blood, The Journal of the American Society of Hematology 138 (24), 2499-2513, 2021 | 230 | 2021 |
Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit'ALL' SS Neelapu, S Tummala, P Kebriaei, W Wierda, FL Locke, Y Lin, N Jain, ... Nature reviews Clinical oncology 15 (4), 218-218, 2018 | 209 | 2018 |
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events MV Maus, S Alexander, MR Bishop, JN Brudno, C Callahan, ML Davila, ... Journal for immunotherapy of cancer 8 (2), 2020 | 189 | 2020 |
Immune reconstitution and associated infections following axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma JM Logue, E Zucchetti, CA Bachmeier, GS Krivenko, V Larson, D Ninh, ... Haematologica 106 (4), 978, 2021 | 182 | 2021 |
Tumor interferon signaling and suppressive myeloid cells are associated with CAR T-cell failure in large B-cell lymphoma MD Jain, H Zhao, X Wang, R Atkins, M Menges, K Reid, K Spitler, ... Blood, The Journal of the American Society of Hematology 137 (19), 2621-2633, 2021 | 166 | 2021 |
High metabolic tumor volume is associated with decreased efficacy of axicabtagene ciloleucel in large B-cell lymphoma EA Dean, RS Mhaskar, H Lu, MS Mousa, GS Krivenko, A Lazaryan, ... Blood Advances 4 (14), 3268-3276, 2020 | 163 | 2020 |
Preliminary results of prophylactic tocilizumab after axicabtageneciloleucel (axi-cel; KTE-C19) treatment for patients with refractory, aggressive non-Hodgkin lymphoma (NHL) FL Locke, SS Neelapu, NL Bartlett, LJ Lekakis, CA Jacobson, ... Blood 130, 1547, 2017 | 158 | 2017 |
Efficacy and safety of CD19‐directed CAR‐T cell therapies in patients with relapsed/refractory aggressive B‐cell lymphomas: Observations from the JULIET, ZUMA‐1, and TRANSCEND … JR Westin, MJ Kersten, G Salles, JS Abramson, SJ Schuster, FL Locke, ... American journal of hematology 96 (10), 1295-1312, 2021 | 138 | 2021 |