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Jaume Bonet
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Multivalent antibodies: when design surpasses evolution
ÁM Cuesta, N Sainz-Pastor, J Bonet, B Oliva, L Álvarez-Vallina
Trends in biotechnology 28 (7), 355-362, 2010
2472010
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
2242020
Inferring causal molecular networks: empirical assessment through a community-based effort
SM Hill, LM Heiser, T Cokelaer, M Unger, NK Nesser, DE Carlin, Y Zhang, ...
Nature methods 13 (4), 310-318, 2016
2112016
ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
RHG Wright, A Lioutas, F Le Dily, D Soronellas, A Pohl, J Bonet, AS Nacht, ...
Science 352 (6290), 1221-1225, 2016
1272016
CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells
RHG Wright, G Castellano, J Bonet, F Le Dily, J Font-Mateu, C Ballaré, ...
Genes & development 26 (17), 1972-1983, 2012
1172012
De novo protein design enables the precise induction of RSV-neutralizing antibodies
F Sesterhenn, C Yang, J Bonet, JT Cramer, X Wen, Y Wang, CI Chiang, ...
Science 368 (6492), eaay5051, 2020
972020
Rationale and design of a study assessing treatment strategies of atrial fibrillation in patients with heart failure: the Atrial Fibrillation and Congestive Heart Failure (AF …
E Agner, L Aguinaga, HB Andersen, JMO Arnold, L Reisin, ...
American Heart Journal 144 (4), 597-607, 2002
892002
Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis
SK Sieberts, F Zhu, J García-García, E Stahl, A Pratap, G Pandey, ...
Nature communications 7 (1), 1-10, 2016
882016
Characterization of protein hubs by inferring interacting motifs from protein interactions
R Aragues, A Sali, J Bonet, MA Marti-Renom, B Oliva
PLoS computational biology 3 (9), e178, 2007
742007
In Vivo Tumor Targeting and Imaging with Engineered Trivalent Antibody Fragments Containing Collagen-Derived Sequences
AM Cuesta, D Sánchez-Martín, L Sanz, J Bonet, M Compte, L Kremer, ...
PLoS One 4 (4), e5381, 2009
712009
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy
G Giordano-Attianese, P Gainza, E Gray-Gaillard, E Cribioli, S Shui, S Kim, ...
Nature Biotechnology 38 (4), 426-432, 2020
622020
Early risks of death, stroke/systemic embolism, and major bleeding in patients with newly diagnosed atrial fibrillation: results from the GARFIELD-AF registry
JP Bassand, S Virdone, SZ Goldhaber, AJ Camm, DA Fitzmaurice, ...
Circulation 139 (6), 787-798, 2019
552019
ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy
SL Harwood, A Alvarez-Cienfuegos, N Nunez-Prado, M Compte, ...
Oncoimmunology 7 (1), e1377874, 2018
532018
Amyloid-β peptide nitrotyrosination stabilizes oligomers and enhances NMDAR-mediated toxicity
B Guivernau, J Bonet, V Valls-Comamala, M Bosch-Morató, JA Godoy, ...
Journal of Neuroscience 36 (46), 11693-11703, 2016
532016
Understanding protein–protein interactions using local structural features
J Planas-Iglesias, J Bonet, J García-García, MA Marín-López, E Feliu, ...
Journal of molecular biology 425 (7), 1210-1224, 2013
472013
Bottom-up de novo design of functional proteins with complex structural features
C Yang, F Sesterhenn, J Bonet, EA van Aalen, L Scheller, LA Abriata, ...
Nature Chemical Biology 17 (4), 492-500, 2021
452021
iLoops: a protein–protein interaction prediction server based on structural features
J Planas-Iglesias, MA Marin-Lopez, J Bonet, J Garcia-Garcia, B Oliva
Bioinformatics 29 (18), 2360-2362, 2013
452013
ArchDB 2014: structural classification of loops in proteins
J Bonet, J Planas-Iglesias, J Garcia-Garcia, MA Marín-López, ...
Nucleic acids research 42 (D1), D315-D319, 2014
372014
Management and 1‐year outcomes of patients with newly diagnosed atrial fibrillation and chronic kidney disease: results from the prospective GARFIELD‐AF registry
S Goto, P Angchaisuksiri, JP Bassand, AJ Camm, H Dominguez, ...
Journal of the American Heart Association 8 (3), e010510, 2019
362019
Rosetta FunFolDes–A general framework for the computational design of functional proteins
J Bonet, S Wehrle, K Schriever, C Yang, A Billet, F Sesterhenn, A Scheck, ...
PLoS computational biology 14 (11), e1006623, 2018
292018
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