Functional immobilization of signaling proteins enables control of stem cell fate K Alberti, RE Davey, K Onishi, S George, K Salchert, FP Seib, ... Nature methods 5 (7), 645-650, 2008 | 251 | 2008 |
LIF signaling in stem cells and development K Onishi, PW Zandstra Development 142 (13), 2230-2236, 2015 | 135 | 2015 |
LIF‐mediated control of embryonic stem cell self‐renewal emerges due to an autoregulatory loop RE Davey, K Onishi, A Mahdavi, PW Zandstra The FASEB Journal 21 (9), 2020-2032, 2007 | 97 | 2007 |
Oct4 is required∼ E7. 5 for proliferation in the primitive streak B DeVeale, I Brokhman, P Mohseni, T Babak, C Yoon, A Lin, K Onishi, ... PLoS genetics 9 (11), e1003957, 2013 | 92 | 2013 |
Manipulation of signaling thresholds in “engineered stem cell niches” identifies design criteria for pluripotent stem cell screens R Peerani, K Onishi, A Mahdavi, E Kumacheva, PW Zandstra PloS one 4 (7), e6438, 2009 | 92 | 2009 |
Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells F Moledina, G Clarke, A Oskooei, K Onishi, A Günther, PW Zandstra Proceedings of the National Academy of Sciences 109 (9), 3264-3269, 2012 | 78 | 2012 |
Modeling signaling‐dependent pluripotency with Boolean logic to predict cell fate transitions A Yachie‐Kinoshita, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, ... Molecular systems biology 14 (1), e7952, 2018 | 64 | 2018 |
Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency K Onishi, PD Tonge, A Nagy, PW Zandstra Stem cell reports 3 (1), 156-168, 2014 | 27 | 2014 |
Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK–STAT signaling K Onishi, PD Tonge, A Nagy, PW Zandstra Integrative Biology 4 (11), 1367-1376, 2012 | 21 | 2012 |
Synthetic peptide arrays for pathway-level protein monitoring by liquid chromatography-tandem mass spectrometry JA Hewel, J Liu, K Onishi, V Fong, S Chandran, JB Olsen, O Pogoutse, ... Molecular & Cellular Proteomics 9 (11), 2460-2473, 2010 | 21 | 2010 |
Modeling signaling-dependent pluripotent cell states with boolean logic can predict cell fate transitions A Yachie-Kinoshita, K Onishi, J Ostblom, E Posfai, J Rossant, ... bioRxiv, 115683, 2017 | 4 | 2017 |
Patterning of sharp cellular interfaces with a reconfigurable elastic substrate A Curtis, DJ Li, B DeVeale, K Onishi, MY Kim, R Blelloch, DJ Laird, EE Hui Integrative Biology 9 (1), 50-57, 2017 | 4 | 2017 |
COMPOSITIONS AND METHODS FOR TREATING SPINAL CORD INJURIES G Hogge, R Skaliter, J Bahr-davidson, F Binette, K Onishi, NC Manley, ... US Patent App. 18/833,784, 2024 | | 2024 |
Compositions and methods for treating spinal cord injuries F Binette, J Bahr-Davidson, R Skaliter, K Onishi, NC Manley, ... US Patent App. 18/262,909, 2024 | | 2024 |
Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells K Onishi, NC Manley, CR Halberstadt, EM Whiteley US Patent App. 18/074,272, 2023 | | 2023 |
Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells K Onishi, NC Manley, CR Halberstadt, EM Whiteley US Patent 11,603,518, 2023 | | 2023 |
Dissecting the Role of the Stem Cell Niche in Driving Conversion Between Pluripotent States K Onishi University of Toronto (Canada), 2014 | | 2014 |