| The systems biology graphical notation N Le Novere, M Hucka, H Mi, S Moodie, F Schreiber, A Sorokin, E Demir, ... Nature biotechnology 27 (8), 735-741, 2009 | 1048 | 2009 |
| The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response M Blanc, WY Hsieh, KA Robertson, KA Kropp, T Forster, G Shui, P Lacaze, ... Immunity 38 (1), 106-118, 2013 | 390 | 2013 |
| Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis M Blanc, WY Hsieh, KA Robertson, S Watterson, G Shui, P Lacaze, ... PLoS-Biology 9 (3), 455, 2011 | 296 | 2011 |
| Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies J McLaughlin, S Watterson, AM Layton, AJ Bjourson, E Barnard, ... Microorganisms 7 (5), 128, 2019 | 209 | 2019 |
| The genetics and screening of familial hypercholesterolaemia R Henderson, M O’Kane, V McGilligan, S Watterson Journal of Biomedical Science 23 (1), 39, 2016 | 176 | 2016 |
| Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms A Mazein, M Ostaszewski, I Kuperstein, S Watterson, N Le Novère, ... NPJ systems biology and applications 4 (1), 21, 2018 | 92 | 2018 |
| A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway A Mazein, S Watterson, WY Hsieh, WJ Griffiths, P Ghazal Biochemical Pharmacology 86 (1), 56-66, 2013 | 91 | 2013 |
| Digital clocks: simple Boolean models can quantitatively describe circadian systems OE Akman, S Watterson, A Parton, N Binns, AJ Millar, P Ghazal Journal of The Royal Society Interface 9 (74), 2365-2382, 2012 | 81 | 2012 |
| Logic models of pathway biology S Watterson, S Marshall, P Ghazal Drug discovery today 13 (9-10), 447-456, 2008 | 78 | 2008 |
| Computational modelling of atherosclerosis A Parton, V McGilligan, M O’Kane, FR Baldrick, S Watterson Briefings in Bioinformatics 17 (4), 562-575, 2016 | 67 | 2016 |
| Construction of a large scale integrated map of macrophage pathogen recognition and effector systems S Raza, N McDerment, PA Lacaze, K Robertson, S Watterson, Y Chen, ... BMC systems biology 4, 1-18, 2010 | 50 | 2010 |
| An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway KA Robertson, WY Hsieh, T Forster, M Blanc, H Lu, PJ Crick, E Yutuc, ... PLoS Biol 14 (3), e1002364, 2016 | 44 | 2016 |
| The interdependency and co-regulation of the vitamin D and cholesterol metabolism T Warren, R McAllister, A Morgan, TS Rai, V McGilligan, M Ennis, C Page, ... Cells 10 (8), 2007, 2021 | 39 | 2021 |
| Deep Learning in Systems Medicine E Pujos-Guillot, B Comte, JL de Miranda, V Spiwok, I Chorbev, ... Briefings in Bioinformatics 22 (2), 1543-1559, 2021 | 38* | 2021 |
| A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction S Watterson, ML Guerriero, M Blanc, A Mazein, L Loewe, KA Robertson, ... Biochimie 95 (3), 613-621, 2013 | 38 | 2013 |
| Role of tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and associated proteins in coronary artery disease and cardiac events M Chemaly, V McGilligan, M Gibson, M Clauss, S Watterson, ... Archives of cardiovascular diseases 110 (12), 700-711, 2017 | 35 | 2017 |
| Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis H Lu, S Talbot, KA Robertson, S Watterson, T Forster, D Roy, P Ghazal Steroids 99, 219-229, 2015 | 33 | 2015 |
| Network and systems medicine: Position paper of the european collaboration on science and technology action on open multiscale systems medicine B Comte, J Baumbach, A Benis, J Basílio, N Debeljak, Å Flobak, ... Network and systems medicine 3 (1), 67-90, 2020 | 24 | 2020 |
| New models of atherosclerosis and multi-drug therapeutic interventions. A Parton, V McGilligan, M Chemaly, M O’Kane, S Watterson Bioinformatics 35 (14), 2449-2457, 2018 | 24 | 2018 |
| Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway HE Benson, S Watterson, JL Sharman, CP Mpamhanga, A Parton, ... British journal of pharmacology 174 (23), 4362-4382, 2017 | 19 | 2017 |
Peter GhazalCardiff University, School of MedicineVerified email at cardiff.ac.uk
