| The Biginelli reaction with an imidazolium–tagged recyclable iron catalyst: Kinetics, mechanism, and antitumoral activity LM Ramos, BC Guido, CC Nobrega, JR Correa, RG Silva, ... Chemistry–A European Journal 19 (13), 4156-4168, 2013 | 145 | 2013 |
| Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme RG Silva, AS Murkin, VL Schramm Proceedings of the National Academy of Sciences 108 (46), 18661-18665, 2011 | 130 | 2011 |
| Selective mitochondrial staining with small fluorescent probes: Importance, design, synthesis, challenges and trends for new markers BAD Neto, JR Corrêa, RG Silva RSC Advances 3 (16), 5291-5301, 2013 | 93 | 2013 |
| Mass-dependent bond vibrational dynamics influence catalysis by HIV-1 protease DR Kipp, RG Silva, VL Schramm Journal of the American Chemical Society 133 (48), 19358-19361, 2011 | 76 | 2011 |
| Structures of human purine nucleoside phosphorylase complexed with inosine and ddI F Canduri, DM dos Santos, RG Silva, MA Mendes, LA Basso, MS Palma, ... Biochemical and biophysical research communications 313 (4), 907-914, 2004 | 75 | 2004 |
| Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation LA McAllister, CR Butler, S Mente, SV O’Neil, KR Fonseca, JR Piro, ... Journal of medicinal chemistry 61 (7), 3008-3026, 2018 | 73 | 2018 |
| Synthesis, properties and highly selective mitochondria staining with novel, stable and superior benzothiadiazole fluorescent probes BAD Neto, PHPR Carvalho, DCBD Santos, CC Gatto, LM Ramos, ... RSC Advances 2 (4), 1524-1532, 2012 | 71 | 2012 |
| Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir DM dos Santos, F Canduri, JH Pereira, MVB Dias, RG Silva, MA Mendes, ... Biochemical and biophysical research communications 308 (3), 553-559, 2003 | 67 | 2003 |
| Crystal structure of human purine nucleoside phosphorylase at 2.3 Å resolution WF de Azevedo, F Canduri, DM dos Santos, RG Silva, JS de Oliveira, ... Biochemical and biophysical research communications 308 (3), 545-552, 2003 | 61 | 2003 |
| Cloning, overexpression, and purification of functional human purine nucleoside phosphorylase RG Silva, LPS Carvalho, JS Oliveira, CA Pinto, MA Mendes, MS Palma, ... Protein expression and purification 27 (1), 158-164, 2003 | 53 | 2003 |
| An exceptionally potent inhibitor of human CD73 CE Bowman, RG da Silva, A Pham, SW Young Biochemistry 58 (31), 3331-3334, 2019 | 52 | 2019 |
| Structure of human PNP complexed with ligands F Canduri, RG Silva, DM dos Santos, MS Palma, LA Basso, DS Santos, ... Acta Crystallographica Section D: Biological Crystallography 61 (7), 856-862, 2005 | 52 | 2005 |
| Structural basis for inhibition of human PNP by immucillin-H WF de Azevedo, F Canduri, DM dos Santos, JH Pereira, MVB Dias, ... Biochemical and biophysical research communications 309 (4), 917-922, 2003 | 51 | 2003 |
| Docking and small angle X-ray scattering studies of purine nucleoside phosphorylase WF de Azevedo, GC dos Santos, DM dos Santos, JR Olivieri, F Canduri, ... Biochemical and biophysical research communications 309 (4), 923-928, 2003 | 50 | 2003 |
| Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine RG Silva, JH Pereira, F Canduri, WF de Azevedo, LA Basso, DS Santos Archives of biochemistry and biophysics 442 (1), 49-58, 2005 | 43 | 2005 |
| Crystal structure of human PNP complexed with guanine WF de Azevedo, F Canduri, DM dos Santos, JH Pereira, MVB Dias, ... Biochemical and biophysical research communications 312 (3), 767-772, 2003 | 43 | 2003 |
| Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: Purification and characterization IO Fonseca, MLB Magalhaes, JS Oliveira, RG Silva, MA Mendes, ... Protein expression and purification 46 (2), 429-437, 2006 | 36 | 2006 |
| Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein (ACP) reductase: Kinetic and chemical mechanisms RG Silva, LPS de Carvalho, JS Blanchard, DS Santos, LA Basso Biochemistry 45 (43), 13064-13073, 2006 | 29 | 2006 |
| Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell-and apicomplexan parasite-mediated diseases RG Silva, JE S Nunes, F Canduri, JC Borges, LM Gava, FB Moreno, ... Current drug targets 8 (3), 413-422, 2007 | 26 | 2007 |
| Mycobacterium tuberculosis β-ketoacyl-ACP reductase: α-Secondary kinetic isotope effects and kinetic and equilibrium mechanisms of substrate binding RG Silva, LA Rosado, DS Santos, LA Basso Archives of biochemistry and biophysics 471 (1), 1-10, 2008 | 25 | 2008 |
