| Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism F Chen, WAM Elgaher, M Winterhoff, K Büssow, FH Waqas, E Graner, ... Nature Metabolism 4 (5), 534-546, 2022 | 58 | 2022 |
| Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities AM Hayallah, WA Elgaher, OI Salem, AAM Abdel Alim Archives of pharmacal research 34, 3-21, 2011 | 48 | 2011 |
| Expanding the scaffold for bacterial RNA polymerase inhibitors: design, synthesis and structure–activity relationships of ureido-heterocyclic-carboxylic acids WAM Elgaher, M Fruth, M Groh, J Haupenthal, RW Hartmann Rsc Advances 4 (5), 2177-2194, 2014 | 44 | 2014 |
| Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis N Lababidi, EO Kissi, WAM Elgaher, V Sigal, J Haupenthal, BC Schwarz, ... Journal of controlled release 314, 62-71, 2019 | 41 | 2019 |
| Discovery and structure-based optimization of 2-Ureidothiophene-3-carboxylic acids as dual bacterial RNA polymerase and viral reverse transcriptase inhibitors WAM Elgaher, KK Sharma, J Haupenthal, F Saladini, M Pires, E Real, ... Journal of Medicinal Chemistry 59 (15), 7212-7222, 2016 | 34 | 2016 |
| Synthetic studies of cystobactamids as antibiotics and bacterial imaging carriers lead to compounds with high in vivo efficacy G Testolin, K Cirnski, K Rox, H Prochnow, V Fetz, C Grandclaudon, ... Chemical Science 11 (5), 1316-1334, 2020 | 29 | 2020 |
| Hit-optimization using target-directed dynamic combinatorial chemistry: development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase RP Jumde, M Guardigni, RM Gierse, A Alhayek, D Zhu, Z Hamid, ... Chemical Science 12 (22), 7775-7785, 2021 | 27 | 2021 |
| In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics F Graef, R Richter, V Fetz, X Murgia, C De Rossi, N Schneider-Daum, ... ACS infectious diseases 4 (8), 1188-1196, 2018 | 27 | 2018 |
| Discovery of Small-Molecule Stabilizers of 14-3-3 Protein–Protein Interactions via Dynamic Combinatorial Chemistry AM Hartman, WAM Elgaher, N Hertrich, SA Andrei, C Ottmann, ... ACS Medicinal Chemistry Letters 11 (5), 1041-1046, 2020 | 26 | 2020 |
| Protein‐Templated Hit Identification through an Ugi Four‐Component Reaction F Mancini, MY Unver, WAM Elgaher, VR Jumde, A Alhayek, P Lukat, ... Chemistry–A European Journal 26 (64), 14585-14593, 2020 | 22 | 2020 |
| Synthesis and biological evaluation of cystobactamid 507: a bacterial topoisomerase inhibitor from Cystobacter sp. M Moreno, WAM Elgaher, J Herrmann, N Schlaeger, MM Hamed, ... Synlett, 1175-1178, 2015 | 22 | 2015 |
| Cystobactamid 507: concise synthesis, mode of action, and optimization toward more potent antibiotics WAM Elgaher, MM Hamed, S Baumann, J Herrmann, L Siebenbürger, ... Chemistry–A European Journal 26 (32), 7219-7225, 2020 | 21 | 2020 |
| A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria R Richter, MAM Kamal, MA García-Rivera, J Kaspar, M Junk, ... Materials Today Bio 8, 100084, 2020 | 17 | 2020 |
| Semisynthesis and biological evaluation of amidochelocardin derivatives as broad-spectrum antibiotics C Grandclaudon, NVS Birudukota, WAM Elgaher, RP Jumde, S Yahiaoui, ... European journal of medicinal chemistry 188, 112005, 2020 | 15 | 2020 |
| Synthesis, anti-bronchoconstrictive, and antibacterial activities of some new 8-substituted-1, 3-dimethylxanthine derivatives WA Elgaher, AM Hayallah, OIA Salem, AAM Abdel Alim Bulletin of Pharmaceutical Sciences Assiut University 32 (1), 153-187, 2009 | 15 | 2009 |
| Cystobactamides S Baumann, J Herrmann, M Kathrin, H Steinmetz, K Gerth, R Ritesh, ... | 14 | 2021 |
| Discovery of novel latency-associated nuclear antigen inhibitors as antiviral agents against Kaposi’s sarcoma-associated herpesvirus P Kirsch, V Jakob, WAM Elgaher, C Walt, K Oberhausen, TF Schulz, ... ACS chemical biology 15 (2), 388-395, 2020 | 13 | 2020 |
| Identification of N, N-arylalkyl-picolinamide derivatives targeting the RNA-binding protein HuR, by combining biophysical fragment-screening and molecular hybridization S Della Volpe, P Linciano, R Listro, E Tumminelli, M Amadio, I Bonomo, ... Bioorganic Chemistry 116, 105305, 2021 | 11 | 2021 |
| NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner FH Waqas, M Shehata, WAM Elgaher, A Lacour, N Kurmasheva, ... PLoS Pathogens 19 (7), e1011506, 2023 | 8 | 2023 |
| Evaluation of Bacterial RNA Polymerase Inhibitors in a Staphylococcus aureus-Based Wound Infection Model in SKH1 Mice J Haupenthal, Y Kautz, WAM Elgaher, L Pätzold, T Röhrig, ... ACS infectious diseases 6 (10), 2573-2581, 2020 | 7 | 2020 |
