Neurturin, a relative of glial-cell-line-derived neurotrophic factor PT Kotzbauer, PA Lampe, RO Heuckeroth, JP Golden, DJ Creedon, ... Nature 384 (6608), 467-470, 1996 | 928 | 1996 |
Persephin, a novel neurotrophic factor related to GDNF and neurturin J Milbrandt, FJ De Sauvage, TJ Fahrner, RH Baloh, ML Leitner, ... Neuron 20 (2), 245-253, 1998 | 641 | 1998 |
GFRα1-deficient mice have deficits in the enteric nervous system and kidneys H Enomoto, T Araki, A Jackman, RO Heuckeroth, WD Snider, EM Johnson, ... Neuron 21 (2), 317-324, 1998 | 562 | 1998 |
TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret RH Baloh, MG Tansey, JP Golden, DJ Creedon, RO Heuckeroth, CL Keck, ... Neuron 18 (5), 793-802, 1997 | 449 | 1997 |
Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons Y Honma, T Araki, S Gianino, A Bruce, RO Heuckeroth, EM Johnson, ... Neuron 35 (2), 267-282, 2002 | 387 | 2002 |
Enteric nervous system development: migration, differentiation, and disease JI Lake, RO Heuckeroth American Journal of Physiology-Gastrointestinal and Liver Physiology 305 (1 …, 2013 | 384 | 2013 |
Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons RO Heuckeroth, H Enomoto, JR Grider, JP Golden, JA Hanke, A Jackman, ... Neuron 22 (2), 253-263, 1999 | 375 | 1999 |
RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons H Enomoto, PA Crawford, A Gorodinsky, RO Heuckeroth, EM Johnson Jr, ... Oxford University Press for The Company of Biologists Limited 128 (20), 3963 …, 2001 | 324 | 2001 |
GDNF availability determines enteric neuron number by controlling precursor proliferation S Gianino, JR Grider, J Cresswell, H Enomoto, RO Heuckeroth Oxford University Press for The Company of Biologists Limited 130 (10), 2187 …, 2003 | 303 | 2003 |
Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria. RJ Duronio, E Jackson-Machelski, RO Heuckeroth, PO Olins, CS Devine, ... Proceedings of the National Academy of Sciences 87 (4), 1506-1510, 1990 | 301 | 1990 |
The metabolic significance of mammalian fatty-acid-binding proteins: abundant proteins in search of a function DA Sweetser, RO Heuckeroth, JI Gordon Annual review of nutrition 7 (1), 337-359, 1987 | 296 | 1987 |
Neurturin and GDNF promote proliferation and survival of enteric neuron and glial progenitorsin vitro RO Heuckeroth, PA Lampe, EM Johnson Jr, J Milbrandt Developmental biology 200 (1), 116-129, 1998 | 281 | 1998 |
Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons DJ Creedon, MG Tansey, RH Baloh, PA Osborne, PA Lampe, TJ Fahrner, ... Proceedings of the National Academy of Sciences 94 (13), 7018-7023, 1997 | 267 | 1997 |
Analysis of the tissue-specific expression, developmental regulation, and linkage relationships of a rodent gene encoding heart fatty acid binding protein. RO Heuckeroth, EH Birkenmeier, MS Levin, JI Gordon Journal of Biological Chemistry 262 (20), 9709-9717, 1987 | 248 | 1987 |
Hirschsprung disease—integrating basic science and clinical medicine to improve outcomes RO Heuckeroth Nature reviews Gastroenterology & hepatology 15 (3), 152-167, 2018 | 247 | 2018 |
Disruption of the yeast N-myristoyl transferase gene causes recessive lethality RJ Duronio, DA Towler, RO Heuckeroth, JI Gordon Science 243 (4892), 796-800, 1989 | 237 | 1989 |
Unexpected roles for the second brain: enteric nervous system as master regulator of bowel function S Schneider, CM Wright, RO Heuckeroth Annual review of physiology 81, 235-259, 2019 | 177 | 2019 |
Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca XJ Song, DQ Li, W Farley, LH Luo, RO Heuckeroth, J Milbrandt, ... Investigative ophthalmology & visual science 44 (10), 4223-4229, 2003 | 150 | 2003 |
Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis S Jain, CK Naughton, M Yang, A Strickland, K Vij, M Encinas, J Golden, ... Oxford University Press for The Company of Biologists Limited 131 (21), 5503 …, 2004 | 147 | 2004 |
Building a second brain in the bowel M Avetisyan, EM Schill, RO Heuckeroth The Journal of clinical investigation 125 (3), 899-907, 2015 | 143 | 2015 |