Alex Aliper
Alex Aliper
Insilico Medicine
Подтвержден адрес электронной почты в домене insilico.com
Deep learning enables rapid identification of potent DDR1 kinase inhibitors
A Zhavoronkov, YA Ivanenkov, A Aliper, MS Veselov, VA Aladinskiy, ...
Nature biotechnology 37 (9), 1038-1040, 2019
Deep learning applications for predicting pharmacological properties of drugs and drug repurposing using transcriptomic data
A Aliper, S Plis, A Artemov, A Ulloa, P Mamoshina, A Zhavoronkov
Molecular pharmaceutics 13 (7), 2524-2530, 2016
druGAN: an advanced generative adversarial autoencoder model for de novo generation of new molecules with desired molecular properties in silico
A Kadurin, S Nikolenko, K Khrabrov, A Aliper, A Zhavoronkov
Molecular pharmaceutics 14 (9), 3098-3104, 2017
Converging blockchain and next-generation artificial intelligence technologies to decentralize and accelerate biomedical research and healthcare
P Mamoshina, L Ojomoko, Y Yanovich, A Ostrovski, A Botezatu, ...
Oncotarget 9 (5), 5665, 2018
Deep biomarkers of human aging: application of deep neural networks to biomarker development
E Putin, P Mamoshina, A Aliper, M Korzinkin, A Moskalev, A Kolosov, ...
Aging (Albany NY) 8 (5), 1021, 2016
The cornucopia of meaningful leads: Applying deep adversarial autoencoders for new molecule development in oncology
A Kadurin, A Aliper, A Kazennov, P Mamoshina, Q Vanhaelen, ...
Oncotarget 8 (7), 10883, 2017
Entangled conditional adversarial autoencoder for de novo drug discovery
D Polykovskiy, A Zhebrak, D Vetrov, Y Ivanenkov, V Aladinskiy, ...
Molecular pharmaceutics 15 (10), 4398-4405, 2018
Genetics and epigenetics of aging and longevity
A Moskalev, A Aliper, Z Smit-McBride, A Buzdin, A Zhavoronkov
Cell Cycle 13 (7), 1063-1077, 2014
Potential 2019-nCoV 3C-like protease inhibitors designed using generative deep learning approaches
A Zhavoronkov, V Aladinskiy, A Zhebrak, B Zagribelnyy, V Terentiev, ...
Adversarial Threshold Neural Computer for Molecular de Novo Design
E Putin, A Asadulaev, Q Vanhaelen, Y Ivanenkov, AV Aladinskaya, ...
Molecular pharmaceutics 15 (10), 4386-4397, 2018
Population specific biomarkers of human aging: a big data study using South Korean, Canadian, and Eastern European patient populations
P Mamoshina, K Kochetov, E Putin, F Cortese, A Aliper, WS Lee, SM Ahn, ...
The Journals of Gerontology: Series A 73 (11), 1482-1490, 2018
Artificial intelligence for aging and longevity research: Recent advances and perspectives
A Zhavoronkov, P Mamoshina, Q Vanhaelen, M Scheibye-Knudsen, ...
Ageing research reviews 49, 49-66, 2019
DNA repair in species with extreme lifespan differences
SL MacRae, MMK Croken, RB Calder, A Aliper, B Milholland, RR White, ...
Aging (Albany NY) 7 (12), 1171, 2015
Molecular aspects of development and regulation of endometriosis
YB Aznaurova, MB Zhumataev, TK Roberts, AM Aliper, AA Zhavoronkov
Reproductive Biology and Endocrinology 12, 1-25, 2014
Design of efficient computational workflows for in silico drug repurposing
Q Vanhaelen, P Mamoshina, AM Aliper, A Artemov, K Lezhnina, I Ozerov, ...
Drug Discovery Today 22 (2), 210-222, 2017
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development
IV Ozerov, KV Lezhnina, E Izumchenko, AV Artemov, S Medintsev, ...
Nature communications 7 (1), 13427, 2016
A role for G‐CSF and GM‐CSF in nonmyeloid cancers
AM Aliper, VP Frieden‐Korovkina, A Buzdin, SA Roumiantsev, ...
Cancer medicine 3 (4), 737-746, 2014
Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities
F Galkin, P Mamoshina, A Aliper, JP de Magalhães, VN Gladyshev, ...
Ageing Research Reviews 60, 101050, 2020
Geroprotectors. org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease
A Moskalev, E Chernyagina, JP de Magalhães, D Barardo, H Thoppil, ...
Aging (Albany NY) 7 (9), 616, 2015
AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor
F Ren, X Ding, M Zheng, M Korzinkin, X Cai, W Zhu, A Mantsyzov, ...
Chemical Science 14 (6), 1443-1452, 2023
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