A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress O Brandman, J Stewart-Ornstein, D Wong, A Larson, CC Williams, GW Li, ... Cell 151 (5), 1042-1054, 2012 | 646 | 2012 |
Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains PS Shen, J Park, Y Qin, X Li, K Parsawar, MH Larson, J Cox, Y Cheng, ... Science 347 (6217), 75-78, 2015 | 284 | 2015 |
The structure of the polycystic kidney disease channel PKD2 in lipid nanodiscs PS Shen, X Yang, PG DeCaen, X Liu, D Bulkley, DE Clapham, E Cao Cell 167 (3), 763-773. e11, 2016 | 270 | 2016 |
Structure of the Cdc48 segregase in the act of unfolding an authentic substrate I Cooney, H Han, MG Stewart, RH Carson, DT Hansen, JH Iwasa, ... Science 365 (6452), 502-505, 2019 | 147 | 2019 |
Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase N Monroe, H Han, PS Shen, WI Sundquist, CP Hill Elife 6, e24487, 2017 | 135 | 2017 |
Characterization of Pseudomonas chlororaphis myovirus 201ϕ2-1 via genomic sequencing, mass spectrometry, and electron microscopy JA Thomas, MR Rolando, CA Carroll, PS Shen, DM Belnap, ST Weintraub, ... Virology 376 (2), 330-338, 2008 | 118 | 2008 |
Vms1p is a release factor for the ribosome-associated quality control complex O Zurita Rendón, EK Fredrickson, CJ Howard, J Van Vranken, S Fogarty, ... Nature communications 9 (1), 2197, 2018 | 100 | 2018 |
The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets H Han, N Monroe, WI Sundquist, PS Shen, CP Hill Elife 6, e31324, 2017 | 93 | 2017 |
Dicer uses distinct modules for recognizing dsRNA termini NK Sinha, J Iwasa, PS Shen, BL Bass Science 359 (6373), 329-334, 2018 | 91 | 2018 |
The 2017 Nobel Prize in Chemistry: cryo-EM comes of age PS Shen Analytical and bioanalytical chemistry 410, 2053-2057, 2018 | 57 | 2018 |
Structural inhibition of dynamin-mediated membrane fission by endophilin A Hohendahl, N Talledge, V Galli, PS Shen, F Humbert, P De Camilli, ... Elife 6, e26856, 2017 | 45 | 2017 |
Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases H Han, JM Fulcher, VP Dandey, JH Iwasa, WI Sundquist, MS Kay, ... Elife 8, e44071, 2019 | 42 | 2019 |
Sequence and structural characterization of great salt lake bacteriophage CW02, a member of the T7-like supergroup PS Shen, MJ Domek, E Sanz-García, A Makaju, RM Taylor, R Hoggan, ... Journal of virology 86 (15), 7907-7917, 2012 | 42 | 2012 |
The structure of avian polyomavirus reveals variably sized capsids, non-conserved inter-capsomere interactions, and a possible location of the minor capsid protein VP4 PS Shen, D Enderlein, CDS Nelson, WS Carter, M Kawano, L Xing, ... Virology 411 (1), 142-152, 2011 | 41 | 2011 |
Active conformation of the p97-p47 unfoldase complex Y Xu, H Han, I Cooney, Y Guo, NG Moran, NR Zuniga, JC Price, CP Hill, ... Nature communications 13 (1), 2640, 2022 | 18 | 2022 |
Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome MG Rollins, M Shasmal, N Meade, H Astar, PS Shen, D Walsh Cell reports 36 (10), 2021 | 11 | 2021 |
Elongation of nascent chains PS Shen Science 1, 1, 2015 | 4 | 2015 |
Lysate-to-grid: Rapid Isolation of Native Complexes from Budding Yeast for Cryo-EM Imaging I Cooney, DC Mack, AJ Ferrell, MG Stewart, S Wang, HM Donelick, ... Bio-protocol 13 (2), e4596-e4596, 2023 | 1 | 2023 |
Visualization of the Cdc48 AAA+ ATPase protein unfolding pathway I Cooney, HL Schubert, K Cedeno, HJL Lin, JC Price, CP Hill, PS Shen bioRxiv, 2023.05. 13.540638, 2023 | 1 | 2023 |
Structural analysis of G protein β5 subunit folding by the cytosolic chaperonin CCT/TRiC and its co‐chaperone phosducin‐like protein 1 reveal molecular … M Sass, WG Ludlam, S Wang, Y Kwon, E Carter, J Bohman, PS Shen, ... The FASEB Journal 36, 2022 | 1 | 2022 |