PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility X Wang, D Winter, G Ashrafi, J Schlehe, YL Wong, D Selkoe, S Rice, ... Cell 147 (4), 893-906, 2011 | 1268 | 2011 |
Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation Z Zhou, EJ Hong, S Cohen, W Zhao, HH Ho, L Schmidt, WG Chen, Y Lin, ... Neuron 52 (2), 255-269, 2006 | 932 | 2006 |
The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc PL Greer, R Hanayama, BL Bloodgood, AR Mardinly, DM Lipton, ... Cell 140 (5), 704-716, 2010 | 732 | 2010 |
Tau PTM profiles identify patient heterogeneity and stages of Alzheimer’s disease H Wesseling, W Mair, M Kumar, CN Schlaffner, S Tang, P Beerepoot, ... Cell 183 (6), 1699-1713. e13, 2020 | 479 | 2020 |
Phosphorylation analysis by mass spectrometry: myths, facts, and the consequences for qualitative and quantitative measurements H Steen, JA Jebanathirajah, J Rush, N Morrice, MW Kirschner Molecular & Cellular Proteomics 5 (1), 172-181, 2006 | 407 | 2006 |
Posttranslational modifications mediate the structural diversity of tauopathy strains T Arakhamia, CE Lee, Y Carlomagno, M Kumar, DM Duong, H Wesseling, ... Cell 180 (4), 633-644. e12, 2020 | 359 | 2020 |
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease S Dujardin, C Commins, A Lathuiliere, P Beerepoot, AR Fernandes, ... Nature medicine 26 (8), 1256-1263, 2020 | 354 | 2020 |
Stable isotope-free relative and absolute quantitation of protein phosphorylation stoichiometry by MS H Steen, JA Jebanathirajah, M Springer, MW Kirschner Proceedings of the National Academy of Sciences 102 (11), 3948-3953, 2005 | 251 | 2005 |
Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits B Akten, MJ Kye, LT Hao, MH Wertz, S Singh, D Nie, J Huang, ... Proceedings of the National Academy of Sciences 108 (25), 10337-10342, 2011 | 250 | 2011 |
Robust prediction of the MASCOT score for an improved quality assessment in mass spectrometric proteomics T Koenig, BH Menze, M Kirchner, F Monigatti, KC Parker, T Patterson, ... Journal of proteome research 7 (9), 3708-3717, 2008 | 250 | 2008 |
Injury-induced decline of intrinsic regenerative ability revealed by quantitative proteomics S Belin, H Nawabi, C Wang, S Tang, A Latremoliere, P Warren, H Schorle, ... Neuron 86 (4), 1000-1014, 2015 | 246 | 2015 |
Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC NG Ayad, S Rankin, M Murakami, J Jebanathirajah, S Gygi, MW Kirschner Cell 113 (1), 101-113, 2003 | 212 | 2003 |
Pleiotropic effects of miR-183~ 96~ 182 converge to regulate cell survival, proliferation and migration in medulloblastoma SD Weeraratne, V Amani, N Teider, J Pierre-Francois, D Winter, MJ Kye, ... Acta neuropathologica 123, 539-552, 2012 | 190 | 2012 |
Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis CK Hu, N Özlü, M Coughlin, JJ Steen, TJ Mitchison Molecular biology of the cell 23 (14), 2702-2711, 2012 | 154 | 2012 |
FLEXIQuant: a novel tool for the absolute quantification of proteins, and the simultaneous identification and quantification of potentially modified peptides S Singh, M Springer, J Steen, MW Kirschner, H Steen Journal of proteome research 8 (5), 2201-2210, 2009 | 150 | 2009 |
FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease W Mair, J Muntel, K Tepper, S Tang, J Biernat, WW Seeley, KS Kosik, ... Analytical chemistry 88 (7), 3704-3714, 2016 | 135 | 2016 |
Human iPSC-derived neuronal model of tau-A152T frontotemporal dementia reveals tau-mediated mechanisms of neuronal vulnerability MC Silva, C Cheng, W Mair, S Almeida, H Fong, MHU Biswas, Z Zhang, ... Stem cell reports 7 (3), 325-340, 2016 | 112 | 2016 |
Global methods for protein glycosylation analysis by mass spectrometry BA Budnik, RS Lee, JAJ Steen Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1764 (12), 1870-1880, 2006 | 107 | 2006 |
NITPICK: peak identification for mass spectrometry data BY Renard, M Kirchner, H Steen, JAJ Steen, FA Hamprecht BMC bioinformatics 9, 1-16, 2008 | 104 | 2008 |
Doublecortin-like kinases promote neuronal survival and induce growth cone reformation via distinct mechanisms H Nawabi, S Belin, R Cartoni, PR Williams, C Wang, A Latremolière, ... Neuron 88 (4), 704-719, 2015 | 101 | 2015 |