Drug screening for ALS using patient-specific induced pluripotent stem cells N Egawa, S Kitaoka, K Tsukita, M Naitoh, K Takahashi, T Yamamoto, ... Science translational medicine 4 (145), 145ra104-145ra104, 2012 | 641 | 2012 |
Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease T Tokuda, MM Qureshi, MT Ardah, S Varghese, SAS Shehab, T Kasai, ... Neurology 75 (20), 1766-1770, 2010 | 576 | 2010 |
CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease L Matsumoto, H Takuma, A Tamaoka, H Kurisaki, H Date, S Tsuji, A Iwata PloS one 5 (11), e15522, 2010 | 352 | 2010 |
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy H Ishiura, K Doi, J Mitsui, J Yoshimura, MK Matsukawa, A Fujiyama, ... Nature genetics 50 (4), 581-590, 2018 | 288 | 2018 |
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis K Imamura, Y Izumi, A Watanabe, K Tsukita, K Woltjen, T Yamamoto, ... Science Translational Medicine 9 (391), eaaf3962, 2017 | 235 | 2017 |
APP717 missense mutation affects the ratio of amyloid beta protein species (A beta 1-42/43 and a beta 1-40) in familial Alzheimer's disease brain A Tamaoka, A Odaka, Y Ishibashi, M Usami, N Sahara, N Suzuki, ... Journal of Biological Chemistry 269 (52), 32721-32724, 1994 | 235 | 1994 |
Amyloid β protein in plasma from patients with sporadic Alzheimer's disease A Tamaoka, T Fukushima, N Sawamura, K Ishikawa, E Oguni, ... Journal of the neurological sciences 141 (1-2), 65-68, 1996 | 207 | 1996 |
Quantitation of amyloid beta-protein (A beta) in the cortex during aging and in Alzheimer's disease. H Funato, M Yoshimura, K Kusui, A Tamaoka, K Ishikawa, N Ohkoshi, ... The American journal of pathology 152 (6), 1633, 1998 | 205 | 1998 |
Amyloid β protein 42 (43) in cerebrospinal fluid of patients with Alzheimer's disease A Tamaoka, N Sawamura, T Fukushima, E Matsubara, M Shoji, S Hirai, ... Journal of the neurological sciences 148 (1), 41-45, 1997 | 203 | 1997 |
Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels. A Tamaoka, RN Kalaria, I Lieberburg, DJ Selkoe Proceedings of the National Academy of Sciences 89 (4), 1345-1349, 1992 | 178 | 1992 |
Biochemical evidence for the long-tail form (Aβ1-42/43) of amyloid β protein as a seed molecule in cerebral deposits of alzheimer′ s disease A Tamaoka, T Kondo, A Odaka, N Sahara, N Sawamura, K Ozawa, ... Biochemical and biophysical research communications 205 (1), 834-842, 1994 | 149 | 1994 |
Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation A Iwata, K Nagata, H Hatsuta, H Takuma, M Bundo, K Iwamoto, ... Human molecular genetics 23 (3), 648-656, 2014 | 147 | 2014 |
Plasma levels of amyloid β proteins Aβ1–40 and Aβ1–42 (43) are elevated in Down's syndrome T Tokuda, T Fukushima, SI Ikeda, Y Sekijima, SI Shoji, N Yanagisawa, ... Annals of Neurology: Official Journal of the American Neurological …, 1997 | 143 | 1997 |
Diphenylarsinic acid poisoning from chemical weapons in Kamisu, Japan K Ishii, A Tamaoka, F Otsuka, N Iwasaki, K Shin, A Matsui, G Endo, ... Annals of Neurology: Official Journal of the American Neurological …, 2004 | 118 | 2004 |
Molecular analysis and biochemical classification of TDP-43 proteinopathy H Tsuji, T Arai, F Kametani, T Nonaka, M Yamashita, M Suzukake, ... Brain 135 (11), 3380-3391, 2012 | 114 | 2012 |
Aβ1–40 but not Aβ1–42 levels in cortex correlate with apolipoprotein E ϵ4 allele dosage in sporadic Alzheimer's disease K Ishii, A Tamaoka, H Mizusawa, S Shoji, T Ohtake, PE Fraser, ... Brain research 748 (1-2), 250-252, 1997 | 111 | 1997 |
Sodium channel β4 subunit: down‐regulation and possible involvement in neuritic degeneration in Huntington's disease transgenic mice F Oyama, H Miyazaki, N Sakamoto, C Becquet, Y Machida, K Kaneko, ... Journal of neurochemistry 98 (2), 518-529, 2006 | 108 | 2006 |
Aβ42-positive non-pyramidal neurons around amyloid plaques in Alzheimer's disease A Mochizuki, A Tamaoka, A Shimohata, Y Komatsuzaki The Lancet 355 (9197), 42-43, 2000 | 108 | 2000 |
Apolipoprotein E allele–dependent antioxidant activity in brains with Alzheimer’s disease A Tamaoka, F Miyatake, S Matsuno, K Ishii, S Nagase, N Sahara, S Ono, ... Neurology 54 (12), 2319-2321, 2000 | 101 | 2000 |
Angiotensin-converting enzyme genotype is associated with Alzheimer disease in the Japanese population J Hu, F Miyatake, Y Aizu, H Nakagawa, S Nakamura, A Tamaoka, ... Neuroscience letters 277 (1), 65-67, 1999 | 101 | 1999 |