| Practically Useful: What the Rosetta Protein Modeling Suite Can Do for You KW Kaufmann, GH Lemmon, SL DeLuca, JH Sheehan, J Meiler Biochemistry 49 (14), 2987-2998, 2010 | 539 | 2010 |
| Small-molecule ligand docking into comparative models with Rosetta SA Combs, SL DeLuca, SH DeLuca, GH Lemmon, DP Nannemann, ... Nature protocols 8 (7), 1277-1298, 2013 | 209 | 2013 |
| Protocols for molecular modeling with Rosetta3 and RosettaScripts BJ Bender, A Cisneros III, AM Duran, JA Finn, D Fu, AD Lokits, BK Mueller, ... Biochemistry 55 (34), 4748-4763, 2016 | 206 | 2016 |
| The role of Bruton’s tyrosine kinase in autoimmunity and implications for therapy LJ Crofford, LE Nyhoff, JH Sheehan, PL Kendall Expert review of clinical immunology 12 (7), 763-773, 2016 | 141 | 2016 |
| EGFR Fusions as Novel Therapeutic Targets in Lung Cancer K Konduri, JN Gallant, YK Chae, FJ Giles, BJ Gitlitz, K Gowen, E Ichihara, ... Cancer discovery 6 (6), 601-611, 2016 | 127 | 2016 |
| EGFR Kinase Domain Duplication (EGFR-KDD) Is a Novel Oncogenic Driver in Lung Cancer That Is Clinically Responsive to Afatinib JN Gallant, JH Sheehan, TM Shaver, M Bailey, D Lipson, ... Cancer discovery 5 (11), 1155-1163, 2015 | 126 | 2015 |
| Inhibitors of the HIV-1 capsid, a target of opportunity SK Carnes, JH Sheehan, C Aiken Current Opinion in HIV and AIDS 13 (4), 359-365, 2018 | 121 | 2018 |
| An Acquired HER2 T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant–Driven Breast Cancer AB Hanker, MR Brewer, JH Sheehan, JP Koch, GR Sliwoski, R Nagy, ... Cancer discovery 7 (6), 575-585, 2017 | 106* | 2017 |
| NFI transcription factors interact with FOXA1 to regulate prostate-specific gene expression MM Grabowska, AD Elliott, DJ DeGraff, PD Anderson, G Anumanthan, ... Molecular endocrinology 28 (6), 949-964, 2014 | 81 | 2014 |
| Comprehensive analysis of constraint on the spatial distribution of missense variants in human protein structures RM Sivley, X Dou, J Meiler, WS Bush, JA Capra The American Journal of Human Genetics 102 (3), 415-426, 2018 | 75 | 2018 |
| The mode of action of centrin: binding of Ca2+ and a peptide fragment of Kar1p to the C-terminal domain H Hu, JH Sheehan, WJ Chazin Journal of Biological Chemistry 279 (49), 50895-50903, 2004 | 69 | 2004 |
| Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity AB Hanker, BP Brown, J Meiler, A Marín, HS Jayanthan, D Ye, CC Lin, ... Cancer cell 39 (8), 1099-1114. e8, 2021 | 66 | 2021 |
| Tailoring peptidomimetics for targeting protein–protein interactions ON Akram, DJ DeGraff, JH Sheehan, WD Tilley, RJ Matusik, JM Ahn, ... Molecular Cancer Research 12 (7), 967-978, 2014 | 65 | 2014 |
| The Kir channel immunoglobulin domain is essential for Kir1. 1 (ROMK) thermodynamic stability, trafficking and gating K Fallen, S Banerjee, J Sheehan, D Addison, LM Lewis, J Meiler, ... Channels 3 (1), 57-68, 2009 | 65 | 2009 |
| Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects R Yang, J Shi, IJL Byeon, J Ahn, JH Sheehan, J Meiler, AM Gronenborn, ... Retrovirology 9, 1-14, 2012 | 64 | 2012 |
| Glycosylation of β2 subunits regulates GABAA receptor biogenesis and channel gating W Lo, AH Lagrange, CC Hernandez, R Harrison, A Dell, SM Haslam, ... Journal of Biological Chemistry 285 (41), 31348-31361, 2010 | 52 | 2010 |
| Thermogelling bioadhesive scaffolds for intervertebral disk tissue engineering: preliminary in vitro comparison of aldehyde-based versus alginate microparticle-mediated adhesion C Wiltsey, T Christiani, J Williams, J Scaramazza, C Van Sciver, K Toomer, ... Acta biomaterialia 16, 71-80, 2015 | 48 | 2015 |
| Measurement of aptamer–protein interactions with back-scattering interferometry IR Olmsted, Y Xiao, M Cho, AT Csordas, JH Sheehan, J Meiler, HT Soh, ... Analytical chemistry 83 (23), 8867-8870, 2011 | 48 | 2011 |
| Loop–loop interactions regulate KaiA-stimulated KaiC phosphorylation in the cyanobacterial KaiABC circadian clock M Egli, R Pattanayek, JH Sheehan, Y Xu, T Mori, JA Smith, CH Johnson Biochemistry 52 (7), 1208-1220, 2013 | 46 | 2013 |
| Modeling immunity with Rosetta: methods for antibody and antigen design CT Schoeder, S Schmitz, J Adolf-Bryfogle, AM Sevy, JA Finn, MF Sauer, ... Biochemistry 60 (11), 825-846, 2021 | 40 | 2021 |
Jens MeilerVanderbilt University & University LeipzigVerified email at meilerlab.org
