Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers KB Kuchenbaecker, JL Hopper, DR Barnes, KA Phillips, TM Mooij, ... Jama 317 (23), 2402-2416, 2017 | 2970 | 2017 |
Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial J Burn, AM Gerdes, F Macrae, JP Mecklin, G Moeslein, S Olschwang, ... The Lancet 378 (9809), 2081-2087, 2011 | 1154 | 2011 |
Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) N Mavaddat, D Barrowdale, IL Andrulis, SM Domchek, D Eccles, ... Cancer Epidemiology, Biomarkers & Prevention 21 (1), 134-147, 2012 | 792 | 2012 |
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ... Nature genetics 45 (4), 371-384, 2013 | 660 | 2013 |
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer TR Rebbeck, N Mitra, F Wan, OM Sinilnikova, S Healey, L McGuffog, ... Jama 313 (13), 1347-1361, 2015 | 581 | 2015 |
Diagnostic criteria for constitutional mismatch repair deficiency syndrome: suggestions of the European consortium ‘care for CMMRD’(C4CMMRD) K Wimmer, CP Kratz, HFA Vasen, O Caron, C Colas, N Entz-Werle, ... Journal of medical genetics 51 (6), 355-365, 2014 | 455 | 2014 |
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ... Nature genetics 49 (5), 680-691, 2017 | 437 | 2017 |
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general … AC Antoniou, X Wang, ZS Fredericksen, L McGuffog, R Tarrell, ... Nature genetics 42 (10), 885-892, 2010 | 407 | 2010 |
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ... Nature genetics 49 (12), 1767-1778, 2017 | 397 | 2017 |
Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers AC Antoniou, AB Spurdle, OM Sinilnikova, S Healey, KA Pooley, ... The American Journal of Human Genetics 82 (4), 937-948, 2008 | 373 | 2008 |
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers KB Kuchenbaecker, L McGuffog, D Barrowdale, A Lee, P Soucy, J Dennis, ... JNCI: Journal of the National Cancer Institute 109 (7), djw302, 2017 | 343 | 2017 |
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk FJ Couch, X Wang, L McGuffog, A Lee, C Olswold, KB Kuchenbaecker, ... PLoS genetics 9 (3), e1003212, 2013 | 340 | 2013 |
Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind … J Burn, H Sheth, F Elliott, L Reed, F Macrae, JP Mecklin, G Möslein, ... The Lancet 395 (10240), 1855-1863, 2020 | 328 | 2020 |
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations TR Rebbeck, TM Friebel, E Friedman, U Hamann, D Huo, A Kwong, ... Human mutation 39 (5), 593-620, 2018 | 318 | 2018 |
Identification of six new susceptibility loci for invasive epithelial ovarian cancer KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, ... Nature genetics 47 (2), 164-171, 2015 | 317 | 2015 |
Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4 P Johansson, LG Aoude, K Wadt, WJ Glasson, SK Warrier, AW Hewitt, ... Oncotarget 7 (4), 4624, 2016 | 316 | 2016 |
Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction AC Antoniou, J Beesley, L McGuffog, OM Sinilnikova, S Healey, ... Cancer research 70 (23), 9742-9754, 2010 | 258 | 2010 |
Tamoxifen and Risk of Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers KA Phillips, RL Milne, MA Rookus, MB Daly, AC Antoniou, S Peock, ... Journal of clinical oncology 31 (25), 3091-3099, 2013 | 237 | 2013 |
Oral Contraceptives and Breast Cancer Risk in the International BRCA1/2 Carrier Cohort Study: A Report From EMBRACE, GENEPSO, GEO-HEBON, and the … RM Brohet, DE Goldgar, DF Easton, AC Antoniou, N Andrieu, ... Journal of clinical oncology 25 (25), 3831-3836, 2007 | 233 | 2007 |
Functional significance and clinical phenotype of nontruncating mismatch repair variants of MLH1 TE Raevaara, MK Korhonen, H Lohi, H Hampel, E Lynch, KE Lönnqvist, ... Gastroenterology 129 (2), 537-549, 2005 | 229 | 2005 |