Gwo-Yu Chuang
Gwo-Yu Chuang
Vaccine Research Center, NIAID/NIH
Verified email at
Cited by
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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ...
Nature 480 (7377), 336-343, 2011
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
M Pancera, T Zhou, A Druz, IS Georgiev, C Soto, J Gorman, J Huang, ...
Nature 514 (7523), 455-461, 2014
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus
JS McLellan, M Chen, MG Joyce, M Sastry, GBE Stewart-Jones, Y Yang, ...
science 342 (6158), 592-598, 2013
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface
J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ...
Nature 515 (7525), 138-142, 2014
Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques
R Brenke, D Kozakov, GY Chuang, D Beglov, D Hall, MR Landon, ...
Bioinformatics 25 (5), 621-627, 2009
Trimeric HIV-1-Env structures define glycan shields from clades A, B, and G
GBE Stewart-Jones, C Soto, T Lemmin, GY Chuang, A Druz, R Kong, ...
Cell 165 (4), 813-826, 2016
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies
T Zhou, J Zhu, X Wu, S Moquin, B Zhang, P Acharya, IS Georgiev, ...
Immunity 39 (2), 245-258, 2013
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ...
Nature structural & molecular biology 22 (7), 522-531, 2015
Identification of a CD4-binding-site antibody to HIV that evolved near-pan neutralization breadth
J Huang, BH Kang, E Ishida, T Zhou, T Griesman, Z Sheng, F Wu, ...
Immunity 45 (5), 1108-1121, 2016
Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo
RS Rudicell, YD Kwon, SY Ko, A Pegu, MK Louder, IS Georgiev, X Wu, ...
Journal of virology 88 (21), 12669-12682, 2014
Structural conservation of druggable hot spots in protein–protein interfaces
D Kozakov, DR Hall, GY Chuang, R Cencic, R Brenke, LE Grove, ...
Proceedings of the National Academy of Sciences 108 (33), 13528-13533, 2011
Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera
JO Ngwuta, M Chen, K Modjarrad, MG Joyce, M Kanekiyo, A Kumar, ...
Science translational medicine 7 (309), 309ra162-309ra162, 2015
Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody
M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ...
Cell 165 (2), 449-463, 2016
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
R Kong, K Xu, T Zhou, P Acharya, T Lemmin, K Liu, G Ozorowski, C Soto, ...
Science 352 (6287), 828-833, 2016
Vaccine-induced antibodies that neutralize group 1 and group 2 influenza A viruses
MG Joyce, AK Wheatley, PV Thomas, GY Chuang, C Soto, RT Bailer, ...
Cell 166 (3), 609-623, 2016
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization
IS Georgiev, NA Doria-Rose, T Zhou, Y Do Kwon, RP Staupe, S Moquin, ...
Science 340 (6133), 751-756, 2013
Maturation and diversity of the VRC01-antibody lineage over 15 years of chronic HIV-1 infection
X Wu, Z Zhang, CA Schramm, MG Joyce, Y Do Kwon, T Zhou, Z Sheng, ...
Cell 161 (3), 470-485, 2015
New member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency
NA Doria-Rose, JN Bhiman, RS Roark, CA Schramm, J Gorman, ...
Journal of virology 90 (1), 76-91, 2016
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
K Xu, P Acharya, R Kong, C Cheng, GY Chuang, K Liu, MK Louder, ...
Nature medicine 24 (6), 857-867, 2018
Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques
H Li, S Wang, R Kong, W Ding, FH Lee, Z Parker, E Kim, GH Learn, ...
Proceedings of the National Academy of Sciences 113 (24), E3413-E3422, 2016
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