A combinatorial approach to 2, 4, 6-trisubstituted triazines with potent antimalarial activity: combining conventional synthesis and microwave-assistance S Melato, D Prosperi, P Coghi, N Basilico, D Monti ChemMedChem 3 (6), 873-876, 2008 | 104 | 2008 |
Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action RK Haynes, WC Chan, HN Wong, KY Li, WK Wu, KM Fan, HHY Sung, ... ChemMedChem 5 (8), 1282-1299, 2010 | 102 | 2010 |
Considerations on the mechanism of action of artemisinin antimalarials: Part 1-The'carbon radical'and'heme'hypotheses R K Haynes, KW Cheu, D N'Da, P Coghi, D Monti Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2013 | 101 | 2013 |
Interactions between artemisinins and other antimalarial drugs in relation to the cofactor model—a unifying proposal for drug action RK Haynes, KW Cheu, HW Chan, HN Wong, KY Li, MMK Tang, MJ Chen, ... ChemMedChem 7 (12), 2204-2226, 2012 | 80 | 2012 |
Novel peroxides as promising anticancer agents with unexpected depressed antimalarial activity P Coghi, IA Yaremenko, P Prommana, PS Radulov, MA Syroeshkin, ... ChemMedChem 13 (9), 902-908, 2018 | 66 | 2018 |
Reactions of antimalarial peroxides with each of leucomethylene blue and dihydroflavins: flavin reductase and the cofactor model exemplified RK Haynes, KW Cheu, MMK Tang, MJ Chen, ZF Guo, ZH Guo, P Coghi, ... ChemMedChem 6 (2), 279-291, 2011 | 58 | 2011 |
Corilagin prevents SARS-CoV-2 infection by targeting RBD-ACE2 binding LJ Yang, RH Chen, S Hamdoun, P Coghi, JPL Ng, DW Zhang, X Guo, ... Phytomedicine 87, 153591, 2021 | 51 | 2021 |
Synthetic Peroxides Promote Apoptosis of Cancer Cells by Inhibiting P‐Glycoprotein ABCB5 IA Yaremenko, P Coghi, P Prommana, C Qiu, PS Radulov, Y Qu, ... ChemMedChem 15 (13), 1118-1127, 2020 | 39 | 2020 |
A partial convergence in action of methylene blue and artemisinins: antagonism with chloroquine, a reversal with verapamil, and an insight into the antimalarial activity of … RK Haynes, KW Cheu, KY Li, MMK Tang, HN Wong, MJ Chen, ZF Guo, ... ChemMedChem 6 (9), 1603-1615, 2011 | 37 | 2011 |
Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death BYK Law, F Gordillo-Martinez, YQ Qu, N Zhang, SW Xu, PS Coghi, ... Oncotarget 8 (18), 30077, 2017 | 36 | 2017 |
Organoboron compounds: Effective antibacterial and antiparasitic agents PS Coghi, Y Zhu, H Xie, NS Hosmane, Y Zhang Molecules 26 (11), 3309, 2021 | 34 | 2021 |
Interaction of Artemisinins with Oxyhemoglobin Hb–FeII, Hb–FeII, CarboxyHb–FeII, Heme–FeII, and Carboxyheme FeII: Significance for Mode of Action and … P Coghi, N Basilico, D Taramelli, WC Chan, RK Haynes, D Monti ChemMedChem 4 (12), 2045-2053, 2009 | 34 | 2009 |
Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol SW Xu, BYK Law, SWF Mok, ELH Leung, XX Fan, PS Coghi, W Zeng, ... International journal of oncology 49 (4), 1576-1588, 2016 | 31 | 2016 |
Semi-synthetic isoflavones as BACE-1 inhibitors against Alzheimer’s disease G Ribaudo, P Coghi, E Zanforlin, BYK Law, YYJ Wu, Y Han, AC Qiu, ... Bioorganic Chemistry 87, 474-483, 2019 | 30 | 2019 |
Next generation of boron neutron capture therapy (BNCT) agents for cancer treatment P Coghi, J Li, NS Hosmane, Y Zhu Medicinal Research Reviews 43 (5), 1809-1830, 2023 | 28 | 2023 |
N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca2+ Mobilization BYK Law, SWF Mok, J Chen, F Michelangeli, ZH Jiang, Y Han, YQ Qu, ... Frontiers in pharmacology 8, 388, 2017 | 26 | 2017 |
Antiplasmodial and anti-inflammatory activities of Canthium henriquesianum (K. Schum), a plant used in traditional medicine in Burkina Faso DP Ilboudo, N Basilico, S Parapini, Y Corbett, S D’Alessandro, M Dell’Agli, ... Journal of ethnopharmacology 148 (3), 763-769, 2013 | 22 | 2013 |
Computational and experimental insights on the interaction of artemisinin, dihydroartemisinin and chloroquine with SARS-CoV-2 spike protein receptor-binding domain (RBD) G Ribaudo, P Coghi, LJ Yang, JPL Ng, A Mastinu, M Memo, VKW Wong, ... Natural product research 36 (20), 5358-5363, 2022 | 20 | 2022 |
Parallel synthesis and antileishmanial activity of ether-linked phospholipids P Coghi, N Vaiana, MG Pezzano, L Rizzi, M Kaiser, R Brun, S Romeo Bioorganic & medicinal chemistry letters 18 (16), 4658-4660, 2008 | 20 | 2008 |
Antiproliferative activity of secondary metabolites from Zanthoxylum zanthoxyloides Lam: in vitro and in silico studies M Andima, P Coghi, LJ Yang, VKW Wong, CM Ngule, M Heydenreich, ... Pharmacognosy Comm 10, 44-51, 2020 | 19 | 2020 |