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Alena Savonenko
Alena Savonenko
Associate Professor, Pathology Department, Johns Hopkins University School of Medicine
Подтвержден адрес электронной почты в домене jhmi.edu
Название
Процитировано
Процитировано
Год
BACE1, a major determinant of selective vulnerability of the brain to amyloid-β amyloidogenesis, is essential for cognitive, emotional, and synaptic functions
FM Laird, H Cai, AV Savonenko, MH Farah, K He, T Melnikova, H Wen, ...
Journal of Neuroscience 25 (50), 11693-11709, 2005
6812005
Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease
JL Jankowsky, T Melnikova, DJ Fadale, GM Xu, HH Slunt, V Gonzales, ...
Journal of Neuroscience 25 (21), 5217-5224, 2005
6342005
Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to β-amyloid deposition and neurotransmitter abnormalities
A Savonenko, GM Xu, T Melnikova, JL Morton, V Gonzales, MPF Wong, ...
Neurobiology of disease 18 (3), 602-617, 2005
4772005
Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice
AV Savonenko, T Melnikova, FM Laird, KA Stewart, DL Price, PC Wong
Proceedings of the National Academy of Sciences 105 (14), 5585-5590, 2008
3422008
Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice
KI Andreasson, A Savonenko, S Vidensky, JJ Goellner, Y Zhang, ...
Journal of Neuroscience 21 (20), 8198-8209, 2001
2822001
A mouse model of blast injury to brain: initial pathological, neuropathological, and behavioral characterization
VE Koliatsos, I Cernak, L Xu, Y Song, A Savonenko, BJ Crain, ...
Journal of Neuropathology & Experimental Neurology 70 (5), 399-416, 2011
2652011
Persistent amyloidosis following suppression of Aβ production in a transgenic model of Alzheimer disease
JL Jankowsky, HH Slunt, V Gonzales, AV Savonenko, JC Wen, ...
PLoS medicine 2 (12), e355, 2005
2482005
Effectiveness of estrogen replacement in restoration of cognitive function after long-term estrogen withdrawal in aging rats
AL Markowska, AV Savonenko
Journal of neuroscience 22 (24), 10985-10995, 2002
2442002
Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease
Y Liu, MJ Yoo, A Savonenko, W Stirling, DL Price, DR Borchelt, ...
Journal of Neuroscience 28 (51), 13805-13814, 2008
2252008
Morphometry of the human substantia nigra in ageing and Parkinson’s disease
G Rudow, R O’Brien, AV Savonenko, SM Resnick, AB Zonderman, ...
Acta neuropathologica 115, 461-470, 2008
2162008
NPTX2 and cognitive dysfunction in Alzheimer’s Disease
MF Xiao, D Xu, MT Craig, KA Pelkey, CC Chien, Y Shi, J Zhang, ...
Elife 6, e23798, 2017
2052017
The cognitive effects of ovariectomy and estrogen replacement are modulated by aging
AV Savonenko, AL Markowska
Neuroscience 119 (3), 821-830, 2003
1692003
PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)
AG Horti, R Naik, CA Foss, IL Minn, V Misheneva, Y Du, Y Wang, ...
Proceedings of the National Academy of Sciences 116 (5), 1686-1691, 2019
1682019
Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer’s disease in a sex-dimorphic pattern
T Melnikova, A Savonenko, Q Wang, X Liang, T Hand, L Wu, ...
Neuroscience 141 (3), 1149-1162, 2006
1522006
RETRACTED: Enhanced polyubiquitination of shank3 and NMDA receptor in a mouse model of Autism
MA Bangash, JM Park, T Melnikova, D Wang, SK Jeon, D Lee, S Syeda, ...
Cell 145 (5), 758-772, 2011
1462011
Synthesis and biodistribution of [11C] A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2)
AG Horti, Y Gao, HT Ravert, P Finley, H Valentine, DF Wong, CJ Endres, ...
Bioorganic & medicinal chemistry 18 (14), 5202-5207, 2010
1222010
Inhibition of neutral sphingomyelinase‐2 perturbs brain sphingolipid balance and spatial memory in mice
N Tabatadze, A Savonenko, H Song, VVR Bandaru, M Chu, NJ Haughey
Journal of neuroscience research 88 (13), 2940-2951, 2010
1162010
Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice
G Schilling, AV Savonenko, A Klevytska, JL Morton, SM Tucker, M Poirier, ...
Human molecular genetics 13 (15), 1599-1610, 2004
1162004
Cannabinoid CB2 receptors in a mouse model of Aβ amyloidosis: immunohistochemical analysis and suitability as a PET biomarker of neuroinflammation
AV Savonenko, T Melnikova, Y Wang, H Ravert, Y Gao, J Koppel, D Lee, ...
PloS one 10 (6), e0129618, 2015
1152015
Amyloid precursor protein increases cortical neuron size in transgenic mice
ES Oh, AV Savonenko, JF King, SMF Tucker, GL Rudow, G Xu, ...
Neurobiology of aging 30 (8), 1238-1244, 2009
1092009
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Статьи 1–20