Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis MM Mihaylova, DS Vasquez, K Ravnskjaer, PD Denechaud, TY Ruth, ... Cell 145 (4), 607-621, 2011 | 601 | 2011 |
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans F Benhamed, PD Denechaud, M Lemoine, C Robichon, M Moldes, ... The Journal of clinical investigation 122 (6), 2176-2194, 2012 | 419 | 2012 |
ChREBP, a transcriptional regulator of glucose and lipid metabolism C Postic, R Dentin, PD Denechaud, J Girard Annu. Rev. Nutr. 27, 179-192, 2007 | 310 | 2007 |
ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver PD Denechaud, P Bossard, JMA Lobaccaro, L Millatt, B Staels, J Girard, ... The Journal of clinical investigation 118 (3), 956-964, 2008 | 256 | 2008 |
Role of ChREBP in hepatic steatosis and insulin resistance PD Denechaud, R Dentin, J Girard, C Postic FEBS letters 582 (1), 68-73, 2008 | 198 | 2008 |
E2F1, a novel regulator of metabolism PD Denechaud, L Fajas, A Giralt Frontiers in endocrinology 8, 307580, 2017 | 183 | 2017 |
T‐cell factor 4 and β‐catenin chromatin occupancies pattern zonal liver metabolism in mice A Gougelet, C Torre, P Veber, C Sartor, L Bachelot, PD Denechaud, ... Hepatology 59 (6), 2344-2357, 2014 | 172 | 2014 |
E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis PD Denechaud, IC Lopez-Mejia, A Giralt, Q Lai, E Blanchet, ... The Journal of clinical investigation 126 (1), 137-150, 2016 | 124 | 2016 |
Hepatic gene regulation by glucose and polyunsaturated fatty acids: a role for ChREBP R Dentin, PD Denechaud, F Benhamed, J Girard, C Postic The Journal of nutrition 136 (5), 1145-1149, 2006 | 107 | 2006 |
CDK4 is an essential insulin effector in adipocytes S Lagarrigue, IC Lopez-Mejia, PD Denechaud, X Escoté, ... The Journal of clinical investigation 126 (1), 335-348, 2022 | 84 | 2022 |
CDK4 phosphorylates AMPKα2 to inhibit its activity and repress fatty acid oxidation IC Lopez-Mejia, S Lagarrigue, A Giralt, L Martinez-Carreres, N Zanou, ... Molecular cell 68 (2), 336-349. e6, 2017 | 72 | 2017 |
β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue E Somm, H Henry, SJ Bruce, S Aeby, M Rosikiewicz, GP Sykiotis, M Asrih, ... JCI insight 2 (8), 2017 | 58 | 2017 |
Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity P Morigny, M Houssier, A Mairal, C Ghilain, E Mouisel, F Benhamed, ... Nature Metabolism 1 (1), 133-146, 2019 | 53 | 2019 |
E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver Q Lai, A Giralt, C Le May, L Zhang, B Cariou, PD Denechaud, L Fajas JCI insight 2 (10), 2017 | 49 | 2017 |
Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR D Castellano-Castillo, PD Denechaud, L Fajas, I Moreno-Indias, ... PloS one 14 (4), e0215083, 2019 | 39 | 2019 |
E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes A Giralt, PD Denechaud, IC Lopez-Mejia, B Delacuisine, E Blanchet, ... Molecular metabolism 11, 104-112, 2018 | 34 | 2018 |
Carbohydrate responsive element binding protein and lipid homeostasis PD Denechaud, J Girard, C Postic Current opinion in lipidology 19 (3), 301-306, 2008 | 30 | 2008 |
KAT2B is required for pancreatic beta cell adaptation to metabolic stress by controlling the unfolded protein response N Rabhi, PD Denechaud, X Gromada, SA Hannou, H Zhang, T Rashid, ... Cell reports 15 (5), 1051-1061, 2016 | 24 | 2016 |
Growth factor receptor binding protein 14 inhibition triggers insulin‐induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma L Morzyglod, M Caüzac, L Popineau, PD Denechaud, L Fajas, ... Hepatology 65 (4), 1352-1368, 2017 | 22 | 2017 |
Untargeted lipidomic profiling of dry blood spots using SFC-HRMS P Le Faouder, J Soullier, M Tremblay-Franco, A Tournadre, JF Martin, ... Metabolites 11 (5), 305, 2021 | 14 | 2021 |