Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing–induced congestive heart failure D Li, K Shinagawa, L Pang, TK Leung, S Cardin, Z Wang, S Nattel Circulation 104 (21), 2608-2614, 2001 | 1027 | 2001 |
International multisite study of human-induced pluripotent stem cell-derived cardiomyocytes for drug proarrhythmic potential assessment K Blinova, Q Dang, D Millard, G Smith, J Pierson, L Guo, M Brock, HR Lu, ... Cell reports 24 (13), 3582-3592, 2018 | 314 | 2018 |
Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias K Blinova, J Stohlman, J Vicente, D Chan, L Johannesen, ... Toxicological Sciences 155 (1), 234-247, 2017 | 255 | 2017 |
Evaluation of batch variations in induced pluripotent stem cell-derived human cardiomyocytes from 2 major suppliers J Huo, A Kamalakar, X Yang, B Word, N Stockbridge, B Lyn-Cook, L Pang Toxicological Sciences 156 (1), 25-38, 2017 | 69 | 2017 |
Tissue‐specific expression of two human Cav1.2 isoforms under the control of distinct 5′ flanking regulatory elements L Pang, G Koren, Z Wang, S Nattel FEBS letters 546 (2-3), 349-354, 2003 | 60 | 2003 |
Workshop report: FDA workshop on improving cardiotoxicity assessment with human-relevant platforms L Pang, P Sager, X Yang, H Shi, F Sannajust, M Brock, JC Wu, ... Circulation research 125 (9), 855-867, 2019 | 57 | 2019 |
Sex-related differences in drug-induced QT prolongation and torsades de pointes: a new model system with human iPSC-CMs J Huo, F Wei, C Cai, B Lyn-Cook, L Pang Toxicological Sciences 167 (2), 360-374, 2019 | 50 | 2019 |
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations G Gintant, EP Kaushik, T Feaster, S Stoelzle-Feix, Y Kanda, T Osada, ... Regulatory toxicology and pharmacology 117, 104756, 2020 | 45 | 2020 |
Characterization of a putative insulin-responsive element and its binding protein (s) in rat angiotensinogen gene promoter: regulation by glucose and insulin X Chen, SL Zhang, L Pang, JG Filep, SS Tang, JR Ingelfinger, JSD Chan Endocrinology 142 (6), 2577-2585, 2001 | 44 | 2001 |
Use of human iPSC-CMs in nonclinical regulatory studies for cardiac safety assessment X Yang, AJS Ribeiro, L Pang, DG Strauss Toxicological Sciences 190 (2), 117-126, 2022 | 41 | 2022 |
Vascular smooth muscle-specific knockdown of the noncardiac form of the L-type calcium channel by microRNA-based short hairpin RNA as a potential antihypertensive therapy SW Rhee, JR Stimers, W Wang, L Pang Journal of Pharmacology and Experimental Therapeutics 329 (2), 775-782, 2009 | 40 | 2009 |
Reversal of microRNA dysregulation in an animal model of pulmonary hypertension IB Gubrij, AK Pangle, L Pang, LG Johnson PloS one 11 (1), e0147827, 2016 | 34 | 2016 |
Toxicity testing in the era of induced pluripotent stem cells: A perspective regarding the use of patient-specific induced pluripotent stem cell–derived cardiomyocytes for … L Pang Current Opinion in Toxicology 23, 50-55, 2020 | 27 | 2020 |
ATP‐binding cassette genes genotype and expression: a potential association with pancreatic cancer development and chemoresistance? L Pang, B Word, J Xu, H Wang, G Hammons, SM Huang, B Lyn-Cook Gastroenterology research and practice 2014 (1), 414931, 2014 | 27 | 2014 |
Characterization of the cardiac KCNE1 gene promoter Z Mustapha, L Pang, S Nattel Cardiovascular research 73 (1), 82-91, 2007 | 23 | 2007 |
Vascular-Specific Increase in Exon 1b-Encoded CaV1.2 Channels in Spontaneously Hypertensive Rats W Wang, N Saada, B Dai, L Pang, P Palade American journal of hypertension 19 (8), 823-831, 2006 | 22 | 2006 |
MicroRNA-mediated maturation of human pluripotent stem cell-derived cardiomyocytes: Towards a better model for cardiotoxicity? MC White, L Pang, X Yang Food and Chemical Toxicology 98, 17-24, 2016 | 19 | 2016 |
Effects of electrical stimulation on hiPSC-CM responses to classic ion channel blockers F Wei, M Pourrier, DG Strauss, N Stockbridge, L Pang Toxicological Sciences 174 (2), 254-265, 2020 | 17 | 2020 |
Angiotensin II upregulates Cav1. 2 protein expression in cultured arteries via endothelial H2O2 production W Wang, L Pang, P Palade Journal of vascular research 48 (1), 67-78, 2010 | 13 | 2010 |
Angiotensin II causes endothelial-dependent increase in expression of CaV1. 2 protein in cultured arteries W Wang, L Pang, P Palade European journal of pharmacology 599 (1-3), 117-120, 2008 | 11 | 2008 |