Metabolic reprogramming of stromal fibroblasts by melanoma exosome microRNA favours a pre-metastatic microenvironment SL Shu, Y Yang, CL Allen, O Maguire, H Minderman, A Sen, MJ Ciesielski, ... Scientific reports 8 (1), 12905, 2018 | 163 | 2018 |
IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts X Shen, S Shen, J Li, Q Hu, L Nie, C Tu, X Wang, DJ Poulsen, BC Orsburn, ... Proceedings of the National Academy of Sciences 115 (21), E4767-E4776, 2018 | 81 | 2018 |
A comparative study of evaluating missing value imputation methods in label-free proteomics L Jin, Y Bi, C Hu, J Qu, S Shen, X Wang, Y Tian Scientific reports 11 (1), 1760, 2021 | 77 | 2021 |
An IonStar experimental strategy for MS1 ion current-based quantification using ultrahigh-field orbitrap: reproducible, in-depth, and accurate protein measurement in large cohorts X Shen, S Shen, J Li, Q Hu, L Nie, C Tu, X Wang, B Orsburn, J Wang, J Qu Journal of proteome research 16 (7), 2445-2456, 2017 | 74 | 2017 |
Behavioral, circuitry, and molecular aberrations by region-specific deficiency of the high-risk autism gene Cul3 M Rapanelli, T Tan, W Wang, X Wang, ZJ Wang, P Zhong, L Frick, L Qin, ... Molecular Psychiatry 26 (5), 1491-1504, 2021 | 55 | 2021 |
Synthesis of heterocycle-modified betulinic acid derivatives as antitumor agents * Hai-Wei Cui a, 1, Yuan He b, 1, Jinhua Wang b, Wei Gao a, Ting Liu c, Min ... European Journal of Medicinal Chemistry 95, 240-248, 2015 | 50 | 2015 |
MS1 ion current‐based quantitative proteomics: A promising solution for reliable analysis of large biological cohorts X Wang, S Shen, SS Rasam, J Qu Mass spectrometry reviews 38 (6), 461-482, 2019 | 49 | 2019 |
Synthesis of Novel Heterocyclic Ring‐Fused 18β‐Glycyrrhetinic Acid Derivatives with Antitumor and Antimetastatic Activity C Gao, FJ Dai, HW Cui, SH Peng, Y He, X Wang, ZF Yi, WW Qiu Chemical Biology & Drug Design 84 (2), 223-233, 2014 | 44 | 2014 |
Targeting pyruvate carboxylase by a small molecule suppresses breast cancer progression Q Lin, Y He, X Wang, Y Zhang, M Hu, W Guo, Y He, T Zhang, L Lai, Z Sun, ... Advanced Science 7 (9), 1903483, 2020 | 42 | 2020 |
Surfactant cocktail-aided extraction/precipitation/on-pellet digestion strategy enables efficient and reproducible sample preparation for large-scale quantitative proteomics S Shen, B An, X Wang, SP Hilchey, J Li, J Cao, Y Tian, C Hu, L Jin, A Ng, ... Analytical chemistry 90 (17), 10350-10359, 2018 | 39 | 2018 |
Optimization of Search Engines and Postprocessing Approaches to Maximize Peptide and Protein Identification for High-Resolution Mass Data ‡ Chengjian Tu,*,†,‡,# Quanhu Sheng,§,# Jun Li,†,‡ Danjun Ma,∥ Xiaomeng ... Journal of Proteome Research, 2015 | 38 | 2015 |
Sensitive, high-throughput, and robust trapping-micro-LC-MS strategy for the quantification of biomarkers and antibody biotherapeutics M Zhang, B An, Y Qu, S Shen, W Fu, YJ Chen, X Wang, R Young, ... Analytical chemistry 90 (3), 1870-1880, 2018 | 33 | 2018 |
Mapping dynamic histone modification patterns during arsenic-induced malignant transformation of human bladder cells Y Ge, J Zhu, X Wang, N Zheng, C Tu, J Qu, X Ren Toxicology and applied pharmacology 355, 164-173, 2018 | 22 | 2018 |
Temporal effects of combined birinapant and paclitaxel on pancreatic cancer cells investigated via large-scale, ion-current-based quantitative proteomics (IonStar) X Wang, J Niu, J Li, X Shen, S Shen, RM Straubinger, J Qu Molecular & Cellular Proteomics 17 (4), 655-671, 2018 | 21 | 2018 |
LG-362B targets PML-RARα and blocks ATRA resistance of acute promyelocytic leukemia X Wang, Q Lin, F Lv, N Liu, Y Xu, M Liu, Y Chen, Z Yi Leukemia 30 (7), 1465-1474, 2016 | 21 | 2016 |
Ultra-high-resolution ionstar strategy enhancing accuracy and precision of MS1-based proteomics and an extensive comparison with state-of-the-art SWATH-MS in large-cohort … X Wang, L Jin, C Hu, S Shen, S Qian, M Ma, X Zhu, F Li, J Wang, Y Tian, ... Analytical chemistry 93 (11), 4884-4893, 2021 | 15 | 2021 |
Mutant Kras as a biomarker plays a favorable role in FL118-induced apoptosis, reactive oxygen species (ROS) production and modulation of Survivin, mcl-1 and XIAP in human … S Santha, X Ling, IAM Aljahdali, SS Rasam, X Wang, J Liao, J Wang, ... Cancers 12 (11), 3413, 2020 | 14 | 2020 |
Glucose Drives Growth Factor–Independent Esophageal Cancer Proliferation via Phosphohistidine–Focal Adhesion Kinase Signaling J Zhang, IH Gelman, E Katsuta, Y Liang, X Wang, J Li, J Qu, L Yan, ... Cellular and Molecular Gastroenterology and Hepatology 8 (1), 37-60, 2019 | 13 | 2019 |
High-throughput, sensitive LC-MS quantification of biotherapeutics and biomarkers using antibody-free, peptide-level, multiple-mechanism enrichment via strategic regulation of … B An, M Zhang, J Pu, S Shen, Y Qu, YJ Chen, S Huo, X Wang, JR Polli, ... Analytical chemistry 91 (5), 3475-3483, 2019 | 10 | 2019 |
PubAngioGen: a database and knowledge for angiogenesis and related diseases * Peng Li1,†, Yongrui Liu1,†, Huan Wang1,†, Yuan He1,†, Xue Wang1, Yundong ... Nucleic Acids Research, 2014 | 10* | 2014 |