CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database BP Alcock, W Huynh, R Chalil, KW Smith, AR Raphenya, MA Wlodarski, ... Nucleic acids research 51 (D1), D690-D699, 2023 | 664 | 2023 |
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy L Ejim, MA Farha, SB Falconer, J Wildenhain, BK Coombes, M Tyers, ... Nature chemical biology 7 (6), 348-350, 2011 | 585 | 2011 |
Drug repurposing for antimicrobial discovery MA Farha, ED Brown Nature microbiology 4 (4), 565-577, 2019 | 356 | 2019 |
Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance JM Stokes, CR MacNair, B Ilyas, S French, JP Côté, C Bouwman, ... Nature microbiology 2 (5), 1-8, 2017 | 329 | 2017 |
Strategies for target identification of antimicrobial natural products MA Farha, ED Brown Natural product reports 33 (5), 668-680, 2016 | 304 | 2016 |
Collapsing the proton motive force to identify synergistic combinations against Staphylococcus aureus MA Farha, CP Verschoor, D Bowdish, ED Brown Chemistry & biology 20 (9), 1168-1178, 2013 | 257 | 2013 |
Inhibition of WTA synthesis blocks the cooperative action of PBPs and sensitizes MRSA to β-lactams MA Farha, A Leung, EW Sewell, MA D’Elia, SE Allison, L Ejim, PM Pereira, ... ACS chemical biology 8 (1), 226-233, 2013 | 231 | 2013 |
Uncovering the hidden antibiotic potential of cannabis MA Farha, OM El-Halfawy, RT Gale, CR MacNair, LA Carfrae, X Zhang, ... ACS infectious diseases 6 (3), 338-346, 2020 | 139 | 2020 |
Bicarbonate alters bacterial susceptibility to antibiotics by targeting the proton motive force MA Farha, S French, JM Stokes, ED Brown ACS infectious diseases 4 (3), 382-390, 2017 | 125 | 2017 |
Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase MA Farha, TL Czarny, CL Myers, LJ Worrall, S French, DG Conrady, ... Proceedings of the National Academy of Sciences 112 (35), 11048-11053, 2015 | 112 | 2015 |
Physicochemical characteristics and droplet impact dynamics of superhydrophobic carbon nanotube arrays AI Aria, M Gharib Langmuir 30 (23), 6780-6790, 2014 | 93 | 2014 |
Potentiation of antibiotics against Gram-negative bacteria by polymyxin B analogue SPR741 from unique perturbation of the outer membrane S French, M Farha, MJ Ellis, Z Sameer, JP Côté, N Cotroneo, T Lister, ... ACS infectious diseases 6 (6), 1405-1412, 2019 | 90 | 2019 |
Chemical probes of Escherichia coli uncovered through chemical-chemical interaction profiling with compounds of known biological activity MA Farha, ED Brown Chemistry & biology 17 (8), 852-862, 2010 | 79 | 2010 |
Unconventional screening approaches for antibiotic discovery MA Farha, ED Brown Annals of the New York Academy of Sciences 1354 (1), 54-66, 2015 | 65 | 2015 |
Discovery of antibiotic adjuvants MA Farha, ED Brown Nature biotechnology 31 (2), 120-122, 2013 | 55 | 2013 |
Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites MA Farha, K Koteva, RT Gale, EW Sewell, GD Wright, ED Brown Bioorganic & medicinal chemistry letters 24 (3), 905-910, 2014 | 29 | 2014 |
Chemical genomic approaches to study model microbes CA Barker, MA Farha, ED Brown Chemistry & biology 17 (6), 624-632, 2010 | 29 | 2010 |
Potentiation of aminoglycoside activity in Pseudomonas aeruginosa by targeting the AmgRS envelope stress-responsive two-component system K Poole, C Gilmour, MA Farha, E Mullen, CHF Lau, ED Brown Antimicrobial agents and chemotherapy 60 (6), 3509-3518, 2016 | 25 | 2016 |
Overcoming acquired and native macrolide resistance with bicarbonate MA Farha, CR MacNair, LA Carfrae, SS El Zahed, MJ Ellis, HKR Tran, ... ACS Infectious Diseases 6 (10), 2709-2718, 2020 | 24 | 2020 |
Systems-level chemical biology to accelerate antibiotic drug discovery MA Farha, S French, ED Brown Accounts of Chemical Research 54 (8), 1909-1920, 2021 | 23 | 2021 |