| Mammalian Grb2 couple the EGF receptor to the Ras M Rozakis-Adcock, R Fernley, JD Wade, T Pawson, D Bowtell Nature 363, 83-86, 1993 | 1307 | 1993 |
| INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent J Kumagai, SY Hsu, H Matsumi, JS Roh, P Fu, JD Wade, RAD Bathgate, ... Journal of Biological Chemistry 277 (35), 31283-31286, 2002 | 468 | 2002 |
| Human relaxin gene 3 (H3) and the equivalent mouse relaxin (M3) gene: novel members of the relaxin peptide family RAD Bathgate, CS Samuel, TCD Burazin, S Layfield, AA Claasz, ... Journal of Biological Chemistry 277 (2), 1148-1157, 2002 | 440 | 2002 |
| Current challenges in peptide-based drug discovery L Otvos Jr, JD Wade Frontiers in Chemistry 2, 62, 2014 | 421 | 2014 |
| Paracrine regulation of mammalian oocyte maturation and male germ cell survival K Kawamura, J Kumagai, S Sudo, SY Chun, M Pisarska, H Morita, ... Proceedings of the National Academy of Sciences 101 (19), 7323-7328, 2004 | 394 | 2004 |
| Chemically modified and conjugated antimicrobial peptides against superbugs W Li, F Separovic, NM O'Brien-Simpson, JD Wade Chemical Society Reviews 50, 4932-4973, 2021 | 307 | 2021 |
| Amyloid-β peptide (Aβ) neurotoxicity is modulated by the rate of peptide aggregation: Aβ dimers and trimers correlate with neurotoxicity LW Hung, GD Ciccotosto, E Giannakis, DJ Tew, K Perez, CL Masters, ... Journal of Neuroscience 28 (46), 11950-11958, 2008 | 260 | 2008 |
| Vasopressin secretion: osmotic and hormonal regulation by the lamina terminalis MJ McKinley, ML Mathai, RM McAllen, RC McClear, RR Miselis, ... Journal of neuroendocrinology 16 (4), 340-347, 2004 | 259 | 2004 |
| Neurotoxic, redox-competent Alzheimer's β-amyloid is released from lipid membrane by methionine oxidation KJ Barnham, GD Ciccotosto, AK Tickler, FE Ali, DG Smith, NA Williamson, ... Journal of Biological Chemistry 278 (44), 42959-42965, 2003 | 242 | 2003 |
| Copper-mediated amyloid-β toxicity is associated with an intermolecular histidine bridge DP Smith, DG Smith, CC Curtain, JF Boas, JR Pilbrow, GD Ciccotosto, ... Journal of Biological Chemistry 281 (22), 15145-15154, 2006 | 233 | 2006 |
| Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones L Deng, C De la Fuente, P Fu, L Wang, R Donnelly, JD Wade, P Lambert, ... Virology 277 (2), 278-295, 2000 | 214 | 2000 |
| Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria W Li, J Tailhades, NM O’Brien-Simpson, F Separovic, L Otvos Jr, ... Amino Acids 46 (10), 2287-2294, 2014 | 206 | 2014 |
| Design and development of a peptide-based adiponectin receptor agonist for cancer treatment L Otvos, E Haspinger, F La Russa, F Maspero, P Graziano, I Kovalszky, ... BMC biotechnology 11, 1-14, 2011 | 204 | 2011 |
| INSL3 as a biomarker of Leydig cell functionality R Ivell, JD Wade, R Anand-Ivell Biology of Reproduction 88 (6), 147, 2013 | 194 | 2013 |
| DBU as an N alpha-deprotecting reagent for the fluorenylmethoxycarbonyl group in continuous flow solid-phase peptide synthesis. JD Wade, J Bedford, RC Sheppard, GW Tregear Peptide Research 4 (3), 194-199, 1991 | 192 | 1991 |
| Alzheimer disease β-amyloid activity mimics cholesterol oxidase L Puglielli, AL Friedlich, KDR Setchell, S Nagano, C Opazo, RA Cherny, ... The Journal of clinical investigation 115 (9), 2556-2563, 2005 | 165 | 2005 |
| Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo RAD Bathgate, F Lin, NF Hanson, L Otvos, A Guidolin, C Giannakis, ... Biochemistry 45 (3), 1043-1053, 2006 | 163 | 2006 |
| Modulation of hippocampal theta oscillations and spatial memory by relaxin-3 neurons of the nucleus incertus S Ma, FE Olucha-Bordonau, MA Hossain, F Lin, C Kuei, C Liu, JD Wade, ... Learning & Memory 16 (11), 730-742, 2009 | 160 | 2009 |
| R3 (BΔ23–27) R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization C Kuei, S Sutton, P Bonaventure, C Pudiak, J Shelton, J Zhu, ... Journal of Biological Chemistry 282 (35), 25425-25435, 2007 | 152 | 2007 |
| Physiological and pathophysiological influences on thirst MJ McKinley, MJ Cairns, DA Denton, G Egan, ML Mathai, A Uschakov, ... Physiology & behavior 81 (5), 795-803, 2004 | 152 | 2004 |
Laszlo OtvosOLPE, LLCVerified email at olpeconsulting.com
Laszlo OtvosOLPE, LLCVerified email at olpeconsulting.com