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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks M Stucki, JA Clapperton, D Mohammad, MB Yaffe, SJ Smerdon, ... Cell 123 (7), 1213-1226, 2005 | 1397 | 2005 |
The ankyrin repeat: a diversity of interactions on a common structural framework SG Sedgwick, SJ Smerdon Trends in biochemical sciences 24 (8), 311-316, 1999 | 1074 | 1999 |
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain AEH Elia, P Rellos, LF Haire, JW Chao, FJ Ivins, K Hoepker, ... Cell 115 (1), 83-95, 2003 | 877 | 2003 |
Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding K Rittinger, J Budman, J Xu, S Volinia, LC Cantley, SJ Smerdon, ... Molecular cell 4 (2), 153-166, 1999 | 623 | 1999 |
Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways B Xiao, SJ Smerdon, DH Jones, GG Dodson, Y Soneji, A Aitken, ... Nature 376 (6536), 188-191, 1995 | 601 | 1995 |
Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue K Rittinger, PA Walker, JF Eccleston, SJ Smerdon, SJ Gamblin Nature 389 (6652), 758-762, 1997 | 541 | 1997 |
The molecular basis of FHA domain: phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms D Durocher, IA Taylor, D Sarbassova, LF Haire, SL Westcott, SP Jackson, ... Molecular cell 6 (5), 1169-1182, 2000 | 540 | 2000 |
The mechanism of autooxidation of myoglobin. RE Brantley, SJ Smerdon, AJ Wilkinson, EW Singleton, JS Olson Journal of Biological Chemistry 268 (10), 6995-7010, 1993 | 505 | 1993 |
Molecular basis of phosphorylation-induced activation of the NADPH oxidase Y Groemping, K Lapouge, SJ Smerdon, K Rittinger Cell 113 (3), 343-355, 2003 | 496 | 2003 |
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. SJ Smerdon, J Jäger, J Wang, LA Kohlstaedt, AJ Chirino, JM Friedman, ... Proceedings of the National Academy of Sciences 91 (9), 3911-3915, 1994 | 454 | 1994 |
A unified polymerase mechanism for nonhomologous DNA and RNA polymerases TA Steitz, SJ Smerdon, J Jäger, CM Joyce Science 266 (5193), 2022-2025, 1994 | 410 | 1994 |
Structure of the TPR Domain of p67phox in Complex with Rac· GTP K Lapouge, SJM Smith, PA Walker, SJ Gamblin, SJ Smerdon, K Rittinger Molecular cell 6 (4), 899-907, 2000 | 409 | 2000 |
Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP K Rittinger, PA Walker, JF Eccleston, K Nurmahomed, D Owen, E Laue, ... Nature 388 (6643), 693-697, 1997 | 364 | 1997 |
Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of … AK Gardino, SJ Smerdon, MB Yaffe Seminars in cancer biology 16 (3), 173-182, 2006 | 353 | 2006 |
The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways C Tarricone, B Xiao, N Justin, PA Walker, K Rittinger, SJ Gamblin, ... Nature 411 (6834), 215-219, 2001 | 310 | 2001 |
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint MATM van Vugt, AK Gardino, R Linding, GJ Ostheimer, HC Reinhardt, ... PLoS biology 8 (1), e1000287, 2010 | 287 | 2010 |
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer JA Clapperton, IA Manke, DM Lowery, T Ho, LF Haire, MB Yaffe, ... Nature structural & molecular biology 11 (6), 512-518, 2004 | 285 | 2004 |
Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2 J Li, BL Williams, LF Haire, M Goldberg, E Wilker, D Durocher, MB Yaffe, ... Molecular cell 9 (5), 1045-1054, 2002 | 278 | 2002 |
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer. J Wang, SJ Smerdon, J Jäger, LA Kohlstaedt, PA Rice, JM Friedman, ... Proceedings of the National Academy of Sciences 91 (15), 7242-7246, 1994 | 259 | 1994 |