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Haritha P. Reddy
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Year
The Neuropeptide Orexin-A Inhibits the GABAA Receptor by PKC and Ca2+/CaMKII-Dependent Phosphorylation of Its β1 Subunit
D Sachidanandan, HP Reddy, A Mani, GJ Hyde, AK Bera
Journal of molecular neuroscience 61, 459-467, 2017
222017
G protein-coupled potassium channels implicated in mouse and cellular models of GNB1 Encephalopathy
S Colombo, S Petri, B Shalomov, HP Reddy, G Tabak, RS Dhindsa, ...
BioRxiv, 697235, 2019
162019
Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels
HP Reddy, D Yakubovich, T Keren-Raifman, G Tabak, VA Tsemakhovich, ...
Iscience 24 (9), 2021
82021
Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor
S Colombo, HP Reddy, S Petri, DJ Williams, B Shalomov, RS Dhindsa, ...
Frontiers in Cellular Neuroscience 17, 1175895, 2023
52023
A revised mechanism of action of hyperaldosteronism‐linked mutations in cytosolic domains of GIRK4 (KCNJ5)
B Shalomov, R Handklo‐Jamal, HP Reddy, N Theodor, AK Bera, ...
The Journal of Physiology 600 (6), 1419-1437, 2022
52022
A selectivity filter mutation provides insights into gating regulation of a K+ channel
T Friesacher, HP Reddy, H Bernsteiner, J Carlo Combista, B Shalomov, ...
Communications Biology 5 (1), 345, 2022
32022
Ethosuximide: subunit-and Gβγ-dependent blocker and reporter of allosteric changes in GIRK channels
B Shalomov, T Friesacher, D Yakubovich, JC Combista, HP Reddy, ...
bioRxiv, 2024.06. 04.597296, 2024
2024
Allosteric inhibition of GIRK channels by ethosuximide
T Friesacher, B Shalomov, HP Reddy, H Bernsteiner, JC Combista, ...
Biophysical Journal 123 (3), 263a, 2024
2024
CHARACTERIZATION OF DISEASE PHENOTYPE IN MOUSE MODEL (GNB1I80T/+) WITH ENCEPHALOPATHY CAUSING MUTATION IN GΒ1 PROTEIN
H Reddy, D Yakubovitch, M Rubinstein, N Dascal
IBRO Neuroscience Reports 15, S130, 2023
2023
GIRK-SPECIFIC DRUGS RESCUE ALTERED CHANNEL ACTIVITY IN GNB1 ENCEPHALOPATHY
H Reddy, D Yakubovitch, T Raifman, M Pederson, B Shalomov, J Javitch, ...
IBRO Neuroscience Reports 15, S130, 2023
2023
Ethosuximide is an allosteric blocker of girk channels with Gβγ and is subunit dependent
B Shalomov, JC Combista, HP Reddy, S Dabbah, D Yakubovich, ...
Biophysical Journal 122 (3), 258a, 2023
2023
A selectivity filter mutation provides insights into gating regulation of a K+ channel
T Friesacher, HP Reddy, H Bernsteiner, JC Combista, B Shalomov, ...
Biophysical Journal 122 (3), 257a, 2023
2023
Cellular and Functional Defects in Aldosteronism-linked Cytosolic Domain Mutations in GIRK4 (KCNJ5)
RH Jamal, B Shalomov, HP Reddy, N Theodor, M Ashkar, AK Bera, ...
Biophysical Journal 118 (3), 117a, 2020
2020
GIRK4 Mutations R52H and E246K Impair Channel Gating but not Inward Rectification
B Shalomov, HP Reddy, AK Bera, N Dascal
Biophysical Journal 112 (3), 173a, 2017
2017
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Articles 1–14