Independent analysis of the flagellum surface and matrix proteomes provides insight into flagellum signaling in mammalian-infectious Trypanosoma brucei M Oberholzer, G Langousis, HKT Nguyen, EA Saada, MM Shimogawa, ... Molecular & Cellular Proteomics 10 (10), 2011 | 149 | 2011 |
Insect stage-specific receptor adenylate cyclases are localized to distinct subdomains of the Trypanosoma brucei flagellar membrane EA Saada, ZP Kabututu, M Lopez, MM Shimogawa, G Langousis, ... Eukaryotic Cell 13 (8), 1064-1076, 2014 | 81 | 2014 |
Insect stage-specific adenylate cyclases regulate social motility in African trypanosomes MA Lopez, EA Saada, KL Hill Eukaryotic Cell 14 (1), 104-112, 2015 | 72 | 2015 |
Engineering of monosized lipid-coated mesoporous silica nanoparticles for CRISPR delivery A Noureddine, A Maestas-Olguin, EA Saada, AE LaBauve, JO Agola, ... Acta Biomaterialia 114, 358-368, 2020 | 70 | 2020 |
Cell surface proteomics provides insight into stage-specific remodeling of the host-parasite interface in Trypanosoma brucei MM Shimogawa, EA Saada, AA Vashisht, WD Barshop, JA Wohlschlegel, ... Molecular & cellular proteomics 14 (7), 1977-1988, 2015 | 65 | 2015 |
eIF4F-like complexes formed by cap-binding homolog TbEIF4E5 with TbEIF4G1 or TbEIF4G2 are implicated in post-transcriptional regulation in Trypanosoma brucei ER Freire, AA Vashisht, AM Malvezzi, J Zuberek, G Langousis, EA Saada, ... RNA 20 (8), 1272-1286, 2014 | 63 | 2014 |
Trypanosoma brucei Translation Initiation Factor Homolog EIF4E6 Forms a Tripartite Cytosolic Complex with EIF4G5 and a Capping Enzyme Homolog ER Freire, AM Malvezzi, AA Vashisht, J Zuberek, EA Saada, G Langousis, ... Eukaryotic Cell 13 (7), 896-908, 2014 | 57 | 2014 |
Cyclic AMP regulates social behavior in African trypanosomes M Oberholzer, EA Saada, KL Hill MBio 6 (3), 10.1128/mbio. 01954-14, 2015 | 50 | 2015 |
Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei G Langousis, MM Shimogawa, EA Saada, AA Vashisht, R Spreafico, ... Proceedings of the National Academy of Sciences 113 (3), 632-637, 2016 | 40 | 2016 |
Use of anti-CRISPR protein AcrIIA4 as a capture ligand for CRISPR/Cas9 detection RK Johnston, KJ Seamon, EA Saada, JD Podlevsky, SS Branda, ... Biosensors and Bioelectronics 141, 111361, 2019 | 31 | 2019 |
Versatile high-throughput fluorescence assay for monitoring Cas9 activity KJ Seamon, YK Light, EA Saada, JS Schoeniger, B Harmon Analytical chemistry 90 (11), 6913-6921, 2018 | 27 | 2018 |
Discovery of small-molecule inhibitors of SARS-CoV-2 proteins using a computational and experimental pipeline EY Lau, OA Negrete, WFD Bennett, BJ Bennion, M Borucki, F Bourguet, ... Frontiers in Molecular Biosciences 8, 678701, 2021 | 22 | 2021 |
Timescale separation of positive and negative signaling creates history-dependent responses to IgE receptor stimulation B Harmon, LA Chylek, Y Liu, ED Mitra, A Mahajan, EA Saada, ... Scientific reports 7 (1), 15586, 2017 | 18 | 2017 |
"With a Little Help from My Friends"—Social Motility in Trypanosoma brucei EA Saada, SF DeMarco, MM Shimogawa, KL Hill PLOS Pathog 11 (12), e1005272, 2015 | 18 | 2015 |
Development of potent and effective synthetic SARS-CoV-2 neutralizing nanobodies MA Stefan, YK Light, JL Schwedler, PR McIlroy, CM Courtney, EA Saada, ... MAbs 13 (1), 1958663, 2021 | 15 | 2021 |
Identification of positive chemotaxis in the protozoan pathogen Trypanosoma brucei SF DeMarco, EA Saada, MA Lopez, KL Hill Msphere 5 (4), 10.1128/msphere. 00685-20, 2020 | 14 | 2020 |
High-throughput virtual screening of small molecule inhibitors for SARS-CoV-2 protein targets with deep fusion models GA Stevenson, D Jones, H Kim, WFD Bennett, BJ Bennion, M Borucki, ... Proceedings of the International Conference for High Performance Computing …, 2021 | 12 | 2021 |
Cyclic AMP regulates social behavior in African trypanosomes. mBio 6: e01954-14 M Oberholzer, EA Saada, KL Hill, S Hajduk, TE Wellems | 11 | 2015 |
Lipid-coated mesoporous silica nanoparticles for anti-viral applications via delivery of CRISPR-Cas9 ribonucleoproteins AE LaBauve, EA Saada, IKA Jones, R Mosesso, A Noureddine, J Techel, ... Scientific reports 13 (1), 6873, 2023 | 6 | 2023 |
Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants TA Desautels, KT Arrildt, AT Zemla, EY Lau, F Zhu, D Ricci, S Cronin, ... bioRxiv, 2022 | 2 | 2022 |