Andrew Leaver-Fay
Andrew Leaver-Fay
Research Assistant Professor, Biochemistry, UNC
Verified email at
Cited by
Cited by
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids
IW Davis, A Leaver-Fay, VB Chen, JN Block, GJ Kapral, X Wang, ...
Nucleic acids research 35 (suppl_2), W375-W383, 2007
ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules
A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ...
Methods in enzymology 487, 545-574, 2011
Predicting protein structures with a multiplayer online game
S Cooper, F Khatib, A Treuille, J Barbero, J Lee, M Beenen, A Leaver-Fay, ...
Nature 466 (7307), 756-760, 2010
The Rosetta all-atom energy function for macromolecular modeling and design
RF Alford, A Leaver-Fay, JR Jeliazkov, MJ O’Meara, FP DiMaio, H Park, ...
Journal of chemical theory and computation 13 (6), 3031-3048, 2017
Role of conformational sampling in computing mutation‐induced changes in protein structure and stability
EH Kellogg, A Leaver‐Fay, D Baker
Proteins: Structure, Function, and Bioinformatics 79 (3), 830-838, 2011
RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite
SJ Fleishman, A Leaver-Fay, JE Corn, EM Strauch, SD Khare, N Koga, ...
PloS one 6 (6), e20161, 2011
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
De novo enzyme design using Rosetta3
F Richter, A Leaver-Fay, SD Khare, S Bjelic, D Baker
PloS one 6 (5), e19230, 2011
Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface
SM Lewis, X Wu, A Pustilnik, A Sereno, F Huang, HL Rick, G Guntas, ...
Nature biotechnology 32 (2), 191-198, 2014
Modeling symmetric macromolecular structures in Rosetta3
F DiMaio, A Leaver-Fay, P Bradley, D Baker, I André
PloS one 6 (6), e20450, 2011
Combined covalent-electrostatic model of hydrogen bonding improves structure prediction with Rosetta
MJ O’Meara, A Leaver-Fay, MD Tyka, A Stein, K Houlihan, F DiMaio, ...
Journal of chemical theory and computation 11 (2), 609-622, 2015
The challenge of designing scientific discovery games
S Cooper, A Treuille, J Barbero, A Leaver-Fay, K Tuite, F Khatib, ...
Proceedings of the Fifth international Conference on the Foundations of …, 2010
Scientific benchmarks for guiding macromolecular energy function improvement
A Leaver-Fay, MJ O'meara, M Tyka, R Jacak, Y Song, EH Kellogg, ...
Methods in enzymology 523, 109-143, 2013
Foldit Standalone: a video game-derived protein structure manipulation interface using Rosetta
R Kleffner, J Flatten, A Leaver-Fay, D Baker, JB Siegel, F Khatib, ...
Bioinformatics 33 (17), 2765-2767, 2017
A generic program for multistate protein design
A Leaver-Fay, R Jacak, PB Stranges, B Kuhlman
PloS one 6 (7), e20937, 2011
Computational design of a PAK1 binding protein
RK Jha, A Leaver-Fay, S Yin, Y Wu, GL Butterfoss, T Szyperski, ...
Journal of molecular biology 400 (2), 257-270, 2010
Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design
K Drew, PD Renfrew, TW Craven, GL Butterfoss, FC Chou, S Lyskov, ...
PLoS One 8 (7), e67051, 2013
Computationally designed bispecific antibodies using negative state repertoires
A Leaver-Fay, KJ Froning, S Atwell, H Aldaz, A Pustilnik, F Lu, F Huang, ...
Structure 24 (4), 641-651, 2016
Computational protein design with explicit consideration of surface hydrophobic patches
R Jacak, A Leaver‐Fay, B Kuhlman
Proteins: Structure, Function, and Bioinformatics 80 (3), 825-838, 2012
Structure‐guided forcefield optimization
Y Song, M Tyka, A Leaver‐Fay, J Thompson, D Baker
Proteins: Structure, Function, and Bioinformatics 79 (6), 1898-1909, 2011
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