ALK Mutations Confer Differential Oncogenic Activation and Sensitivity to ALK Inhibition Therapy in Neuroblastoma SC Bresler, DA Weiser, PJ Huwe, JH Park, K Krytska, H Ryles, ... Cancer Cell 26 (5), 682-694, 2014 | 422 | 2014 |
Quantum and all-atom molecular dynamics simulations of protonation and divalent ion binding to phosphatidylinositol 4, 5-bisphosphate (PIP2) DR Slochower, PJ Huwe, R Bradley, R Radhakrishnan, PA Janmey Biophysical Journal 104 (2), 79a, 2013 | 56 | 2013 |
High-throughput mutagenesis reveals functional determinants for DNA targeting by activation-induced deaminase KS Gajula, PJ Huwe, CY Mo, DJ Crawford, JT Stivers, R Radhakrishnan, ... Nucleic acids research 42 (15), 9964-9975, 2014 | 29 | 2014 |
Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods S Arora, PJ Huwe, R Sikder, M Shah, AJ Browne, R Lesh, E Nicolas, ... Cancer Biology & Therapy 18 (7), 519-533, 2017 | 24 | 2017 |
Biological function derived from predicted structures in CASP11 PJ Huwe, Q Xu, MV Shapovalov, V Modi, MD Andrake, RL Dunbrack Jr Proteins: Structure, Function, and Bioinformatics 84, 370-391, 2016 | 14 | 2016 |
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods S Jain, C Bakolitsa, SE Brenner, P Radivojac, J Moult, S Repo, ... Genome Biology 25 (1), 2024 | 3 | 2024 |
Predicting the effects of clinically observed kinase mutations using molecular modeling and machine learning algorithms EJ Jordan, PJ Huwe, Y Mosse, M Lemmon, R Radhakrishnan Biophysical Journal 108 (2), 376a, 2015 | 2 | 2015 |
Molecular dynamics simulations of ion binding and protonation of phosphatidylinositol bisphosphate (PIP2) DR Slochower, PJ Huwe, RP Bradley, R Radhakrishnan, PA Janmey ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012 | 2 | 2012 |
A collaborative approach to improving representation in viral genomic surveillance PY Kim, AY Kim, JJ Newman, E Cella, TC Bishop, PJ Huwe, ON Uchakina, ... PLOS Global Public Health 3 (7), e0001935, 2023 | 1 | 2023 |
Computational methodology for mechanistic profiling of kinase domain mutations in cancers PJ Huwe, R Radhakrishnan Proceedings of the 2012 5th International Advanced Research Workshop on In …, 2012 | 1 | 2012 |
A collaborative approach to improving representation in viral genomic surveillance. PLOS Glob Public Health 3 (7): e0001935 PY Kim, AY Kim, JJ Newman, E Cella, TC Bishop, PJ Huwe | | 2023 |
A pipeline for developing a novel, predictive tool to classify variants of uncertain significance (VUS) in Lynch Syndrome S Arora, PJ Huwe, R Sikder, M Shah, S Deshpande, MJ Hall, ... Cancer Research 76 (14_Supplement), 5286-5286, 2016 | | 2016 |
Uncovering the Functional Effects of Biomolecular Mutations Through Computer Simulations P Huwe University of Pennsylvania, 2014 | | 2014 |
Understanding mutation-driven kinase activation of ALK in neuroblastoma patients PJ Huwe, SC Bresler, JH Park, DA Weiser, YP Mosse, MA Lemmon, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013 | | 2013 |
Understanding Kinase Activation of ALK in Neuroblastoma Patients PJ Huwe, S Bresler, J Park, M Lemmon, R Radhakrishnan Biophysical Journal 104 (2), 662a, 2013 | | 2013 |
Multiscale modeling of membrane curvature induction by epsin RP Bradley, D Slochower, PJ Huwe, R Radhakrishnan ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012 | | 2012 |
Relative Stability of Isomers of a Dipseudoacid PJ Huwe, DV Liskin, EJ Valente, DH Magers The 60th Southeastern Regional Meeting, 2008 | | 2008 |
COMP 188-Relative stability of isomers of a dipseudoacid PJ Huwe, DV Liskin, EJ Valente, DH Magers ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 2008 | | 2008 |
Sunday, February 3, 2013 79a DR Slochower, PJ Huwe, R Bradley, R Radhakrishnan, PA Janmey | | |
COPYRIGHT PAGE GS Stamatakos, PJ Huwe, R Radhakrishnan, G Tzedakis, E Tzamali, ... | | |