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Jin Wang
Jin Wang
Подтвержден адрес электронной почты в домене abbvie.com
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Год
Novel activities of CYP11A1 and their potential physiological significance
AT Slominski, W Li, TK Kim, I Semak, J Wang, JK Zjawiony, RC Tuckey
The Journal of steroid biochemistry and molecular biology 151, 25-37, 2015
2762015
RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy-and 20, 23-dihydroxyvitamin D
AT Slominski, TK Kim, Y Takeda, Z Janjetovic, AA Broz, C Skobowiat, ...
The FASEB Journal 28 (7), 2775, 2014
2692014
New substituted 4H-chromenes as anticancer agents
SA Patil, J Wang, XS Li, J Chen, TS Jones, A Hosni-Ahmed, R Patil, ...
Bioorganic & medicinal chemistry letters 22 (13), 4458-4461, 2012
1352012
Discovery of novel 2-aryl-4-benzoyl-imidazole (ABI-III) analogues targeting tubulin polymerization as antiproliferative agents
J Chen, S Ahn, J Wang, Y Lu, JT Dalton, DD Miller, W Li
Journal of medicinal chemistry 55 (16), 7285-7289, 2012
1212012
In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland
AT Slominski, TK Kim, HZ Shehabi, EKY Tang, HAE Benson, I Semak, ...
Molecular and cellular endocrinology 383 (1-2), 181-192, 2014
1032014
20-hydroxyvitamin D3 inhibits proliferation of cancer cells with high efficacy while being non-toxic
J Wang, A Slominski, RC Tuckey, Z Janjetovic, A Kulkarni, J Chen, ...
Anticancer research 32 (3), 739-746, 2012
952012
Design, synthesis, and biological evaluation of stable colchicine binding site tubulin inhibitors as potential anticancer agents
Y Lu, J Chen, J Wang, CM Li, S Ahn, CM Barrett, JT Dalton, W Li, ...
Journal of medicinal chemistry 57 (17), 7355-7366, 2014
942014
20S-Hydroxyvitamin D3, Noncalcemic Product of CYP11A1 Action on Vitamin D3, Exhibits Potent Antifibrogenic Activity in Vivo
A Slominski, Z Janjetovic, RC Tuckey, MN Nguyen, KG Bhattacharya, ...
The Journal of Clinical Endocrinology & Metabolism 98 (2), E298-E303, 2013
932013
Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization
J Chen, CM Li, J Wang, S Ahn, Z Wang, Y Lu, JT Dalton, DD Miller, W Li
Bioorganic & medicinal chemistry 19 (16), 4782-4795, 2011
842011
Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength
TK Kim, J Wang, Z Janjetovic, J Chen, RC Tuckey, MN Nguyen, EKY Tang, ...
Molecular and cellular endocrinology 361 (1-2), 143-152, 2012
772012
Exosome is a mechanism of intercellular drug transfer: Application of quantitative pharmacology
J Wang, BZ Yeung, M Cui, CJ Peer, Z Lu, WD Figg, MG Wientjes, S Woo, ...
Journal of Controlled Release 268, 147-158, 2017
692017
A comprehensive review of cytochrome P450 2E1 for xenobiotic metabolism
J Chen, S Jiang, J Wang, J Renukuntla, S Sirimulla, J Chen
Drug metabolism reviews 51 (2), 178-195, 2019
672019
Discovery of 4-Aryl-2-benzoyl-imidazoles as tubulin polymerization inhibitor with potent antiproliferative properties
M Xiao, S Ahn, J Wang, J Chen, DD Miller, JT Dalton, W Li
Journal of medicinal chemistry 56 (8), 3318-3329, 2013
652013
Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity
J Chen, J Wang, TK Kim, EW Tieu, EKY Tang, Z Lin, D Kovacic, DD Miller, ...
Anticancer research 34 (5), 2153-2163, 2014
632014
Novel tubulin polymerization inhibitors overcome multidrug resistance and reduce melanoma lung metastasis
Z Wang, J Chen, J Wang, S Ahn, CM Li, Y Lu, VS Loveless, JT Dalton, ...
Pharmaceutical research 29, 3040-3052, 2012
632012
Discovery of novel second mitochondria-derived activator of caspase mimetics as selective inhibitor of apoptosis protein inhibitors
J Wang, W Li
Journal of Pharmacology and Experimental Therapeutics 349 (2), 319-329, 2014
602014
Discovery of novel resorcinol dibenzyl ethers targeting the programmed cell death-1/programmed cell death–ligand 1 interaction as potential anticancer agents
B Cheng, Y Ren, X Niu, W Wang, S Wang, Y Tu, S Liu, J Wang, D Yang, ...
Journal of medicinal chemistry 63 (15), 8338-8358, 2020
592020
Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1
EKY Tang, J Chen, Z Janjetovic, EW Tieu, AT Slominski, W Li, RC Tuckey
Drug Metabolism and Disposition 41 (5), 1112-1124, 2013
502013
Synergistic Combination of Novel Tubulin Inhibitor ABI-274 and Vemurafenib Overcomes Vemurafenib Acquired Resistance in BRAFV600E Melanoma
J Wang, J Chen, DD Miller, W Li
Molecular cancer therapeutics 13 (1), 16-26, 2014
432014
Novel compaction techniques with pellet-containing granules
X Pan, M Chen, K Han, X Peng, X Wen, B Chen, J Wang, G Li, C Wu
European journal of pharmaceutics and biopharmaceutics 75 (3), 436-442, 2010
432010
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