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Keith Hazleton
Keith Hazleton
Children’s Hospital Los Angeles/University of Southern California
Verified email at chla.usc.edu
Title
Cited by
Cited by
Year
Low diversity gut microbiota dysbiosis: drivers, functional implications and recovery
M Kriss, KZ Hazleton, NM Nusbacher, CG Martin, CA Lozupone
Current opinion in microbiology 44, 34-40, 2018
3412018
Purine and pyrimidine pathways as targets in Plasmodium falciparum
M Belen Cassera, Y Zhang, K Z Hazleton, V L Schramm
Current topics in medicinal chemistry 11 (16), 2103-2115, 2011
1682011
Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase
KZ Hazleton, MC Ho, MB Cassera, K Clinch, DR Crump, I Rosario, ...
Chemistry & biology 19 (6), 721-730, 2012
792012
Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model
MB Cassera, KZ Hazleton, EF Merino, N Obaldia III, MC Ho, AS Murkin, ...
PLoS One 6 (11), e26916, 2011
782011
Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum
MB Cassera, KZ Hazleton, PM Riegelhaupt, EF Merino, M Luo, ...
Journal of biological chemistry 283 (47), 32889-32899, 2008
682008
Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase
K Clinch, DR Crump, GB Evans, KZ Hazleton, JM Mason, VL Schramm, ...
Bioorganic & medicinal chemistry 21 (17), 5629-5646, 2013
492013
Structural characterization of the fusion of two pentapeptide repeat proteins, Np275 and Np276, from Nostoc punctiforme: Resurrection of an ancestral protein
MW Vetting, SS Hegde, KZ Hazleton, JS Blanchard
Protein science 16 (4), 755-760, 2007
372007
Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1
PM Riegelhaupt, MB Cassera, RFG Fröhlich, KZ Hazleton, JJ Hefter, ...
Molecular and biochemical parasitology 169 (1), 40-49, 2010
352010
Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases
Y Zhang, GB Evans, K Clinch, DR Crump, LD Harris, RFG Fröhlich, ...
Journal of Biological Chemistry 288 (48), 34746-34754, 2013
332013
Gastric injury secondary to button battery ingestions: a retrospective multicenter review
RT Khalaf, W Ruan, S Orkin, M Wilsey, DS Fishman, D Mallon, Z Pan, ...
Gastrointestinal endoscopy 92 (2), 276-283, 2020
202020
Multiple-ascending-dose phase 1 clinical study of the safety, tolerability, and pharmacokinetics of CRS3123, a narrow-spectrum agent with minimal disruption of normal gut …
BK Lomeli, H Galbraith, J Schettler, GA Saviolakis, W El-Amin, B Osborn, ...
Antimicrobial agents and chemotherapy 64 (1), 10.1128/aac. 01395-19, 2019
182019
Anopheles gambiae Purine Nucleoside Phosphorylase:  Catalysis, Structure, and Inhibition,
EA Taylor, A Rinaldo-Matthis, L Li, M Ghanem, KZ Hazleton, MB Cassera, ...
Biochemistry 46 (43), 12405-12415, 2007
142007
Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice
KZ Hazleton, CG Martin, DJ Orlicky, KL Arnolds, NM Nusbacher, ...
npj Biofilms and Microbiomes 8 (1), 15, 2022
62022
2019 gut microbiota for health world summit
GM Fuhler, GA Hecht, SE Foley, AC Lebron, K Hazleton
Gastroenterology 158 (1), 28-31, 2020
42020
Dietary fat and fiber impacts intestinal microbiome resilience to antibiotics and Clostridoides difficile infection in mice
KZ Hazleton, CG Martin, KL Arnolds, NM Nusbacher, N Moreno-Huizar, ...
BioRxiv, 828939, 2019
12019
A Multimodal Intervention to Reduce C. difficile Infections and Stool Testing
JM Cotter, CL Stokes, S Tong, M Birkholz, J Child, C Cost, R Coughlin, ...
Pediatrics, e2023061981, 2024
2024
EMR-based clinical decision support to address rising Clostridioides difficile rates in a pediatric hematology/oncology/BMT unit.
C Stokes, J Cotter, CR Cost, KMCOT Dorris, V Lugo, J Child, R Coughlin, ...
Journal of Clinical Oncology 40 (28_suppl), 383-383, 2022
2022
A NOVEL MULTI-OMICS ANALYSIS (VOLARE) REVEALS LIVER-DISEASE SPECIFIC ASSOCIATIONS BETWEEN GUT MICROBIOME, PORTAL METABOLOME, AND HEPATIC GENE EXPRESSION IN HUMANS
MS Kriss, J Siebert, K Hazleton, J Klawitter, E Pomfret, JJ Pomposelli, ...
HEPATOLOGY 70, 1153A-1153A, 2019
2019
Purine salvage as an antimalarial target
KZ Hazleton
Yeshiva University, 2011
2011
Metabolic and molecular evidence of adenosine kinase activity in Plasmodium falciparum.
MB Cassera, EF Merino, KZ Hazleton, JM Carlton, VL Schramm
INTERNATIONAL JOURNAL FOR PARASITOLOGY 38, S69-S69, 2008
2008
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