Gq/11 and Gi/o activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor‐subtype EC Akam, RAJ Challiss, SR Nahorski British journal of pharmacology 132 (4), 950-958, 2001 | 122 | 2001 |
The impact of cryopreservation on bone marrow-derived mesenchymal stem cells: a systematic review S Bahsoun, K Coopman, EC Akam Journal of translational medicine 17, 1-29, 2019 | 105 | 2019 |
Inverse agonist properties of atypical antipsychotic drugs E Akam, PG Strange Biochemical pharmacology 67 (11), 2039-2045, 2004 | 47 | 2004 |
Pharmacological characterization of type 1α metabotropic glutamate receptor‐stimulated [35S]‐GTPγS binding EC Akam, AM Carruthers, SR Nahorski, RA John Challiss British journal of pharmacology 121 (6), 1203-1209, 1997 | 47 | 1997 |
Substituted indole-1-acetic acids as potent and selective CRTH2 antagonists—discovery of AZD1981 T Luker, R Bonnert, S Brough, AR Cook, MR Dickinson, I Dougall, ... Bioorganic & medicinal chemistry letters 21 (21), 6288-6292, 2011 | 43 | 2011 |
Quantitative assessment of the impact of cryopreservation on human bone marrow-derived mesenchymal stem cells: up to 24 h post-thaw and beyond S Bahsoun, K Coopman, EC Akam Stem cell research & therapy 11, 1-15, 2020 | 35 | 2020 |
The role of TLR4, TNF‐α and IL‐1β in type 2 diabetes mellitus development within a North Indian population NE Doody, MM Dowejko, EC Akam, NJ Cox, JS Bhatti, P Singh, ... Annals of human genetics 81 (4), 141-146, 2017 | 34 | 2017 |
The role of dissolved oxygen levels on human mesenchymal stem cell culture success, regulatory compliance, and therapeutic potential S Bahsoun, K Coopman, NR Forsyth, EC Akam Stem Cells and Development 27 (19), 1303-1321, 2018 | 33 | 2018 |
Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma JA Schmidt, FM Bell, E Akam, C Marshall, IA Dainty, A Heinemann, ... British journal of pharmacology 168 (7), 1626-1638, 2013 | 33 | 2013 |
The lasting effects of resistance and endurance exercise interventions on breast cancer patient mental wellbeing and physical fitness J Mok, MJ Brown, EC Akam, MA Morris Scientific reports 12 (1), 3504, 2022 | 28 | 2022 |
Characterising hyperinsulinemia-induced insulin resistance in human skeletal muscle cells MC Turner, NRW Martin, DJ Player, RA Ferguson, P Wheeler, CJ Green, ... Journal of Molecular Endocrinology 64 (3), 125-132, 2020 | 24 | 2020 |
Genetic association of pro-inflammatory cytokine gene polymorphisms with coronary artery disease (CAD) in a North Indian population S Mastana, S Prakash, EC Akam, M Kirby, MR Lindley, N Sinha, ... Gene 628, 301-307, 2017 | 21 | 2017 |
Vitamin D receptor (VDR) gene polymorphism and osteoporosis risk in White British men M Kow, E Akam, P Singh, M Singh, N Cox, JS Bhatti, SP Tuck, RM Francis, ... Annals of Human Biology 46 (5), 430-433, 2019 | 20 | 2019 |
The effect of a 12-week resistance training intervention on leukocyte telomere length M Nickels, S Mastana, D Hunter, M Denniff, V Codd, E Akam Heliyon 6 (6), 2020 | 19 | 2020 |
The effect of chronic high insulin exposure upon metabolic and myogenic markers in C2C12 skeletal muscle cells and myotubes MC Turner, DJ Player, NRW Martin, EC Akam, MP Lewis Journal of Cellular Biochemistry 119 (7), 5686-5695, 2018 | 17 | 2018 |
Switching between agonists and antagonists at CRTh2 in a series of highly potent and selective biaryl phenoxyacetic acids T Luker, R Bonnert, J Schmidt, C Sargent, SW Paine, S Thom, ... Bioorganic & medicinal chemistry letters 21 (12), 3616-3621, 2011 | 17 | 2011 |
Determining conditions for successful culture of multi-cellular 3D tumour spheroids to investigate the effect of mesenchymal stem cells on breast cancer cell invasiveness MJ Brown, S Bahsoun, MA Morris, EC Akam Bioengineering 6 (4), 101, 2019 | 12 | 2019 |
Association of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with coronary artery disease (CAD) in a North Indian population S Butler, A Young, EC Akam, N Sinha, S Agrawal, S Mastana Cogent Medicine 5 (1), 1478477, 2018 | 11 | 2018 |
Genetic risk scores for the determination of type 2 diabetes mellitus (T2DM) in North India LM Shitomi-Jones, L Akam, D Hunter, P Singh, S Mastana International Journal of Environmental Research and Public Health 20 (4), 3729, 2023 | 10 | 2023 |
Genetic analysis of novel Alu insertion polymorphisms in selected indian populations S Laybourn, EC Akam, N Cox, P Singh, SS Mastana American Journal of Human Biology 28 (6), 941-944, 2016 | 9 | 2016 |