Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling P Matos, JG Collard, P Jordan Journal of Biological Chemistry 278 (50), 50442-50448, 2003 | 171 | 2003 |
Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways V Gonçalves, P Matos, P Jordan Human molecular genetics 18 (19), 3696-3707, 2009 | 133 | 2009 |
Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi CM Farinha, P Matos, MD Amaral The FEBS journal 280 (18), 4396-4406, 2013 | 120 | 2013 |
Small GTPase Rac1: structure, localization, and expression of the human gene P Matos, J Skaug, B Marques, S Beck, F Verı́ssimo, C Gespach, ... Biochemical and Biophysical Research Communications 277 (3), 741-751, 2000 | 118 | 2000 |
Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells V Gonçalves, A Henriques, J Pereira, AN Costa, MP Moyer, LF Moita, ... RNA 20 (4), 474-482, 2014 | 106 | 2014 |
Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2 S Moniz, F Verissimo, P Matos, R Brazao, E Silva, L Kotevelets, E Chastre, ... Oncogene 26 (41), 6071-6081, 2007 | 103 | 2007 |
Increased Rac1b expression sustains colorectal tumor cell survival P Matos, P Jordan Molecular Cancer Research 6 (7), 1178-1184, 2008 | 90 | 2008 |
B-Raf< sup> V600E</sup> Cooperates With Alternative Spliced Rac1b to Sustain Colorectal Cancer Cell Survival P Matos, C Oliveira, S Velho, V Gonçalves, LT da Costa, MP Moyer, ... Gastroenterology 135 (3), 899-906, 2008 | 88 | 2008 |
Expression of Rac1b stimulates NF-κB-mediated cell survival and G1/S progression P Matos, P Jordan Experimental cell research 305 (2), 292-299, 2005 | 88 | 2005 |
The β-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression V Gonçalves, P Matos, P Jordan RNA 14 (12), 2538-2549, 2008 | 82 | 2008 |
HGF stimulation of Rac1 signaling enhances pharmacological correction of the most prevalent cystic fibrosis mutant F508del-CFTR S Moniz, M Sousa, BJ Moraes, AI Mendes, M Palma, C Barreto, JI Fragata, ... ACS chemical biology 8 (2), 432-442, 2013 | 79 | 2013 |
A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint CA Loureiro, AM Matos, Â Dias-Alves, JF Pereira, I Uliyakina, P Barros, ... Science signaling 8 (377), ra48-ra48, 2015 | 59 | 2015 |
Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity S Luz, P Kongsuphol, AI Mendes, F Romeiras, M Sousa, R Schreiber, ... Molecular and cellular biology 31 (22), 4392-4404, 2011 | 59 | 2011 |
Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells P Matos, P Jordan Journal of Biological Chemistry 281 (19), 13724-13732, 2006 | 59 | 2006 |
Microcystin-LR activates the ERK1/2 kinases and stimulates the proliferation of the monkey kidney-derived cell line Vero-E6 E Dias, P Matos, P Pereira, MCC Batoréu, MJ Silva, P Jordan Toxicology in Vitro 24 (6), 1689-1695, 2010 | 54 | 2010 |
WNK2 modulates MEK1 activity through the Rho GTPase pathway S Moniz, P Matos, P Jordan Cellular signalling 20 (10), 1762-1768, 2008 | 53 | 2008 |
Laminin-5-integrin interaction signals through PI 3-kinase and Rac1b to promote assembly of adherens junctions in HT-29 cells NT Chartier, M Lainé, S Gout, G Pawlak, CA Marie, P Matos, MR Block, ... Journal of cell science 119 (1), 31-46, 2006 | 50 | 2006 |
Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b P Matos, L Kotelevets, V Goncalves, A Henriques, P Zerbib, MP Moyer, ... Neoplasia (New York, NY) 15 (1), 102, 2013 | 46 | 2013 |
Repairing the basic defect in cystic fibrosis–one approach is not enough CM Farinha, P Matos The FEBS journal 283 (2), 246-264, 2016 | 44 | 2016 |
Antagonistic regulation of cystic fibrosis transmembrane conductance regulator cell surface expression by protein kinases WNK4 and spleen tyrosine kinase AI Mendes, P Matos, S Moniz, S Luz, MD Amaral, CM Farinha, P Jordan Molecular and Cellular Biology 31 (19), 4076-4086, 2011 | 41 | 2011 |