| Understanding the mechanism of IL-1β secretion G Lopez-Castejon, D Brough Cytokine & growth factor reviews 22 (4), 189-195, 2011 | 1545 | 2011 |
| Nanoparticles can cause DNA damage across a cellular barrier G Bhabra, A Sood, B Fisher, L Cartwright, M Saunders, WH Evans, ... Nature nanotechnology 4 (12), 876-883, 2009 | 429 | 2009 |
| Cell volume regulation modulates NLRP3 inflammasome activation V Compan, A Baroja-Mazo, G López-Castejón, AI Gomez, CM Martínez, ... Immunity 37 (3), 487-500, 2012 | 423 | 2012 |
| Caspase-1: is IL-1 just the tip of the ICEberg? A Denes, G Lopez-Castejon, D Brough Cell death & disease 3 (7), e338-e338, 2012 | 308 | 2012 |
| Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome G Lopez-Castejon, NM Luheshi, V Compan, S High, RC Whitehead, ... Journal of Biological Chemistry 288 (4), 2721-2733, 2013 | 208 | 2013 |
| NLRP3-inflammasome activating DAMPs stimulate an inflammatory response in glia in the absence of priming which contributes to brain inflammation after injury CD Savage, G Lopez-Castejon, A Denes, D Brough Frontiers in immunology 3, 288, 2012 | 207 | 2012 |
| Canonical and non-canonical activation of NLRP3 inflammasome at the crossroad between immune tolerance and intestinal inflammation C Pellegrini, L Antonioli, G Lopez-Castejon, C Blandizzi, M Fornai Frontiers in immunology 8, 237490, 2017 | 203 | 2017 |
| Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues NM Luheshi, KJ Kovács, G Lopez-Castejon, D Brough, A Denes Journal of neuroinflammation 8, 1-5, 2011 | 185 | 2011 |
| Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen‐glucose deprivation in organotypic brain slices S Girard, D Brough, G Lopez‐Castejon, J Giles, NJ Rothwell, SM Allan Glia 61 (5), 813-824, 2013 | 168 | 2013 |
| Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming JP Green, S Yu, F Martín-Sánchez, P Pelegrin, G Lopez-Castejon, ... Proceedings of the National Academy of Sciences 115 (40), E9371-E9380, 2018 | 161 | 2018 |
| The activation of gilthead seabream professional phagocytes by different PAMPs underlines the behavioural diversity of the main innate immune cells of bony fish MP Sepulcre, G López-Castejón, J Meseguer, V Mulero Molecular immunology 44 (8), 2009-2016, 2007 | 158 | 2007 |
| Development of an acrylate derivative targeting the NLRP3 inflammasome for the treatment of inflammatory bowel disease M Cocco, C Pellegrini, H Martínez-Banaclocha, M Giorgis, E Marini, ... Journal of Medicinal Chemistry 60 (9), 3656-3671, 2017 | 146 | 2017 |
| USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation P Palazón‐Riquelme, JD Worboys, J Green, A Valera, F Martín‐Sánchez, ... EMBO reports 19 (10), e44766, 2018 | 139 | 2018 |
| P2X7 receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases G Lopez-Castejon, J Theaker, P Pelegrin, AD Clifton, M Braddock, ... The Journal of Immunology 185 (4), 2611-2619, 2010 | 138 | 2010 |
| Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro A Gritsenko, S Yu, F Martin-Sanchez, I Diaz-del-Olmo, EM Nichols, ... Frontiers in immunology 11, 565924, 2020 | 137 | 2020 |
| Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness A Sood, S Salih, D Roh, L Lacharme-Lora, M Parry, B Hardiman, ... Nature nanotechnology 6 (12), 824-833, 2011 | 128 | 2011 |
| Apoptosis-associated speck-like protein containing a CARD forms specks but does not activate caspase-1 in the absence of NLRP3 during macrophage swelling V Compan, F Martín-Sánchez, A Baroja-Mazo, G López-Castejón, ... The Journal of Immunology 194 (3), 1261-1273, 2015 | 112 | 2015 |
| Turbot TNFα gene: molecular characterization and biological activity of the recombinant protein MC Ordás, MM Costa, FJ Roca, G Lopez-Castejon, V Mulero, J Meseguer, ... Molecular immunology 44 (4), 389-400, 2007 | 111 | 2007 |
| Control of the inflammasome by the ubiquitin system G Lopez‐Castejon The FEBS journal 287 (1), 11-26, 2020 | 110 | 2020 |
| Evolution of inflammasome functions in vertebrates: Inflammasome and caspase-1 trigger fish macrophage cell death but are dispensable for the processing of IL-1β D Angosto, G López-Castejón, A López-Muñoz, MP Sepulcre, M Arizcun, ... Innate immunity 18 (6), 815-824, 2012 | 108 | 2012 |
