Dissecting the phenotypes of Dravet syndrome by gene deletion M Rubinstein, S Han, C Tai, RE Westenbroek, A Hunker, T Scheuer, ... Brain 138 (8), 2219-2233, 2015 | 130 | 2015 |
Mitochondrial regulation of the hippocampal firing rate set point and seizure susceptibility B Styr, N Gonen, D Zarhin, A Ruggiero, R Atsmon, N Gazit, G Braun, ... Neuron 102 (5), 1009-1024. e8, 2019 | 116 | 2019 |
Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome M Rubinstein, RE Westenbroek, HY Frank, CJ Jones, T Scheuer, ... Neurobiology of disease 73, 106-117, 2015 | 101 | 2015 |
Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures JH Baek, M Rubinstein, T Scheuer, JS Trimmer Journal of Biological Chemistry 289 (22), 15363-15373, 2014 | 66 | 2014 |
Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GαiGDP and Gβγ M Rubinstein, S Peleg, S Berlin, D Brass, T Keren‐Raifman, ... The Journal of physiology 587 (14), 3473-3491, 2009 | 66 | 2009 |
Transcriptional activation of the insulin-like growth factor I receptor gene by the Kruppel-like factor 6 (KLF6) tumor suppressor protein: potential interactions between KLF6 … M Rubinstein, G Idelman, SR Plymate, G Narla, SL Friedman, H Werner Endocrinology 145 (8), 3769-3777, 2004 | 62 | 2004 |
Gαi and Gβγ jointly regulate the conformations of a Gβγ effector, the neuronal G protein-activated K+ channel (GIRK) S Berlin, T Keren-Raifman, R Castel, M Rubinstein, CW Dessauer, ... Journal of Biological Chemistry 285 (9), 6179-6185, 2010 | 59 | 2010 |
A novel EWS-WT1 gene fusion product in desmoplastic small round cell tumor is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene H Werner, G Idelman, M Rubinstein, P Pattee, SR Nagalla, CT Roberts Jr Cancer letters 247 (1), 84-90, 2007 | 59 | 2007 |
Gαi3 primes the G protein‐activated K+ channels for activation by coexpressed Gβγ in intact Xenopus oocytes M Rubinstein, S Peleg, S Berlin, D Brass, N Dascal The Journal of physiology 581 (1), 17-32, 2007 | 50 | 2007 |
Novel ADNP syndrome mice reveal dramatic sex-specific peripheral gene expression with brain synaptic and tau pathologies G Karmon, S Sragovich, G Hacohen-Kleiman, I Ben-Horin-Hazak, ... Biological psychiatry 92 (1), 81-95, 2022 | 43 | 2022 |
Association of rare missense variants in the second intracellular loop of NaV1. 7 sodium channels with familial autism M Rubinstein, A Patowary, IB Stanaway, E McCord, RR Nesbitt, M Archer, ... Molecular psychiatry 23 (2), 231-239, 2018 | 38 | 2018 |
Developmental alterations in firing properties of hippocampal CA1 inhibitory and excitatory neurons in a mouse model of Dravet syndrome Y Almog, S Fadila, M Brusel, A Mavashov, K Anderson, M Rubinstein Neurobiology of disease 148, 105209, 2021 | 37 | 2021 |
Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations L Mora-Jimenez, M Valencia, R Sanchez-Carpintero, J Tønnesen, ... Molecular Therapy-Nucleic Acids 25, 585-602, 2021 | 33 | 2021 |
Convulsive seizures and some behavioral comorbidities are uncoupled in the Scn1aA1783V Dravet syndrome mouse model S Fadila, S Quinn, A Turchetti Maia, D Yakubovich, M Ovadia, ... Epilepsia 61 (10), 2289-2300, 2020 | 29 | 2020 |
Recruitment of Gβγ controls the basal activity of G‐protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1 U Kahanovitch, V Tsemakhovich, S Berlin, M Rubinstein, B Styr, R Castel, ... The Journal of physiology 592 (24), 5373-5390, 2014 | 28 | 2014 |
In vivo, in vitro and in silico correlations of four de novo SCN1A missense mutations A Nissenkorn, Y Almog, I Adler, M Safrin, M Brusel, M Marom, S Bercovich, ... PLoS One 14 (2), e0211901, 2019 | 27 | 2019 |
A quantitative model of the GIRK1/2 channel reveals that its basal and evoked activities are controlled by unequal stoichiometry of Gα and Gβγ D Yakubovich, S Berlin, U Kahanovitch, M Rubinstein, I Farhy-Tselnicker, ... PLOS Computational Biology 11 (11), e1004598, 2015 | 27 | 2015 |
Viral vector–mediated expression of NaV1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome S Fadila, B Beucher, IG Dopeso-Reyes, A Mavashov, M Brusel, ... The Journal of clinical investigation 133 (12), 2023 | 13 | 2023 |
Functional investigation of a neuronal microcircuit in the CA1 area of the hippocampus reveals synaptic dysfunction in Dravet syndrome mice Y Almog, A Mavashov, M Brusel, M Rubinstein Frontiers in Molecular Neuroscience 15, 823640, 2022 | 13 | 2022 |
Transcriptional activation of the IGF-I receptor gene by the Kruppel-like factor-6 (KLF6) tumor suppressor protein: potential interactions between KLF6 and p53 M Rubinstein, G Idelman, SR Plymate, G Narla, SL Friedman, H Werner Endocrinology 145 (8), 3769-3777, 2004 | 13 | 2004 |